cDNA Cloning and Functional Analysis of Minipig Uridine Diphosphate-
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[1] P. Gervasi,et al. Xenobiotic metabolizing cytochrome P450 in pig, a promising animal model. , 2011, Current drug metabolism.
[2] T. Tracy,et al. Correlation between Bilirubin Glucuronidation and Estradiol-3-Gluronidation in the Presence of Model UDP-Glucuronosyltransferase 1A1 Substrates/Inhibitors , 2011, Drug Metabolism and Disposition.
[3] J. Sims,et al. The utility of the minipig as an animal model in regulatory toxicology. , 2010, Journal of pharmacological and toxicological methods.
[4] H. Jinno,et al. Functional characterization of human and cynomolgus monkey UDP-glucuronosyltransferase 1A1 enzymes. , 2010, Life sciences.
[5] A. Sparreboom,et al. Pharmacogenetics of irinotecan disposition and toxicity: a review. , 2010, Current clinical pharmacology.
[6] C. Guillemette,et al. UGT genomic diversity: beyond gene duplication , 2009, Drug metabolism reviews.
[7] M. Zečević,et al. Multicriteria optimization methodology in development of HPLC separation of mycophenolic acid and mycophenolic acid glucuronide in human urine and plasma. , 2009, Journal of pharmaceutical and biomedical analysis.
[8] Shuji Ohno,et al. Determination of mRNA Expression of Human UDP-Glucuronosyltransferases and Application for Localization in Various Human Tissues by Real-Time Reverse Transcriptase-Polymerase Chain Reaction , 2009, Drug Metabolism and Disposition.
[9] P. Anzenbacher,et al. Interspecies comparison of the glucuronidation processes in the man, monkey, pig, dog and rat. , 2008, Neuro endocrinology letters.
[10] H. Jinno,et al. Functional characterization of human and cynomolgus monkey UDP-glucuronosyltransferase 1A6 enzymes. , 2006, Chemico-biological interactions.
[11] S. Nagar,et al. Pharmacogenetics of Uridine Diphosphoglucuronosyltransferase (UGT) 1A Family Members and its Role in Patient Response to Irinotecan , 2006, Drug metabolism reviews.
[12] C. Guillemette,et al. Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily. , 2005, Pharmacogenetics and genomics.
[13] P. Souček,et al. MINIPIG CYTOCHROME P450 2E1: COMPARISON WITH HUMAN ENZYME , 2005, Drug Metabolism and Disposition.
[14] Tony K L Kiang,et al. UDP-glucuronosyltransferases and clinical drug-drug interactions. , 2005, Pharmacology & therapeutics.
[15] P. Souček,et al. Model systems based on experimental animals for studies on drug metabolism in man: (mini)pig cytochromes P450 3A29 and 2E1. , 2005, Basic & clinical pharmacology & toxicology.
[16] Michael H Court,et al. Isoform-selective probe substrates for in vitro studies of human UDP-glucuronosyltransferases. , 2005, Methods in enzymology.
[17] S. Zeng,et al. Direct determination of S-(-)- and R-(+)-propranolol glucuronide in rat hepatic microsomes by RP-HPLC. , 2004, Biomedical chromatography : BMC.
[18] Olivier Bernard,et al. The main role of UGT1A9 in the hepatic metabolism of mycophenolic acid and the effects of naturally occurring variants. , 2004, Drug metabolism and disposition: the biological fate of chemicals.
[19] K. Muro,et al. Quaternary ammonium-linked glucuronidation of tamoxifen by human liver microsomes and UDP-glucuronosyltransferase 1A4. , 2004, Biochemical pharmacology.
[20] T. Kamataki,et al. Cloning CYP2D21 and CYP3A22 cDNAs from liver of miniature pigs. , 2004, Drug metabolism and disposition: the biological fate of chemicals.
[21] A. Galetin,et al. Human udp-glucuronosyltransferases: isoform selectivity and kinetics of 4-methylumbelliferone and 1-naphthol glucuronidation, effects of organic solvents, and inhibition by diclofenac and probenecid. , 2004, Drug metabolism and disposition: the biological fate of chemicals.
[22] R. Iannucci,et al. Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of posaconazole (Noxafil). , 2004, Drug metabolism and disposition: the biological fate of chemicals.
[23] D. Greenblatt,et al. Evaluation of 3'-azido-3'-deoxythymidine, morphine, and codeine as probe substrates for UDP-glucuronosyltransferase 2B7 (UGT2B7) in human liver microsomes: specificity and influence of the UGT2B7*2 polymorphism. , 2003, Drug metabolism and disposition: the biological fate of chemicals.
[24] P. A. Gregory,et al. Regulation of UDP glucuronosyltransferase genes. , 2003, Current drug metabolism.
[25] M. Shimizu,et al. Glucuronidation of propofol and its analogs by human and rat liver microsomes. , 2003, Biological & pharmaceutical bulletin.
[26] C. Guillemette. Pharmacogenomics of human UDP-glucuronosyltransferase enzymes , 2003, The Pharmacogenomics Journal.
[27] David J Greenblatt,et al. Validation of serotonin (5-hydroxtryptamine) as an in vitro substrate probe for human UDP-glucuronosyltransferase (UGT) 1A6. , 2003, Drug metabolism and disposition: the biological fate of chemicals.
[28] R. Frye,et al. Sensitive liquid chromatographic method using fluorescence detection for the determination of estradiol 3- and 17-glucuronides in rat and human liver microsomal incubations: formation kinetics. , 2002, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
[29] P. Souček,et al. Minipig cytochrome P450 3A, 2A and 2C enzymes have similar properties to human analogs , 2001, BMC pharmacology.
[30] Yoshiro Saito,et al. Human liver UDP-glucuronosyltransferase isoforms involved in the glucuronidation of 7-ethyl-10-hydroxycamptothecin , 2001, Xenobiotica; the fate of foreign compounds in biological systems.
[31] J. Ritter. Roles of glucuronidation and UDP-glucuronosyltransferases in xenobiotic bioactivation reactions. , 2000, Chemico-biological interactions.
[32] S. Wrighton,et al. Tissue distribution and interindividual variation in human UDP-glucuronosyltransferase activity: relationship between UGT1A1 promoter genotype and variability in a liver bank. , 2000, Pharmacogenetics.
[33] R. Tukey,et al. Human UDP-glucuronosyltransferases: metabolism, expression, and disease. , 2000, Annual review of pharmacology and toxicology.
[34] A. Di Rienzo,et al. Phenotype‐genotype correlation of in vitro SN‐38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism , 1999, Clinical pharmacology and therapeutics.
[35] T. Iyanagi,et al. Biochemical and molecular aspects of genetic disorders of bilirubin metabolism. , 1998, Biochimica et biophysica acta.
[36] M. Ratain,et al. Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes. , 1998, The Journal of clinical investigation.
[37] D W Nebert,et al. The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence. , 1997, Pharmacogenetics.
[38] M. Andersen,et al. Interspecies Scaling in Pharmacokinetics , 1991 .
[39] M. Khan. Minipig: Advantages and Disadvantages as a Model in Toxicity Testing , 1984 .