Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes
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[1] Y. Stern-Bach,et al. Molecular Mechanism of AMPA Receptor Modulation by TARP/Stargazin , 2017, Neuron.
[2] D. Agard,et al. MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy , 2017, Nature Methods.
[3] C. Landes,et al. Stargazin Modulation of AMPA Receptors. , 2016, Cell reports.
[4] M. Kurnikova,et al. Structural Bases of Noncompetitive Inhibition of AMPA-Subtype Ionotropic Glutamate Receptors by Antiepileptic Drugs , 2016, Neuron.
[5] S. Subramaniam,et al. Structural basis of kainate subtype glutamate receptor desensitization , 2016, Nature.
[6] E. C. Twomey,et al. Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy , 2016, Science.
[7] E. Gouaux,et al. Architecture of fully occupied GluA2 AMPA receptor–TARP complex elucidated by cryo-EM , 2016, Nature.
[8] E. Lindahl,et al. Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2 , 2016, bioRxiv.
[9] P. Biggin,et al. Distinct Structural Pathways Coordinate the Activation of AMPA Receptor-Auxiliary Subunit Complexes , 2016, Neuron.
[10] K. Roche,et al. GSG1L suppresses AMPA receptor-mediated synaptic transmission and uniquely modulates AMPA receptor kinetics in hippocampal neurons , 2016, Nature Communications.
[11] L. Wollmuth,et al. A Molecular Determinant of Subtype-Specific Desensitization in Ionotropic Glutamate Receptors , 2016, The Journal of Neuroscience.
[12] A. Sobolevsky,et al. Probing Intersubunit Interfaces in AMPA-subtype Ionotropic Glutamate Receptors , 2016, Scientific Reports.
[13] M. Farrant,et al. Auxiliary Subunit GSG1L Acts to Suppress Calcium-Permeable AMPA Receptor Function , 2015, The Journal of Neuroscience.
[14] N. Grigorieff,et al. CTFFIND4: Fast and accurate defocus estimation from electron micrographs , 2015, bioRxiv.
[15] Guanghui Yang,et al. Sampling the conformational space of the catalytic subunit of human γ-secretase , 2015, bioRxiv.
[16] Kai Zhang,et al. Gctf: Real-time CTF determination and correction , 2015, bioRxiv.
[17] Bruno Rossion,et al. Figures and figure supplements , 2014 .
[18] Nikolaus Grigorieff,et al. Measuring the optimal exposure for single particle cryo-EM using a 2.6 Å reconstruction of rotavirus VP6 , 2015, eLife.
[19] Hiroshi Suzuki,et al. Structural insight into tight junction disassembly by Clostridium perfringens enterotoxin , 2015, Science.
[20] Sjors H.W. Scheres,et al. Semi-automated selection of cryo-EM particles in RELION-1.3 , 2015, Journal of structural biology.
[21] Lori A. Passmore,et al. Ultrastable gold substrates for electron cryomicroscopy , 2014, Science.
[22] S. Ramaswamy,et al. Stargazin promotes closure of the AMPA receptor ligand-binding domain , 2014, The Journal of general physiology.
[23] E. Gouaux,et al. Screening and large-scale expression of membrane proteins in mammalian cells for structural studies , 2014, Nature Protocols.
[24] A. Sobolevsky,et al. Structure of an agonist-bound ionotropic glutamate receptor , 2014, Science.
[25] E. Gouaux,et al. Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States , 2014, Cell.
[26] Prashant Rao,et al. Structural mechanism of glutamate receptor activation and desensitization , 2014, Nature.
[27] O. Nureki,et al. Crystal structure of mouse claudin-15 , 2014 .
[28] Marco Biasini,et al. SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information , 2014, Nucleic Acids Res..
[29] O. Nureki,et al. Crystal Structure of a Claudin Provides Insight into the Architecture of Tight Junctions , 2014, Science.
[30] E. Hollander,et al. The Role of Ionotropic Glutamate Receptors in Childhood Neurodevelopmental Disorders: Autism Spectrum Disorders and Fragile X Syndrome , 2014, Current neuropharmacology.
[31] R. Henderson,et al. High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy☆ , 2013, Ultramicroscopy.
[32] Hemant D. Tagare,et al. The Local Resolution of Cryo-EM Density Maps , 2013, Nature Methods.
[33] M A Rogawski,et al. AMPA receptors as a molecular target in epilepsy therapy , 2013, Acta neurologica Scandinavica. Supplementum.
[34] Sjors H.W. Scheres,et al. RELION: Implementation of a Bayesian approach to cryo-EM structure determination , 2012, Journal of structural biology.
[35] Shaoxia Chen,et al. Prevention of overfitting in cryo-EM structure determination , 2012, Nature Methods.
[36] J. Yates,et al. Differences in AMPA and kainate receptor interactomes facilitate identification of AMPA receptor auxiliary subunit GSG1L. , 2012, Cell reports.
[37] A. Plested,et al. Coupled Control of Desensitization and Gating by the Ligand Binding Domain of Glutamate Receptors , 2012, Neuron.
[38] Uwe Schulte,et al. High-Resolution Proteomics Unravel Architecture and Molecular Diversity of Native AMPA Receptor Complexes , 2012, Neuron.
[39] P. Zwart,et al. Towards automated crystallographic structure refinement with phenix.refine , 2012, Acta crystallographica. Section D, Biological crystallography.
[40] L. Nowak,et al. Mechanisms of Modal Activation of GluA3 Receptors , 2011, Molecular Pharmacology.
[41] R. Nicoll,et al. The Expanding Social Network of Ionotropic Glutamate Receptors: TARPs and Other Transmembrane Auxiliary Subunits , 2011, Neuron.
[42] Christy F. Landes,et al. Structural landscape of the isolated ligand binding domain of single AMPA receptors , 2011, Nature chemical biology.
[43] R. Dingledine,et al. Glutamate Receptor Ion Channels: Structure, Regulation, and Function , 2010, Pharmacological Reviews.
[44] V. Jayaraman,et al. Role of dimer interface in activation and desensitization in AMPA receptors , 2010, Proceedings of the National Academy of Sciences.
[45] M. Hayden,et al. Transcriptional changes in Huntington disease identified using genome-wide expression profiling and cross-platform analysis. , 2010, Human molecular genetics.
[46] P. Emsley,et al. Features and development of Coot , 2010, Acta crystallographica. Section D, Biological crystallography.
[47] E. Gouaux,et al. X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor , 2009, Nature.
[48] M. Mayer,et al. AMPA Receptor Ligand Binding Domain Mobility Revealed by Functional Cross Linking , 2009, The Journal of Neuroscience.
[49] Devin K. Schweppe,et al. A Nondesensitizing Kainate Receptor Point Mutant , 2009, Molecular Pharmacology.
[50] E. Gouaux,et al. Crystal structure and association behaviour of the GluR2 amino‐terminal domain , 2009, The EMBO journal.
[51] D. Bowie. Ionotropic glutamate receptors & CNS disorders. , 2008, CNS & neurological disorders drug targets.
[52] S. Tomita,et al. Two Families of TARP Isoforms that Have Distinct Effects on the Kinetic Properties of AMPA Receptors and Synaptic Currents , 2007, Neuron.
[53] Y. Stern-Bach,et al. Block of Kainate Receptor Desensitization Uncovers a Key Trafficking Checkpoint , 2006, Neuron.
[54] Christian Rosenmund,et al. Conformational restriction blocks glutamate receptor desensitization , 2006, Nature Structural &Molecular Biology.
[55] E. Gouaux,et al. Measurement of Conformational Changes accompanying Desensitization in an Ionotropic Glutamate Receptor , 2006, Cell.
[56] J. Howe,et al. The relationship between agonist potency and AMPA receptor kinetics. , 2006, Biophysical journal.
[57] Eric Gouaux,et al. Fluorescence-detection size-exclusion chromatography for precrystallization screening of integral membrane proteins. , 2006, Structure.
[58] David N Mastronarde,et al. Automated electron microscope tomography using robust prediction of specimen movements. , 2005, Journal of structural biology.
[59] Joshua T Dudman,et al. Mechanism of Positive Allosteric Modulators Acting on AMPA Receptors , 2005, The Journal of Neuroscience.
[60] Anchi Cheng,et al. Automated molecular microscopy: the new Leginon system. , 2005, Journal of structural biology.
[61] H. Adesnik,et al. Stargazin modulates AMPA receptor gating and trafficking by distinct domains , 2005, Nature.
[62] J. Gouaux,et al. AMPA Receptor Binding Cleft Mutations That Alter Affinity, Efficacy, and Recovery from Desensitization , 2005, The Journal of Neuroscience.
[63] P. Osten,et al. Stargazin Reduces Desensitization and Slows Deactivation of the AMPA-Type Glutamate Receptors , 2005, The Journal of Neuroscience.
[64] M. Sheng,et al. Structure and different conformational states of native AMPA receptor complexes , 2005, Nature.
[65] Conrad C. Huang,et al. UCSF Chimera—A visualization system for exploratory research and analysis , 2004, J. Comput. Chem..
[66] C. Jatzke,et al. Block of AMPA Receptor Desensitization by a Point Mutation outside the Ligand-Binding Domain , 2004, The Journal of Neuroscience.
[67] M. Mayer,et al. Structural basis for partial agonist action at ionotropic glutamate receptors , 2003, Nature Neuroscience.
[68] Eng H. Lo,et al. Neurological diseases: Mechanisms, challenges and opportunities in stroke , 2003, Nature Reviews Neuroscience.
[69] J. Howe,et al. How AMPA Receptor Desensitization Depends on Receptor Occupancy , 2003, The Journal of Neuroscience.
[70] M. Mayer,et al. Mechanism of activation and selectivity in a ligand-gated ion channel: structural and functional studies of GluR2 and quisqualate. , 2002, Biochemistry.
[71] M. Mayer,et al. Mechanism of glutamate receptor desensitization , 2002, Nature.
[72] Dane M. Chetkovich,et al. Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms , 2000, Nature.
[73] Hsiao-Wen Chen,et al. Unusual spectral energy distribution of a galaxy previously reported to be at redshift 6.68 , 2000, Nature.
[74] E. Gouaux,et al. Mechanisms for Activation and Antagonism of an AMPA-Sensitive Glutamate Receptor Crystal Structures of the GluR2 Ligand Binding Core , 2000, Neuron.
[75] M. Bennett,et al. Knockdown of AMPA Receptor GluR2 Expression Causes Delayed Neurodegeneration and Increases Damage by Sublethal Ischemia in Hippocampal CA1 and CA3 Neurons , 1999, The Journal of Neuroscience.
[76] Christian Rosenmund,et al. A Point Mutation in the Glutamate Binding Site Blocks Desensitization of AMPA Receptors , 1998, Neuron.
[77] B. Gustafsson,et al. Ionotropic glutamate receptors , 1996, Molecular Neurobiology.
[78] P. Seeburg,et al. RNA editing in brain controls a determinant of ion flow in glutamate-gated channels , 1991, Cell.
[79] B. Sakmann,et al. A family of AMPA-selective glutamate receptors. , 1990, Science.
[80] S. Heinemann,et al. Cloning by functional expression of a member of the glutamate receptor family , 1989, Nature.
[81] W. Lu,et al. GSG1L regulates the strength of AMPA receptor-mediated synaptic transmission but not AMPA receptor kinetics in hippocampal dentate granule neurons. , 2017, Journal of neurophysiology.
[82] A. Sobolevsky. Structure and gating of tetrameric glutamate receptors , 2015, The Journal of physiology.
[83] 张炜. Auxiliary proteins promote modal gating of AMPA- and kainate-type glutamate receptors , 2014 .
[84] Wen Jiang,et al. EMAN2: an extensible image processing suite for electron microscopy. , 2007, Journal of structural biology.