CA1 Nampt knockdown recapitulates hippocampal cognitive phenotypes in old mice which nicotinamide mononucleotide improves
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[1] S. Imai,et al. NAD + biosynthesis, aging, and disease , 2018, F1000Research.
[2] S. Imai,et al. Faculty of 1000 evaluation for NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus. , 2018 .
[3] J. Baur,et al. NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR. , 2017, Cell metabolism.
[4] V. Petegnief,et al. SIRT1 Overexpression in Mouse Hippocampus Induces Cognitive Enhancement Through Proteostatic and Neurotrophic Mechanisms , 2017, Molecular Neurobiology.
[5] Sung Goan Ji,et al. Differential Vulnerability of CA1 versus CA3 Pyramidal Neurons After Ischemia: Possible Relationship to Sources of Zn2+ Accumulation and Its Entry into and Prolonged Effects on Mitochondria , 2017, The Journal of Neuroscience.
[6] S. Imai,et al. Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice. , 2016, Cell metabolism.
[7] Yoshifumi Watanabe,et al. Hippocampal Sirtuin 1 Signaling Mediates Depression-like Behavior , 2016, Biological Psychiatry.
[8] E. Nestler,et al. SIRT1 Mediates Depression-Like Behaviors in the Nucleus Accumbens , 2016, The Journal of Neuroscience.
[9] L. Guarente,et al. It takes two to tango: NAD+ and sirtuins in aging/longevity control , 2016, npj Aging and Mechanisms of Disease.
[10] Y. Izumi,et al. Nampt is required for long-term depression and the function of GluN2B subunit-containing NMDA receptors , 2015, Brain Research Bulletin.
[11] W. Kiess,et al. Physiological and pathophysiological roles of NAMPT and NAD metabolism , 2015, Nature Reviews Endocrinology.
[12] J. Auwerx,et al. NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus. , 2015, Cell metabolism.
[13] Günther Deuschl,et al. Selective Neuronal Vulnerability of Human Hippocampal CA1 Neurons: Lesion Evolution, Temporal Course, and Pattern of Hippocampal Damage in Diffusion-Weighted MR Imaging , 2015, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[14] R. Pfundt,et al. Phenotypic and molecular insights into CASK-related disorders in males , 2015, Orphanet Journal of Rare Diseases.
[15] S. Imai,et al. Deficiency of Prdm13, a dorsomedial hypothalamus-enriched gene, mimics age-associated changes in sleep quality and adiposity , 2014, Aging cell.
[16] L. Guarente,et al. NAD+ and sirtuins in aging and disease. , 2014, Trends in cell biology.
[17] S. Imai,et al. Systemic regulation of mammalian ageing and longevity by brain sirtuins , 2014, Nature Communications.
[18] S. Imai,et al. Specific ablation of Nampt in adult neural stem cells recapitulates their functional defects during aging , 2014, The EMBO journal.
[19] Y. Izumi,et al. Expression of Nampt in Hippocampal and Cortical Excitatory Neurons Is Critical for Cognitive Function , 2014, The Journal of Neuroscience.
[20] M. Kreutz,et al. Binding of Y-P30 to Syndecan 2/3 Regulates the Nuclear Localization of CASK , 2014, PloS one.
[21] Jyothi Arikkath,et al. Culturing pyramidal neurons from the early postnatal mouse hippocampus and cortex , 2012, Nature Protocols.
[22] T. Yamashima,et al. Why are hippocampal CA1 neurons vulnerable but motor cortex neurons resistant to transient ischemia? , 2012, Journal of neurochemistry.
[23] Lin Du,et al. Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets , 2011, Nature Medicine.
[24] John R. Yates,et al. Sirt1 mediates neuroprotection from mutant huntingtin by activation of TORC1 and CREB transcriptional pathway , 2011, Nature Medicine.
[25] S. Imai,et al. Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. , 2011, Cell metabolism.
[26] D. Holtzman,et al. SIRT1 Promotes the Central Adaptive Response to Diet Restriction through Activation of the Dorsomedial and Lateral Nuclei of the Hypothalamus , 2010, The Journal of Neuroscience.
[27] Lois E. H. Smith,et al. SIRT1 Is Essential for Normal Cognitive Function and Synaptic Plasticity , 2010, The Journal of Neuroscience.
[28] L. Tsai,et al. A novel pathway regulates memory and plasticity via SIRT1 and miR-134 , 2010, Nature.
[29] M. Shaw,et al. CASK mutations are frequent in males and cause X-linked nystagmus and variable XLMR phenotypes , 2010, European Journal of Human Genetics.
[30] Y. Hsueh,et al. CASK phosphorylation by PKA regulates the protein–protein interactions of CASK and expression of the NMDAR2b gene , 2010, Journal of neurochemistry.
[31] X. Zhao,et al. The effects of aging on N-methyl-d-aspartate receptor subunits in the synaptic membrane and relationships to long-term spatial memory , 2009, Neuroscience.
[32] C. Aoki,et al. SAP97 and CASK mediate sorting of NMDA receptors through a previously unknown secretory pathway , 2009, Nature Neuroscience.
[33] Y. Hsueh,et al. CASK point mutation regulates protein-protein interactions and NR2b promoter activity. , 2009, Biochemical and biophysical research communications.
[34] F. Andris,et al. Nicotinamide Phosphoribosyl Transferase/Pre-B Cell Colony-Enhancing Factor/Visfatin Is Required for Lymphocyte Development and Cellular Resistance to Genotoxic Stress1 , 2008, The Journal of Immunology.
[35] Steven G Heeringa,et al. Prevalence of Cognitive Impairment without Dementia in the United States , 2008, Annals of Internal Medicine.
[36] K. Magnusson,et al. Age-related declines in a two-day reference memory task are associated with changes in NMDA receptor subunits in mice , 2007, BMC Neuroscience.
[37] Y. Hsueh. The role of the MAGUK protein CASK in neural development and synaptic function. , 2006, Current medicinal chemistry.
[38] T. Ontl,et al. Development and aging of n-methyl-d-aspartate receptor expression in the prefrontal/frontal cortex of mice , 2004, Neuroscience.
[39] S. Imai,et al. The NAD Biosynthesis Pathway Mediated by Nicotinamide Phosphoribosyltransferase Regulates Sir2 Activity in Mammalian Cells* , 2004, Journal of Biological Chemistry.
[40] Guey-Shin Wang,et al. Identification of Tbr‐1/CASK complex target genes in neurons , 2004, Journal of neurochemistry.
[41] Guey-Shin Wang,et al. Transcriptional Modification by a CASK-Interacting Nucleosome Assembly Protein , 2004, Neuron.
[42] L. Gibbons,et al. Anxiety and Alzheimer's Disease , 2001, Journal of geriatric psychiatry and neurology.
[43] K. Magnusson. Declines in mRNA Expression of Different Subunits May Account for Differential Effects of Aging on Agonist and Antagonist Binding to the NMDA Receptor , 2000, The Journal of Neuroscience.
[44] A. Mann,et al. Anxiety and Its Treatment in the Elderly , 1999, International Psychogeriatrics.
[45] David J. Anderson,et al. Subregion- and Cell Type–Restricted Gene Knockout in Mouse Brain , 1996, Cell.
[46] D S Rae,et al. One-month prevalence of mental disorders in the United States. Based on five Epidemiologic Catchment Area sites. , 1988, Archives of general psychiatry.
[47] I. Webber,et al. The Older Population of the United States. , 1959 .
[48] Y. Hsueh,et al. Calcium/calmodulin-dependent serine protein kinase (CASK), a protein implicated in mental retardation and autism-spectrum disorders, interacts with T-Brain-1 (TBR1) to control extinction of associative memory in male mice , 2017, Journal of psychiatry & neuroscience : JPN.