Attributable sources of community-acquired carriage of Escherichia coli containing β-lactam antibiotic resistance genes a population-based modelling study

Background Extended-spectrum β-lactamase-producing Escherichia coli (ESBL-EC), plasmid-mediated AmpC-producing E coli (pAmpC-EC), and other bacteria are resistant to important β-lactam antibiotics. ESBL-EC and pAmpC-EC are increasingly reported in animals, food, the environment, and community-acquired and health-care-associated human infections. These infections are usually preceded by asymptomatic carriage, for which attributions to animal, food, environmental, and human sources remain unquantified.

[1]  M. D. de Goffau,et al.  One Health Genomic Surveillance of Escherichia coli Demonstrates Distinct Lineages and Mobile Genetic Elements in Isolates from Humans versus Livestock , 2018, mBio.

[2]  M. Bonten,et al.  Molecular relatedness of ESBL/AmpC-producing Escherichia coli from humans, animals, food and the environment: a pooled analysis , 2018, The Journal of antimicrobial chemotherapy.

[3]  W. van Pelt,et al.  Attribution of human infections with Shiga toxin‐producing Escherichia coli (STEC) to livestock sources and identification of source‐specific risk factors, The Netherlands (2010–2014) , 2018, Zoonoses and public health.

[4]  D. Heederik,et al.  Extended-spectrum β-lactamase- and pAmpC-producing Enterobacteriaceae among the general population in a livestock-dense area. , 2017, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

[5]  M. Bonten,et al.  ESBL/AmpC-producing Enterobacteriaceae in households with children of preschool age: prevalence, risk factors and co-carriage , 2017, The Journal of antimicrobial chemotherapy.

[6]  Jurgen E. Chardon,et al.  Comparative Exposure Assessment of ESBL-Producing Escherichia coli through Meat Consumption , 2017, PloS one.

[7]  H. Vennema,et al.  Potential causative agents of acute gastroenteritis in households with preschool children: prevalence, risk factors, clinical relevance and household transmission , 2016, European Journal of Clinical Microbiology & Infectious Diseases.

[8]  W. van Pelt,et al.  Societal Burden and Correlates of Acute Gastroenteritis in Families with Preschool Children , 2016, Scientific Reports.

[9]  W. van Pelt,et al.  Prevalence and Risk Factors for Colonization With Extended-Spectrum Cephalosporin-Resistant Escherichia coli in Children Attending Daycare Centers: A Cohort Study in the Netherlands. , 2015, Journal of the Pediatric Infectious Diseases Society.

[10]  J. Kluytmans,et al.  Trends in Expanded-Spectrum Cephalosporin-Resistant Escherichia coli and Klebsiella pneumoniae among Dutch Clinical Isolates, from 2008 to 2012 , 2015, PloS one.

[11]  A. M. de Roda Husman,et al.  Prevalence and characterization of ESBL- and AmpC-producing Enterobacteriaceae on retail vegetables. , 2015, International journal of food microbiology.

[12]  M. Bonten,et al.  Less evidence for an important role of food-producing animals as source of antibiotic resistance in humans. , 2015, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[13]  A. M. de Roda Husman,et al.  Multidrug-Resistant and Extended Spectrum Beta-Lactamase-Producing Escherichia coli in Dutch Surface Water and Wastewater , 2015, PloS one.

[14]  L. Schouls,et al.  Molecular Characteristics of Extended-Spectrum Cephalosporin-Resistant Enterobacteriaceae from Humans in the Community , 2015, PloS one.

[15]  B. Duim,et al.  Longitudinal Study of Extended-Spectrum-β-Lactamase- and AmpC-Producing Enterobacteriaceae in Household Dogs , 2015, Antimicrobial Agents and Chemotherapy.

[16]  W. van Pelt,et al.  Extension of traditional infectious disease surveillance with a repeated population survey. , 2015, European journal of public health.

[17]  Rob J. L. Willems,et al.  Dissemination of Cephalosporin Resistance Genes between Escherichia coli Strains from Farm Animals and Humans by Specific Plasmid Lineages , 2014, PLoS genetics.

[18]  W. van Pelt,et al.  Salmonella source attribution based on microbial subtyping: does including data on food consumption matter? , 2014, International journal of food microbiology.

[19]  M. Kalin,et al.  Faecal carriage of extended-spectrum β-lactamase-producing Enterobacteriaceae is common 12 months after infection and is related to strain factors. , 2014, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

[20]  K. Bush,et al.  Epidemiological expansion, structural studies, and clinical challenges of new β-lactamases from gram-negative bacteria. , 2011, Annual review of microbiology.

[21]  M. Bonten,et al.  Dutch patients, retail chicken meat and poultry share the same ESBL genes, plasmids and strains. , 2011, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

[22]  G. Nichols,et al.  Attribution of human Listeria monocytogenes infections in England and Wales to ready-to-eat food sources placed on the market: adaptation of the Hald Salmonella source attribution model. , 2010, Foodborne pathogens and disease.

[23]  Simon E F Spencer,et al.  Source Attribution of Food‐Borne Zoonoses in New Zealand: A Modified Hald Model , 2009, Risk analysis : an official publication of the Society for Risk Analysis.

[24]  F. Baquero,et al.  Increasing prevalence of ESBL-producing Enterobacteriaceae in Europe. , 2008, Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin.

[25]  Y. V. van Duynhoven,et al.  Risk factors for Salmonella Enteritidis and Typhimurium (DT104 and non-DT104) infections in The Netherlands: predominant roles for raw eggs in Enteritidis and sandboxes in Typhimurium infections , 2005, Epidemiology and Infection.

[26]  D. Rubin,et al.  Inference from Iterative Simulation Using Multiple Sequences , 1992 .

[27]  J. Dissel,et al.  Rapport ESBL-Attributieanalyse (ESBLAT) : Op zoek naar de bronnen van antibioticaresistentie bij de mens , 2018 .

[28]  P. V. van Genderen,et al.  Import and spread of extended-spectrum β-lactamase-producing Enterobacteriaceae by international travellers (COMBAT study): a prospective, multicentre cohort study. , 2017, The Lancet. Infectious diseases.

[29]  R. Kloosterman,et al.  Quantifying within-household transmission of extended-spectrum β-lactamase-producing bacteria. , 2017, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

[30]  C. Dierikx,et al.  Extended-spectrum-b-lactamase- and AmpC-b-lactamase-producing Escherichia coli in Dutch broilers and broiler farmers , 2012 .

[31]  A. Silk extension in , 2002 .