Comparing observer models and feature selection methods for a task-based statistical assessment of digital breast tomsynthesis in reconstruction space

A task-based assessment of image quality1 for digital breast tomosynthesis (DBT) can be done in either the projected or reconstructed data space. As the choice of observer models and feature selection methods can vary depending on the type of task and data statistics, we previously investigated the performance of two channelized- Hotelling observer models in conjunction with 2D Laguerre-Gauss (LG) and two implementations of partial least squares (PLS) channels along with that of the Hotelling observer in binary detection tasks involving DBT projections.2, 3 The difference in these observers lies in how the spatial correlation in DBT angular projections is incorporated in the observer’s strategy to perform the given task. In the current work, we extend our method to the reconstructed data space of DBT. We investigate how various model observers including the aforementioned compare for performing the binary detection of a spherical signal embedded in structured breast phantoms with the use of DBT slices reconstructed via filtered back projection. We explore how well the model observers incorporate the spatial correlation between different numbers of reconstructed DBT slices while varying the number of projections. For this, relatively small and large scan angles (24° and 96°) are used for comparison. Our results indicate that 1) given a particular scan angle, the number of projections needed to achieve the best performance for each observer is similar across all observer/channel combinations, i.e., Np = 25 for scan angle 96° and Np = 13 for scan angle 24°, and 2) given these sufficient numbers of projections, the number of slices for each observer to achieve the best performance differs depending on the channel/observer types, which is more pronounced in the narrow scan angle case.

[1]  Kyle J. Myers,et al.  Partial Least Squares: A Method to Estimate Efficient Channels for the Ideal Observers , 2010, IEEE Transactions on Medical Imaging.

[2]  Harrison H Barrett,et al.  Validating the use of channels to estimate the ideal linear observer. , 2003, Journal of the Optical Society of America. A, Optics, image science, and vision.

[3]  E. Halpern,et al.  Assessing radiologist performance using combined digital mammography and breast tomosynthesis compared with digital mammography alone: results of a multicenter, multireader trial. , 2013, Radiology.

[4]  Aldo Badano,et al.  A statistical, task-based evaluation method for three-dimensional x-ray breast imaging systems using variable-background phantoms. , 2010, Medical physics.

[5]  Kyle J. Myers,et al.  Investigating the feasibility of using partial least squares as a method of extracting salient information for the evaluation of digital breast tomosynthesis , 2013, Medical Imaging.

[6]  J. Boone,et al.  Non-Gaussian statistical properties of breast images. , 2012, Medical physics.

[7]  Andrew D. A. Maidment,et al.  Development and characterization of an anthropomorphic breast software phantom based upon region-growing algorithm. , 2011, Medical physics.

[8]  Jeffrey A. Fessler,et al.  3D Forward and Back-Projection for X-Ray CT Using Separable Footprints , 2010, IEEE Transactions on Medical Imaging.

[9]  Kyle J Myers,et al.  A virtual trial framework for quantifying the detectability of masses in breast tomosynthesis projection data. , 2013, Medical physics.

[10]  H H Barrett,et al.  Human- and model-observer performance in ramp-spectrum noise: effects of regularization and object variability. , 2001, Journal of the Optical Society of America. A, Optics, image science, and vision.

[11]  L. Feldkamp,et al.  Practical cone-beam algorithm , 1984 .

[12]  Harrison H. Barrett,et al.  Foundations of Image Science , 2003, J. Electronic Imaging.

[13]  Ehsan Samei,et al.  Optimized image acquisition for breast tomosynthesis in projection and reconstruction space. , 2009, Medical physics.

[14]  Ewout Vansteenkiste,et al.  Channelized Hotelling observers for the assessment of volumetric imaging data sets. , 2011, Journal of the Optical Society of America. A, Optics, image science, and vision.