Naphthalene metabolism in relation to target tissue anatomy, physiology, cytotoxicity and tumorigenic mechanism of action.
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Harvey J Clewell | Kannan Krishnan | Kenneth T Bogen | K. Krishnan | H. Clewell | K. Bogen | A. Dahl | John B Morris | Curtis J Omiecinski | G. Yost | J. Morris | Janet M Benson | Alan R Dahl | Garold S Yost | John B. Morris | J. Benson | C. Omiecinski
[1] D. Morin,et al. Glutathione depletion and cytotoxicity by naphthalene 1,2-oxide in isolated hepatocytes. , 1989, Chemico-biological interactions.
[2] S. Leveson,et al. The formation of AFB(1)-macromolecular adducts in rats and humans at dietary levels of exposure. , 2004, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[3] D. Morin,et al. Site-Specific Metabolism of Naphthalene and 1-Nitronaphthalene in Dissected Airways of Rhesus Macaques , 2004, Journal of Pharmacology and Experimental Therapeutics.
[4] D O Nelson,et al. Covalent binding of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline to albumin and hemoglobin at environmentally relevant doses. Comparison of human subjects and F344 rats. , 1998, Drug metabolism and disposition: the biological fate of chemicals.
[5] Ernest Hodgson,et al. IN VITRO METABOLISM OF NAPHTHALENE BY HUMAN LIVER MICROSOMAL CYTOCHROME P450 ENZYMES , 2006, Drug Metabolism and Disposition.
[6] M. Pirmohamed,et al. Interindividual and interspecies variation in hepatic microsomal epoxide hydrolase activity: studies with cis-stilbene oxide, carbamazepine 10, 11-epoxide and naphthalene. , 1996, The Journal of pharmacology and experimental therapeutics.
[7] M. Andersen,et al. PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELING OF STYRENE AND STYRENE OXIDE RESPIRATORY-TRACT DOSIMETRY IN RODENTS AND HUMANS , 2002, Inhalation toxicology.
[8] S. Born,et al. Identification of the cytochromes P450 that catalyze coumarin 3,4-epoxidation and 3-hydroxylation. , 2002, Drug metabolism and disposition: the biological fate of chemicals.
[9] D. Morin,et al. Relationship of cytochrome P450 activity to Clara cell cytotoxicity. II. Comparison of stereoselectivity of naphthalene epoxidation in lung and nasal mucosa of mouse, hamster, rat and rhesus monkey. , 1992, The Journal of pharmacology and experimental therapeutics.
[10] J. Field,et al. Reactive oxygen species generated by PAH o-quinones cause change-in-function mutations in p53. , 2002, Chemical research in toxicology.
[11] D. Morin,et al. Glutathione depletion is a major determinant of inhaled naphthalene respiratory toxicity and naphthalene metabolism in mice. , 2004, Toxicological sciences : an official journal of the Society of Toxicology.
[12] A. Zuckerman,et al. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans , 1995, IARC monographs on the evaluation of carcinogenic risks to humans.
[13] R G Harvey,et al. Cytotoxicity and mutagenicity of polycyclic aromatic hydrocarbon ortho-quinones produced by dihydrodiol dehydrogenase. , 1996, Chemico-biological interactions.
[14] Joseph K. Haseman,et al. Naphthalene: A Respiratory Tract Toxicant and Carcinogen for Mice , 1992 .
[15] Ceinwen A Schreiner,et al. Genetic Toxicity of Naphthalene: A Review , 2003, Journal of toxicology and environmental health. Part B, Critical reviews.
[16] A. Pfeifer,et al. 3-methylindole-induced toxicity to human bronchial epithelial cell lines. , 2003, Toxicological sciences : an official journal of the Society of Toxicology.
[17] M L Shuler,et al. Use of In Vitro Data for Construction of a Physiologically Based Pharmacokinetic Model for Naphthalene in Rats and Mice To Probe Species Differences , 1999, Biotechnology progress.
[18] Lisa M. Sweeney,et al. A preliminary physiologically based pharmacokinetic model for naphthalene and naphthalene oxide in mice and rats , 1996, Annals of Biomedical Engineering.
[19] D. Brown,et al. Evidence for cytochrome P-450 mediated metabolism in the bronchiolar damage by naphthalene. , 1982, Chemico-biological interactions.
[20] G. Carlson,et al. Benzene metabolism in human lung cell lines BEAS‐2B and A549 and cells overexpressing CYP2F1 , 2004, Journal of biochemical and molecular toxicology.
[21] A R Buckpitt,et al. Naphthalene metabolism by human lung microsomal enzymes. , 1986, Toxicology.
[22] P. Montuschi,et al. Isoprostanes: markers and mediators of oxidative stress , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[23] Leslie T. Stayner,et al. IARC Monographs on the evaluation of carcinogenic risks to humans: Some traditional herbal medicines, some mycotoxins, naphthalene and styrene , 2002 .
[24] J. Vogel,et al. Initial uptake kinetics in human skin exposed to dilute aqueous trichloroethylene in vitro. , 1998, Journal of exposure analysis and environmental epidemiology.
[25] A. Dahl,et al. Metabolic capacity of nasal tissue interspecies comparisons of xenobiotic-metabolizing enzymes. , 1997, Mutation research.
[26] P. Hollenberg,et al. Mechanism-based inactivation of cytochrome P450 2B1 by 2-ethynylnaphthalene: identification of an active-site peptide. , 1993, Chemical research in toxicology.
[27] M C Kohn,et al. A physiologically based pharmacokinetic model for inhalation and intravenous administration of naphthalene in rats and mice. , 2001, Toxicology and applied pharmacology.
[28] C. Plopper,et al. Metabolism and cytotoxicity of naphthalene and its metabolites in isolated murine Clara cells. , 1994, Molecular pharmacology.
[29] Ajao Og,et al. Colorectal carcinoma in patients under the age of 30 years: a review of 11 cases. , 1988 .
[30] Jun Nakamura,et al. Possible genotoxic modes of action for naphthalene. , 2008, Regulatory toxicology and pharmacology : RTP.
[31] The naphthalene state of the science symposium: objectives, organization, structure, and charge. , 2008, Regulatory toxicology and pharmacology : RTP.
[32] J. Schenkman,et al. Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues. , 2003, Archives of biochemistry and biophysics.
[33] J. Morrow. Quantification of Isoprostanes as Indices of Oxidant Stress and the Risk of Atherosclerosis in Humans , 2004, Arteriosclerosis, thrombosis, and vascular biology.
[34] R. Baldwin,et al. Bioactivation of the Pulmonary Toxicants Naphthalene and 1-Nitronaphthalene by Rat CYP2F4 , 2005, Journal of Pharmacology and Experimental Therapeutics.
[35] E. Mimnaugh,et al. Clara cell damage and inhibition of pulmonary mixed-function oxidase activity by naphthalene. , 1981, Biochemical and biophysical research communications.
[36] Paul S Price,et al. Exposure, epidemiology and human cancer incidence of naphthalene. , 2008, Regulatory toxicology and pharmacology : RTP.
[37] R. Franklin,et al. Relationship of naphthalene and 2-methylnaphthalene metabolism to pulmonary bronchiolar epithelial cell necrosis. , 1989, Pharmacology & therapeutics.
[38] Xinxin Ding,et al. Human extrahepatic cytochromes P450: function in xenobiotic metabolism and tissue-selective chemical toxicity in the respiratory and gastrointestinal tracts. , 2003, Annual review of pharmacology and toxicology.
[39] C. Plopper,et al. Early events in naphthalene-induced acute Clara cell toxicity. II. Comparison of glutathione depletion and histopathology by airway location. , 2001, American journal of respiratory cell and molecular biology.
[40] G M Cohen,et al. Differences in naphthalene-induced toxicity in the mouse and rat. , 1985, Chemico-biological interactions.
[41] Y. Dragan,et al. Review article: the stages of gastrointestinal carcinogenesis – application of rodent models to human disease , 2000, Alimentary pharmacology & therapeutics.
[42] D Warner North,et al. A review of whole animal bioassays of the carcinogenic potential of naphthalene. , 2008, Regulatory toxicology and pharmacology : RTP.
[43] C. Plopper,et al. Tolerance to multiple doses of the pulmonary toxicant, naphthalene. , 1989, Toxicology and applied pharmacology.
[44] Moiz Mumtaz,et al. Toxicological profile for naphthalene, 1-methylnaphthalene, and 2-methylnaphthalene , 2005 .
[45] J. Pérez-Carreón,et al. Oxidative stress in carcinogenesis. Correlation between lipid peroxidation and induction of preneoplastic lesions in rat hepatocarcinogenesis. , 2005, Cancer letters.
[46] M Pirmohamed,et al. Characterisation of the toxic metabolite(s) of naphthalene. , 1996, Toxicology.
[47] J. Schenkman,et al. Expression patterns of mouse and human CYP orthologs (families 1-4) during development and in different adult tissues. , 2005, Archives of biochemistry and biophysics.
[48] C. Plopper,et al. Relationship of cytochrome P450 activity to Clara cell cytotoxicity. IV. Metabolism of naphthalene and naphthalene oxide in microdissected airways from mice, rats, and hamsters. , 1995, Molecular pharmacology.
[49] G. Carlson,et al. Metabolism of styrene by mouse and rat isolated lung cells. , 1999, Toxicological sciences : an official journal of the Society of Toxicology.
[50] E. Farber,et al. The sequential analysis of cancer development. , 1980, Advances in cancer research.
[51] J. E. Simmons,et al. Oncogenic response of strain A/J mice to inhaled chemicals. , 1986, Journal of toxicology and environmental health.
[52] B D Hammock,et al. Evidence of quinone metabolites of naphthalene covalently bound to sulfur nucleophiles of proteins of murine Clara cells after exposure to naphthalene. , 1997, Chemical research in toxicology.
[53] R. Herbert,et al. Toxicity and carcinogenicity study in F344 rats following 2 years of whole-body exposure to naphthalene vapors. , 2001, Inhalation toxicology.
[54] C. Plopper,et al. Elevated airway GSH resynthesis confers protection to Clara cells from naphthalene injury in mice made tolerant by repeated exposures. , 2000, The Journal of pharmacology and experimental therapeutics.
[55] Melissa A Troester,et al. Measurement of hemoglobin and albumin adducts of naphthalene-1,2-oxide, 1,2-naphthoquinone and 1,4-naphthoquinone after administration of naphthalene to F344 rats. , 2002, Chemico-biological interactions.
[56] R. Baldwin,et al. Comparison of Pulmonary/Nasal CYP2F Expression Levels in Rodents and Rhesus Macaque , 2004, Journal of Pharmacology and Experimental Therapeutics.
[57] F. Gonzalez,et al. Specific dehydrogenation of 3-methylindole and epoxidation of naphthalene by recombinant human CYP2F1 expressed in lymphoblastoid cells. , 1999, Drug metabolism and disposition: the biological fate of chemicals.
[58] Reversion of bioluminescent bacteria (Mutatox) to their luminescent state upon exposure to organic compounds, munitions, and metal salts. , 1994, Biomedical and environmental sciences : BES.
[59] M L Shuler,et al. Combining Cell Culture Analogue Reactor Designs and PBPK Models to Probe Mechanisms of Naphthalene Toxicity , 2000, Biotechnology progress.
[60] C. A. Fleschner,et al. Inhaled naphthalene causes dose dependent Clara cell cytotoxicity in mice but not in rats. , 2001, Toxicology and applied pharmacology.
[61] D. Morin,et al. Relationship of cytochrome P-450 activity to Clara cell cytotoxicity. I. Histopathologic comparison of the respiratory tract of mice, rats and hamsters after parenteral administration of naphthalene. , 1992, The Journal of pharmacology and experimental therapeutics.
[62] Mary Beth Genter,et al. Naphthalene toxicity in mice and aryl hydrocarbon receptor-mediated CYPs. , 2006, Biochemical and biophysical research communications.
[63] R. Herbert,et al. Morphology of Nasal Lesions in F344/N Rats Following Chronic Inhalation Exposure to Naphthalene Vapors , 2003, Toxicologic pathology.
[64] R. Baldwin,et al. NAPHTHALENE-INDUCED RESPIRATORY TRACT TOXICITY: METABOLIC MECHANISMS OF TOXICITY , 2002, Drug metabolism reviews.
[65] A. Burlingame,et al. Attomole Detection of in Vivo Protein Targets of Benzene in Mice , 2002, Molecular & Cellular Proteomics.
[66] R J Edwards,et al. Expression of xenobiotic-metabolizing CYPs in human pulmonary tissue. , 1999, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.
[67] E. Farber. The multistep nature of cancer development. , 1984, Cancer research.