Regional Myocardial Shape And Dimensions Of The Working Isolated Canine Left Ventricle

Regional patterns of sequential contraction of the right and left ventricles under physiological conditions, have been described (1,2) and the important detrimental role of abnormal asynchronous contraction patterns in the heart due to aberrant electrical activation or ischemic regions has also been recognized. Such data have indicated the necessity for measurements of regional myocardial function over a major portion of the ventricular wall but for practical technological reasons most geometric measurements made directly on the dynamic intact heart involve a small number of regions of the ventricle. Simplifying shape assumptions such as those commonly used in calculations of ventricular volumes (3,4) or myo-cardial wall mass (5), as well as the arbitrary selection of frames of reference in the quantitation of regional dynamics all affect the validity of these indices to an unknown extent.

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