Ajoene restored behavioral patterns and liver glutathione level in morphine treated C57BL6 mice

[1]  Jaesuk Yun,et al.  Bergenin decreases the morphine-induced physical dependence via antioxidative activity in mice , 2015, Archives of pharmacal research.

[2]  J. Novotný,et al.  Morphine as a Potential Oxidative Stress-Causing Agent , 2013, Mini-reviews in organic chemistry.

[3]  H. Farghaly,et al.  Role of oxidative stress and inducible nitric oxide synthase in morphine-induced tolerance and dependence in mice. Effect of alpha-lipoic acid , 2013, Behavioural Brain Research.

[4]  Jun-Feng Wang,et al.  Abstinence from repeated amphetamine treatment induces depressive-like behaviors and oxidative damage in rat brain , 2013, Psychopharmacology.

[5]  W. Caumo,et al.  Neonatal Morphine Administration Leads to Changes in Hippocampal BDNF Levels and Antioxidant Enzyme Activity in the Adult Life of Rats , 2013, Neurochemical Research.

[6]  P. Rodgers,et al.  Rational use of opioids for management of chronic nonterminal pain. , 2012, American family physician.

[7]  Seikwan Oh,et al.  Practical Synthesis of Hydroxychromenes and Evaluation of Their Biological Activity , 2011, Molecules.

[8]  Misaki Matsumoto,et al.  Involvement of NOX1/NADPH Oxidase in Morphine-Induced Analgesia and Tolerance , 2011, The Journal of Neuroscience.

[9]  Young Woo Kim,et al.  Ajoene, a stable garlic by-product, inhibits high fat diet-induced hepatic steatosis and oxidative injury through LKB1-dependent AMPK activation. , 2011, Antioxidants & redox signaling.

[10]  M. Gutowicz,et al.  The influence of heroin abuse on glutathione-dependent enzymes in human brain. , 2011, Drug and alcohol dependence.

[11]  W. Zou,et al.  Gene knockdown with lentiviral vector‐mediated intrathecal RNA interference of protein kinase C gamma reverses chronic morphine tolerance in rats , 2010, The journal of gene medicine.

[12]  A. Trescot.  Review of the role of opioids in cancer pain. , 2010, Journal of the National Comprehensive Cancer Network : JNCCN.

[13]  S. Matecki,et al.  N-Acetylcysteine Protects against Bupivacaine-induced Myotoxicity Caused by Oxidative and Sarcoplasmic Reticulum Stress in Human Skeletal Myotubes , 2010, Anesthesiology.

[14]  Ç. H. Karadağ,et al.  Modulatory role of the endogenous nitric oxide synthase inhibitor, asymmetric dimethylarginine (ADMA), in morphine tolerance and dependence in mice , 2010, Journal of Neural Transmission.

[15]  Da Yeon Lee,et al.  Ajoene, a stable garlic by-product, has an antioxidant effect through Nrf2-mediated glutamate-cysteine ligase induction in HepG2 cells and primary hepatocytes. , 2010, The Journal of nutrition.

[16]  K. Topouridou,et al.  Evaluation of Prooxidant–Antioxidant Balance in Chronic Heroin Users in a Single Assay: An Identification Criterion For Antioxidant Supplementation , 2010, The American journal of drug and alcohol abuse.

[17]  P. García-Nogales,et al.  Deletion of the inducible nitric oxide synthase gene reduces peripheral morphine tolerance in a mouse model of chronic inflammation , 2009, Fundamental & clinical pharmacology.

[18]  S. Cuzzocrea,et al.  Supraspinal inactivation of mitochondrial superoxide dismutase is a source of peroxynitrite in the development of morphine antinociceptive tolerance , 2009, Neuroscience.

[19]  Kyeong-Man Kim,et al.  Effects of (-)-epigallocatechin gallate on the development of morphine-induced physical dependence , 2007, Archives of pharmacal research.

[20]  S. Payabvash,et al.  Chronic morphine treatment induces oxidant and apoptotic damage in the mice liver. , 2006, Life sciences.

[21]  J. Hong,et al.  Pharmacological action ofPanax Ginseng on the behavioral toxicities induced by psychotropic agents , 2005, Archives of pharmacal research.

[22]  S. Narimatsu,et al.  Bioactivation of morphine in human liver: isolation and identification of morphinone, a toxic metabolite. , 2005, Biological & pharmaceutical bulletin.

[23]  M. Laorden,et al.  Role of PKC-alpha,gamma isoforms in regulation of c-Fos and TH expression after naloxone-induced morphine withdrawal in the hypothalamic PVN and medulla oblongata catecholaminergic cell groups. , 2005, Journal of Neurochemistry.

[24]  Jing Pan,et al.  Oxidative damage of biomolecules in mouse liver induced by morphine and protected by antioxidants. , 2004, Basic & clinical pharmacology & toxicology.

[25]  P. Singhal,et al.  Role of heme oxygenase-1 in morphine-modulated apoptosis and migration of macrophages. , 2003, The Journal of infectious diseases.

[26]  S. Yamano,et al.  [Production of morphinone as a metabolite of morphine and its physiological role]. , 1999, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

[27]  I. Schlichting,et al.  Ajoene is an inhibitor and subversive substrate of human glutathione reductase and Trypanosoma cruzi trypanothione reductase: crystallographic, kinetic, and spectroscopic studies. , 1999, Journal of medicinal chemistry.

[28]  A. Vollmar,et al.  Effect of allicin and ajoene, two compounds of garlic, on inducible nitric oxide synthase. , 1998, Atherosclerosis.

[29]  S. Yamano,et al.  In vivo and in vitro formation of morphinone from morphine in rat. , 1997, Xenobiotica; the fate of foreign compounds in biological systems.

[30]  C. Jang,et al.  Antinarcotic effects of the standardized ginseng extract G115 on morphine. , 1990, Planta medica.

[31]  P. Chapple.  Heroin Addiction , 1964, British medical journal.