Neuroinflammation trajectories precede cognitive impairment after experimental meningitis—evidence from an in vivo PET study

[1]  X. Bao,et al.  Clinical PET Imaging of Microglial Activation: Implications for Microglial Therapeutics in Alzheimer’s Disease , 2018, Front. Aging Neurosci..

[2]  Jie Xu,et al.  IL‐4 mediates the delayed neurobehavioral impairments induced by neonatal hepatitis B vaccination that involves the down‐regulation of the IL‐4 receptor in the hippocampus , 2018, Cytokine.

[3]  H. Weiner,et al.  Microglial signatures and their role in health and disease , 2018, Nature Reviews Neuroscience.

[4]  D. Hines,et al.  TSPO regulation in reactive gliotic diseases , 2018, Journal of neuroscience research.

[5]  Sangeetha Sukumari-Ramesh,et al.  TSPO: An Evolutionarily Conserved Protein with Elusive Functions , 2018, International journal of molecular sciences.

[6]  Alan A. Wilson,et al.  Association of translocator protein total distribution volume with duration of untreated major depressive disorder: a cross-sectional study. , 2018, The lancet. Psychiatry.

[7]  Ben A. Barres,et al.  Normal aging induces A1-like astrocyte reactivity , 2018, Proceedings of the National Academy of Sciences.

[8]  M. Brouwer,et al.  Epidemiology of community-acquired bacterial meningitis , 2018, Current opinion in infectious diseases.

[9]  G. Bormans,et al.  Increased Expression of Translocator Protein (TSPO) Marks Pro-inflammatory Microglia but Does Not Predict Neurodegeneration , 2018, Molecular Imaging and Biology.

[10]  J. Quevedo,et al.  The translocator protein (18kDa) and its role in neuropsychiatric disorders , 2017, Neuroscience & Biobehavioral Reviews.

[11]  B. Barres,et al.  Microglia and macrophages in brain homeostasis and disease , 2017, Nature Reviews Immunology.

[12]  J. Quevedo,et al.  Prevention of Memory Impairment and Neurotrophic Factors Increased by Lithium in Wistar Rats Submitted to Pneumococcal Meningitis Model , 2017, Mediators of inflammation.

[13]  J. Soares,et al.  Increased dopamine receptor expression and anti-depressant response following deep brain stimulation of the medial forebrain bundle. , 2017, Journal of affective disorders.

[14]  F. Turkheimer,et al.  PET imaging of putative microglial activation in individuals at ultra-high risk for psychosis, recently diagnosed and chronically ill with schizophrenia , 2017, Translational Psychiatry.

[15]  J. Quevedo,et al.  Temporal changes of oxidative stress markers in Escherichia coli K1-induced experimental meningitis in a neonatal rat model , 2017, Neuroscience Letters.

[16]  Ki Duk Park,et al.  Design, synthesis, biological evaluation and molecular modelling of 2‐(2‐aryloxyphenyl)‐1,4‐dihydroisoquinolin‐3(2H)‐ones: A novel class of TSPO ligands modulating amyloid‐&bgr;‐induced mPTP opening , 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[17]  C. Zeni,et al.  Perturbations in the apoptotic pathway and mitochondrial network dynamics in peripheral blood mononuclear cells from bipolar disorder patients , 2017, Translational Psychiatry.

[18]  Denis Guilloteau,et al.  Translocator Protein-18 kDa (TSPO) Positron Emission Tomography (PET) Imaging and Its Clinical Impact in Neurodegenerative Diseases , 2017, International journal of molecular sciences.

[19]  H. Kettenmann,et al.  Microglia in Physiology and Disease. , 2017, Annual review of physiology.

[20]  C. Cunningham,et al.  Systemic TNF-α produces acute cognitive dysfunction and exaggerated sickness behavior when superimposed upon progressive neurodegeneration , 2017, Brain, Behavior, and Immunity.

[21]  Shruti V. Kabadi,et al.  Cell cycle inhibition reduces inflammatory responses, neuronal loss, and cognitive deficits induced by hypobaria exposure following traumatic brain injury , 2016, Journal of Neuroinflammation.

[22]  C. Whitney,et al.  Community-acquired bacterial meningitis , 2016, Nature Reviews Disease Primers.

[23]  S. Cherry,et al.  Persistent neuroinflammation and cognitive impairment in a rat model of acute diisopropylfluorophosphate intoxication , 2016, Journal of Neuroinflammation.

[24]  Jennifer M. Coughlin,et al.  In vivo markers of inflammatory response in recent-onset schizophrenia: a combined study using [11C]DPA-713 PET and analysis of CSF and plasma , 2016, Translational Psychiatry.

[25]  S. Kamei.  [Cognitive Impairment in Patients with Bacterial Meningitis and Encephalitides]. , 2016, Brain and nerve = Shinkei kenkyu no shinpo.

[26]  C. Granziera,et al.  In Vivo Imaging of Human Neuroinflammation. , 2016, ACS chemical neuroscience.

[27]  Yiyun Huang,et al.  Imaging robust microglial activation after lipopolysaccharide administration in humans with PET , 2015, Proceedings of the National Academy of Sciences.

[28]  H. Batoko,et al.  Enigmatic Translocator protein (TSPO) and cellular stress regulation. , 2015, Trends in biochemical sciences.

[29]  B. Gulyás,et al.  Positron Emission Tomography studies with [11C]PBR28 in the Healthy Rodent Brain: Validating SUV as an Outcome Measure of Neuroinflammation , 2015, PloS one.

[30]  D. Haleem,et al.  Effects of clinically relevant doses of methyphenidate on spatial memory, behavioral sensitization and open field habituation: A time related study , 2015, Behavioural Brain Research.

[31]  Eduardo Rigon Zimmer,et al.  A New Device for Step-Down Inhibitory Avoidance Task—Effects of Low and High Frequency in a Novel Device for Passive Inhibitory Avoidance Task That Avoids Bioimpedance Variations , 2015, PloS one.

[32]  Bruce R. Rosen,et al.  Increased in vivo glial activation in patients with amyotrophic lateral sclerosis: Assessed with [11C]-PBR28 , 2015, NeuroImage: Clinical.

[33]  J. Cauley,et al.  Trajectories of inflammatory markers and cognitive decline over 10 years , 2014, Neurobiology of Aging.

[34]  J. Quevedo,et al.  Inhibition of indoleamine 2,3-dioxygenase prevented cognitive impairment in adult Wistar rats subjected to pneumococcal meningitis. , 2013, Translational research : the journal of laboratory and clinical medicine.

[35]  R. Prasad,et al.  Oxidative stress in children with bacterial meningitis. , 2013, Journal of tropical pediatrics.

[36]  J. Quevedo,et al.  Attenuation of cognitive impairment by the nonbacteriolytic antibiotic daptomycin in Wistar rats submitted to pneumococcal meningitis , 2013, BMC Neuroscience.

[37]  P. Kochanek,et al.  Global lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of acute brain injury , 2012, Nature Neuroscience.

[38]  Philippe Hantraye,et al.  Reactive Astrocytes Overexpress TSPO and Are Detected by TSPO Positron Emission Tomography Imaging , 2012, The Journal of Neuroscience.

[39]  J. Quevedo,et al.  Antioxidant treatment prevents cognitive impairment and oxidative damage in pneumococcal meningitis survivor rats , 2012, Metabolic Brain Disease.

[40]  J. Quevedo,et al.  Antioxidant treatment prevents cognitive impairment and oxidative damage in pneumococcal meningitis survivor rats , 2012, Metabolic Brain Disease.

[41]  Felipe Dal-Pizzol,et al.  Oxidative Stress, Cytokine/Chemokine and Disruption of Blood–Brain Barrier in Neonate Rats After Meningitis by Streptococcus agalactiae , 2011, Neurochemical Research.

[42]  Gerhard Rammes,et al.  Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders , 2010, Nature Reviews Drug Discovery.

[43]  R. Clark,et al.  Recognition memory and the medial temporal lobe: a new perspective , 2007, Nature Reviews Neuroscience.

[44]  S. Stanford.  The Open Field Test: reinventing the wheel , 2007, Journal of psychopharmacology.

[45]  B. Lopresti,et al.  The peripheral benzodiazepine receptor (Translocator protein 18kDa) in microglia: From pathology to imaging , 2006, Progress in Neurobiology.

[46]  J. V. Bannister,et al.  Assays for superoxide dismutase. , 2006, Methods of biochemical analysis.

[47]  H. Pfister,et al.  Pathophysiology of bacterial meningitis: mechanism(s) of neuronal injury. , 2002, The Journal of infectious diseases.

[48]  R. Dempsey,et al.  Traumatic Brain Injury Leads to Increased Expression of Peripheral-Type Benzodiazepine Receptors, Neuronal Death, and Activation of Astrocytes and Microglia in Rat Thalamus , 2000, Experimental Neurology.

[49]  Dean P. Jones,et al.  Mitochondrial control of apoptosis: the role of cytochrome c. , 1998, Biochimica et biophysica acta.

[50]  I Izquierdo,et al.  Involvement of hippocampal cAMP/cAMP-dependent protein kinase signaling pathways in a late memory consolidation phase of aversively motivated learning in rats. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[51]  G. Paradies,et al.  Cardiolipin-dependent decrease of cytochrome c oxidase activity in heart mitochondria from hypothyroid rats. , 1997, Biochimica et biophysica acta.

[52]  G. Kreutzberg.  Microglia: a sensor for pathological events in the CNS , 1996, Trends in Neurosciences.

[53]  J. Young,et al.  Edema and cell infiltration in the phorbol ester-treated mouse ear are temporally separate and can be differentially modulated by pharmacologic agents , 1989, Agents and Actions.

[54]  S. Tannenbaum,et al.  Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. , 1982, Analytical biochemistry.

[55]  Oliver H. Lowry,et al.  Protein measurement with the Folin phenol reagent. , 1951, The Journal of biological chemistry.

[56]  J. Quevedo,et al.  Klebsiella pneumoniae meningitis induces memory impairment and increases pro-inflammatory host response in the central nervous system of Wistar rats. , 2014, Journal of medical microbiology.

[57]  J. Neill,et al.  Sertindole improves sub-chronic PCP-induced reversal learning and episodic memory deficits in rodents: involvement of 5-HT6 and 5-HT2A receptor mechanisms , 2009, Psychopharmacology.

[58]  S. Leib,et al.  Bacterial meningitis causes two distinct forms of cellular damage in the hippocampal dentate gyrus in infant rats , 2003, Hippocampus.

[59]  H. H. Draper,et al.  Malondialdehyde determination as index of lipid peroxidation. , 1990, Methods in enzymology.

[60]  E. Stadtman,et al.  Determination of carbonyl content in oxidatively modified proteins. , 1990, Methods in enzymology.

[61]  H. Aebi,et al.  Catalase in vitro. , 1984, Methods in enzymology.