Enzymic products of the 2,3-oxidosqualene analog having an ethyl residue at 10-position. First trapping of the trimethylcyclohexanone ring by lanosterol synthase
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[1] G. Schulz,et al. Enzyme Mechanisms for Polycyclic Triterpene Formation. , 2000, Angewandte Chemie.
[2] T. Hoshino. Unnatural natural triterpenes produced by altering isoleucine into alanine at position 261 in hopene synthase and the importance of having the appropriate bulk size at this position for directing the stereochemical destiny during the polycyclization cascade , 2000 .
[3] T. Hoshino,et al. Further evidence that the polycyclization reaction by oxidosqualene-lanosterol cyclase proceeds via a ring expansion of the 5-membered C-ring formed by Markovnikov closure. On the enzymic products of the oxidosqualene analogue having an ethyl residue at the 15-position , 1998 .
[4] E. Corey,et al. Conversion of a C20 2,3-oxidosqualene analog to tricyclic structures with a five-membered C-ring by lanosterol synthase. Further evidence for a C-ring expansion step in sterol biosynthesis , 1996 .
[5] T. Hoshino,et al. Substitution of the methyl groups with ethyl groups at C-10 and C-15 of 2,3-oxidosqualene halts the enzymatic reaction of oxidosqualene–lanosterol cyclase at the monocyclic ring stage , 1995 .
[6] I. Abe,et al. Enzymic cyclization of 2,3-dihydrosqualene and squalene 2,3-epoxide by squalene cyclases: from pentacyclic to tetracyclic triterpenes , 1994 .
[7] G. Prestwich,et al. ENZYMATIC CYCLIZATION OF SQUALENE AND OXIDOSQUALENE TO STEROLS AND TRITERPENES , 1993 .
[8] David R. Liu,et al. The Methyl Group at C(10) of 2,3-Oxidosqualene is Crucial to the Correct Folding of This Substrate in the Cyclization-Rearrangement Step of Sterol Biosynthesis , 1992 .
[9] H. Williams,et al. Synthesis of 10,15‐[13C2]‐squalene and ‐DL‐squalene oxide , 1990 .
[10] J. Medina,et al. Vinyl group rearrangement in the enzymic cyclization of squalenoids: synthesis of 30-oxysterols , 1989 .
[11] E. E. Tamelen,et al. Cyclization studies with 14,15-oxidogeranylgeranyl acetate , 1982 .
[12] R. Coates,et al. Biogenetic-type total synthesis of (±)-farnesiferol A and (±)-farnesiferol C , 1982 .
[13] A. Burlingame,et al. Enzymic cyclization of 15-norsqualene 2,3-oxide , 1968 .