Hyphae fragments from A. fumigatus sensitize lung cells to silica particles (Min-U-Sil): Increased release of IL-1β.

[1]  E. Pearlman,et al.  Neutrophil Caspase-11 Is Required for Cleavage of Caspase-1 and Secretion of IL-1β in Aspergillus fumigatus Infection , 2018, The Journal of Immunology.

[2]  M. Lag,et al.  Silica Nanoparticle‐induced Cytokine Responses in BEAS‐2B and HBEC3‐KT Cells: Significance of Particle Size and Signalling Pathways in Different Lung Cell Cultures , 2018, Basic & clinical pharmacology & toxicology.

[3]  P. Zandstra,et al.  Convenience versus Biological Significance: Are PMA-Differentiated THP-1 Cells a Reliable Substitute for Blood-Derived Macrophages When Studying in Vitro Polarization? , 2018, Front. Pharmacol..

[4]  D. Denning,et al.  Pulmonary and sinus fungal diseases in non-immunocompromised patients. , 2017, The Lancet. Infectious diseases.

[5]  R. Ernst,et al.  Bacterial lipids: powerful modifiers of the innate immune response , 2017, F1000Research.

[6]  Nancy Quaranta,et al.  Effect of outdoor air pollution on asthma exacerbations in children and adults: Systematic review and multilevel meta-analysis , 2017, PloS one.

[7]  G. Núñez,et al.  Mechanism and Regulation of NLRP3 Inflammasome Activation. , 2016, Trends in biochemical sciences.

[8]  K. Shima,et al.  Impact of micro‐environmental changes on respiratory tract infections with intracellular bacteria , 2016, FEBS letters.

[9]  R. Brook,et al.  Environmental stressors and cardio-metabolic disease: part II–mechanistic insights , 2016, European heart journal.

[10]  R. Brook,et al.  Environmental stressors and cardio-metabolic disease: part I–epidemiologic evidence supporting a role for noise and air pollution and effects of mitigation strategies , 2016, European heart journal.

[11]  B. O'Brien,et al.  The choice of phorbol 12-myristate 13-acetate differentiation protocol influences the response of THP-1 macrophages to a pro-inflammatory stimulus. , 2016, Journal of immunological methods.

[12]  A. Solhaug,et al.  The mycotoxin alternariol induces DNA damage and modify macrophage phenotype and inflammatory responses. , 2015, Toxicology letters.

[13]  K. Kavanagh,et al.  The innate immune response to Aspergillus fumigatus at the alveolar surface. , 2015, FEMS microbiology reviews.

[14]  K. Schroder,et al.  Mechanisms of unconventional secretion of IL-1 family cytokines. , 2015, Cytokine.

[15]  H. Kawasaki A mechanistic review of silica-induced inhalation toxicity , 2015, Inhalation toxicology.

[16]  M. Lag,et al.  Activation of Proinflammatory Responses in Cells of the Airway Mucosa by Particulate Matter: Oxidant- and Non-Oxidant-Mediated Triggering Mechanisms , 2015, Biomolecules.

[17]  A. Hise,et al.  Inflammasomes in aspergillosis--it takes two to tango. , 2015, Cell host & microbe.

[18]  Si Ming Man,et al.  Concerted activation of the AIM2 and NLRP3 inflammasomes orchestrates host protection against Aspergillus infection. , 2015, Cell host & microbe.

[19]  A. Maciejewska Health effects of occupational exposure to crystalline silica in the light of current research results. , 2015, Medycyna pracy.

[20]  D. Pennington,et al.  Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease. , 2014, Biochimica et biophysica acta.

[21]  J. Mes,et al.  THP-1 cell line: an in vitro cell model for immune modulation approach. , 2014, International immunopharmacology.

[22]  A. Descoteaux,et al.  Macrophage Cytokines: Involvement in Immunity and Infectious Diseases , 2014, Front. Immunol..

[23]  G. Randolph,et al.  Origin and functions of tissue macrophages. , 2014, Immunity.

[24]  Sejal Saglani,et al.  Lung microbiota promotes tolerance to allergens in neonates via PD-L1 , 2014, Nature Medicine.

[25]  C. Gunsch,et al.  Inflammatory cytokine gene expression in THP‐1 cells exposed to Stachybotrys chartarum and Aspergillus versicolor , 2013, Environmental toxicology.

[26]  M. Lag,et al.  Comparison of non-crystalline silica nanoparticles in IL-1β release from macrophages , 2012, Particle and Fibre Toxicology.

[27]  B. Chain,et al.  Adherent Human Alveolar Macrophages Exhibit a Transient Pro-Inflammatory Profile That Confounds Responses to Innate Immune Stimulation , 2012, PloS one.

[28]  Thor Edvardsen,et al.  Increased Levels of Inflammatory Cytokines and Endothelin-1 in Alveolar Macrophages from Patients with Chronic Heart Failure , 2012, PloS one.

[29]  Z. Qin,et al.  The use of THP-1 cells as a model for mimicking the function and regulation of monocytes and macrophages in the vasculature. , 2012, Atherosclerosis.

[30]  E. Pamer,et al.  Monocyte recruitment during infection and inflammation , 2011, Nature Reviews Immunology.

[31]  Kyle Bittinger,et al.  Topographical continuity of bacterial populations in the healthy human respiratory tract. , 2011, American journal of respiratory and critical care medicine.

[32]  V. Hornung,et al.  Activation of the inflammasome by amorphous silica and TiO2 nanoparticles in murine dendritic cells , 2011, Nanotoxicology.

[33]  G. López-Castejón,et al.  Understanding the mechanism of IL-1β secretion , 2011, Cytokine & growth factor reviews.

[34]  A. Iwasaki,et al.  Microbiota regulates immune defense against respiratory tract influenza A virus infection , 2011, Proceedings of the National Academy of Sciences.

[35]  J. Tschopp,et al.  Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1α and IL-1β , 2010, Proceedings of the National Academy of Sciences.

[36]  Y. Yoshioka,et al.  The effect of surface modification of amorphous silica particles on NLRP3 inflammasome mediated IL-1beta production, ROS production and endosomal rupture. , 2010, Biomaterials.

[37]  S. Akira,et al.  Pattern Recognition Receptors and Inflammation , 2010, Cell.

[38]  Marc Daigneault,et al.  The Identification of Markers of Macrophage Differentiation in PMA-Stimulated THP-1 Cells and Monocyte-Derived Macrophages , 2010, PloS one.

[39]  N. Keller,et al.  Pathogenesis of Aspergillus fumigatus in Invasive Aspergillosis , 2009, Clinical Microbiology Reviews.

[40]  L. Joosten,et al.  Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages. , 2009, Blood.

[41]  I. Bièche,et al.  Aspergillus fumigatus germ tube growth and not conidia ingestion induces expression of inflammatory mediator genes in the human lung epithelial cell line A549. , 2009, Journal of medical microbiology.

[42]  Eun-Jung Park,et al.  Oxidative stress and pro-inflammatory responses induced by silica nanoparticles in vivo and in vitro. , 2009, Toxicology letters.

[43]  L. Joosten,et al.  The role of NLRs and TLRs in the activation of the inflammasome , 2008 .

[44]  K. Rock,et al.  Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization , 2008, Nature Immunology.

[45]  Richard A. Flavell,et al.  The Nalp3 inflammasome is essential for the development of silicosis , 2008, Proceedings of the National Academy of Sciences.

[46]  J. Tschopp,et al.  Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica , 2008, Science.

[47]  M. Lag,et al.  IL-1β as a determinant in silica-induced cytokine responses in monocyte-endothelial cell co-cultures , 2008, Human & experimental toxicology.

[48]  F. Paliogianni,et al.  Expression of Immunomodulatory Genes in Human Monocytes Induced by Voriconazole in the Presence of Aspergillus fumigatus , 2006, Antimicrobial Agents and Chemotherapy.

[49]  D. Beezhold,et al.  Airborne fungal fragments and allergenicity. , 2006, Medical mycology.

[50]  Bart N Lambrecht,et al.  Alveolar macrophage in the driver's seat. , 2006, Immunity.

[51]  D. Underhill,et al.  Dectin-1 and TLRs Permit Macrophages to Distinguish between Different Aspergillus fumigatus Cellular States1 , 2006, The Journal of Immunology.

[52]  D. Denning,et al.  The link between fungi and severe asthma: a summary of the evidence , 2006, European Respiratory Journal.

[53]  S. Akira,et al.  Pathogen Recognition and Innate Immunity , 2006, Cell.

[54]  J. Stow,et al.  A Role for the Phagosome in Cytokine Secretion , 2005, Science.

[55]  R. Górny Filamentous microorganisms and their fragments in indoor air--a review. , 2004, Annals of agricultural and environmental medicine : AAEM.

[56]  J. Heesemann,et al.  Toll‐like receptor (TLR) 2 and TLR4 are essential for Aspergillus‐induced activation of murine macrophages , 2003, Cellular microbiology.

[57]  Frederick Fung,et al.  Health effects of indoor fungal bioaerosol exposure. , 2003, Applied occupational and environmental hygiene.

[58]  D. Golenbock,et al.  Toll-like Receptor (TLR) Signaling in Response toAspergillus fumigatus * , 2002, The Journal of Biological Chemistry.

[59]  C. Montagnoli,et al.  Dendritic Cells Transport Conidia and Hyphae of Aspergillus fumigatus from the Airways to the Draining Lymph Nodes and Initiate Disparate Th Responses to the Fungus1 , 2002, The Journal of Immunology.

[60]  G. Cooper,et al.  Occupational exposures and autoimmune diseases. , 2002, International immunopharmacology.

[61]  P. Godowski,et al.  Tissue Expression of Human Toll-Like Receptors and Differential Regulation of Toll-Like Receptor mRNAs in Leukocytes in Response to Microbes, Their Products, and Cytokines , 2002, The Journal of Immunology.

[62]  A. Aasen,et al.  Involvement of CD14 and Toll-Like Receptors in Activation of Human Monocytes by Aspergillus fumigatus Hyphae , 2001, Infection and Immunity.

[63]  R. Øvstebø,et al.  Isolation of monocytes from whole blood by density gradient centrifugation and counter-current elutriation followed by cryopreservation: six years' experience , 2000, Scandinavian journal of clinical and laboratory investigation.

[64]  S. Amar,et al.  Differentiation of Monocytes to Macrophages Primes Cells for Lipopolysaccharide Stimulation via Accumulation of Cytoplasmic Nuclear Factor κB , 1999, Infection and Immunity.

[65]  S. Akira,et al.  Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. , 1999, Immunity.

[66]  J. Latgé,et al.  Aspergillus fumigatus and Aspergillosis , 1999, Clinical Microbiology Reviews.

[67]  J. Auwerx,et al.  The human leukemia cell line, THP-1: A multifacetted model for the study of monocyte-macrophage differentiation , 1991, Experientia.

[68]  P. Schwarze,et al.  Characterization and pro‐inflammatory responses of spore and hyphae samples from various mold species , 2018, Indoor air.

[69]  E. Latz,et al.  New insights into mechanisms controlling the NLRP3 inflammasome and its role in lung disease. , 2014, The American journal of pathology.

[70]  Byung Uk Lee,et al.  Life Comes from the Air: A Short Review on Bioaerosol Control , 2011 .

[71]  J. Tschopp,et al.  The Inflammasomes , 2010, Cell.

[72]  H. S. Jung,et al.  Optimized THP-1 differentiation is required for the detection of responses to weak stimuli , 2007, Inflammation Research.

[73]  P. Scheurich,et al.  Tumor necrosis factor signaling , 2003, Cell Death and Differentiation.

[74]  Jingsong Zhang,et al.  Expression of toll-like receptors 2 and 4 and CD14 during differentiation of HL-60 cells induced by phorbol 12-myristate 13-acetate and 1 alpha, 25-dihydroxy-vitamin D(3). , 2002, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[75]  T. Wright,et al.  Cytokines in acute and chronic inflammation. , 1997, Frontiers in bioscience : a journal and virtual library.

[76]  D. Taramelli,et al.  Production of cytokines by alveolar and peritoneal macrophages stimulated by Aspergillus fumigatus conidia or hyphae. , 1996, Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology.