Glutathione peroxidase 3 is a novel clinical diagnostic biomarker and potential therapeutic target for neutrophils in rheumatoid arthritis

[1]  G. Schett,et al.  Hypoxia Promotes Neutrophil Survival After Acute Myocardial Infarction , 2022, Frontiers in Immunology.

[2]  Haopeng Li,et al.  An Oxidative Stress-Related Gene Pair (CCNB1/PKD1), Competitive Endogenous RNAs, and Immune-Infiltration Patterns Potentially Regulate Intervertebral Disc Degeneration Development , 2021, Frontiers in Immunology.

[3]  M. Herrmann,et al.  TNF induces glycolytic shift in fibroblast like synoviocytes via GLUT1 and HIF1A , 2021, Scientific Reports.

[4]  Yi Wang,et al.  Venn diagrams in bioinformatics , 2021, Briefings Bioinform..

[5]  H. L. Wright,et al.  Neutrophils in the Pathogenesis of Rheumatoid Arthritis and Systemic Lupus Erythematosus: Same Foe Different M.O. , 2021, Frontiers in Immunology.

[6]  H. L. Wright,et al.  Rheumatoid Arthritis Synovial Fluid Neutrophils Drive Inflammation Through Production of Chemokines, Reactive Oxygen Species, and Neutrophil Extracellular Traps , 2021, Frontiers in Immunology.

[7]  Liyan Wan,et al.  Neutrophil-derived lipocalin-2 in adult-onset Still’s disease: a novel biomarker of disease activity and liver damage , 2020, Rheumatology.

[8]  F. Fenaille,et al.  Gout and pseudo-gout-related crystals promote GLUT1-mediated glycolysis that governs NLRP3 and interleukin-1β activation on macrophages , 2020, Annals of the Rheumatic Diseases.

[9]  L. Alfredsson,et al.  Modifiable environmental exposure and risk of rheumatoid arthritis—current evidence from genetic studies , 2020, Arthritis Research & Therapy.

[10]  Wenhua Zhu,et al.  Upregulated PKM2 in Macrophages Exacerbates Experimental Arthritis via STAT1 Signaling , 2020, The Journal of Immunology.

[11]  Lu Jiang,et al.  Glutathione peroxidase 3 (GPX3) suppresses the growth of melanoma cells through reactive oxygen species (ROS)‐dependent stabilization of hypoxia‐inducible factor 1‐α and 2‐α , 2019, Journal of cellular biochemistry.

[12]  G. Schett,et al.  Aggregated NETs Sequester and Detoxify Extracellular Histones , 2019, Front. Immunol..

[13]  M. Garshasbi,et al.  Genetic implications in the pathogenesis of rheumatoid arthritis; an updated review. , 2019, Gene.

[14]  Youngchul Kim,et al.  Glutathione Peroxidase 3 as a Biomarker of Recurrence after Lung Cancer Surgery , 2019, Journal of clinical medicine.

[15]  M. Kaplan,et al.  Neutrophils in Rheumatoid Arthritis: Breaking Immune Tolerance and Fueling Disease. , 2019, Trends in molecular medicine.

[16]  G. Schulert,et al.  Neutrophils From Children With Systemic Juvenile Idiopathic Arthritis Exhibit Persistent Proinflammatory Activation Despite Long-Standing Clinically Inactive Disease , 2018, Front. Immunol..

[17]  N. Barbarroja,et al.  Neutrophils: Novel key players in Rheumatoid Arthritis. Current and future therapeutic targets. , 2018, Autoimmunity reviews.

[18]  M. Whiteman,et al.  Oxidative stress in autoimmune rheumatic diseases , 2018, Free radical biology & medicine.

[19]  R. Morita,et al.  Multi-omics monitoring of drug response in rheumatoid arthritis in pursuit of molecular remission , 2018, Nature Communications.

[20]  E. Donadi,et al.  Activation status of peripheral blood neutrophils and the complement system in adult rheumatoid arthritis patients undergoing combined therapy with infliximab and methotrexate , 2018, Rheumatology International.

[21]  A. Barton,et al.  Rheumatoid arthritis , 2018, Nature Reviews Disease Primers.

[22]  T. Cotter,et al.  ROS signalling in the biology of cancer. , 2017, Seminars in cell & developmental biology.

[23]  A. D’Alessandro,et al.  Oxidative modifications of glyceraldehyde 3-phosphate dehydrogenase regulate metabolic reprogramming of stored red blood cells. , 2016, Blood.

[24]  Roland Eils,et al.  Complex heatmaps reveal patterns and correlations in multidimensional genomic data , 2016, Bioinform..

[25]  A. Kettle,et al.  Reactive Oxygen Species and Neutrophil Function. , 2016, Annual review of biochemistry.

[26]  M. Zong,et al.  Decreased expression of alpha-enolase inhibits the proliferation of hypoxia-induced rheumatoid arthritis fibroblasts-like synoviocytes , 2015, Modern rheumatology.

[27]  Sheung Tat Fan,et al.  Clinical significance and therapeutic value of glutathione peroxidase 3 (GPx3) in hepatocellular carcinoma , 2014, Oncotarget.

[28]  Robert J. Moots,et al.  The multifactorial role of neutrophils in rheumatoid arthritis , 2014, Nature Reviews Rheumatology.

[29]  Caitlyn W. Barrett,et al.  Tumor suppressor function of the plasma glutathione peroxidase gpx3 in colitis-associated carcinoma. , 2013, Cancer research.

[30]  Yeong-Wook Song,et al.  α-Enolase Expressed on the Surfaces of Monocytes and Macrophages Induces Robust Synovial Inflammation in Rheumatoid Arthritis , 2012, The Journal of Immunology.

[31]  Guangchuang Yu,et al.  clusterProfiler: an R package for comparing biological themes among gene clusters. , 2012, Omics : a journal of integrative biology.

[32]  H. L. Wright,et al.  Changes in expression of membrane TNF, NF-κB activation and neutrophil apoptosis during active and resolved inflammation , 2010, Annals of the rheumatic diseases.

[33]  J. Loscalzo,et al.  Regulation of the extracellular antioxidant selenoprotein plasma glutathione peroxidase (GPx-3) in mammalian cells , 2009, Molecular and Cellular Biochemistry.

[34]  S. Horvath,et al.  WGCNA: an R package for weighted correlation network analysis , 2008, BMC Bioinformatics.

[35]  L. Alfredsson,et al.  A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunity , 2007, Arthritis research & therapy.

[36]  Sean R. Davis,et al.  GEOquery: a bridge between the Gene Expression Omnibus (GEO) and BioConductor , 2007, Bioinform..

[37]  P. Sarzi-Puttini,et al.  Biomarkers in Rheumatoid Arthritis. , 2017, The Israel Medical Association journal : IMAJ.

[38]  Tanya Barrett,et al.  The Gene Expression Omnibus Database , 2016, Statistical Genomics.

[39]  W. Nauseef.  Isolation of human neutrophils from venous blood. , 2014, Methods in molecular biology.

[40]  A. Böyum,et al.  Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. , 1968, Scandinavian journal of clinical and laboratory investigation. Supplementum.