Pre-exercise carbohydrate and fat ingestion: effects on metabolism and performance

A key goal of pre-exercise nutritional strategies is to maximize carbohydrate stores, thereby minimizing the ergolytic effects of carbohydrate depletion. Increased dietary carbohydrate intake in the days before competition increases muscle glycogen levels and enhances exercise performance in endurance events lasting 90 min or more. Ingestion of carbohydrate 3–4 h before exercise increases liver and muscle glycogen and enhances subsequent endurance exercise performance. The effects of carbohydrate ingestion on blood glucose and free fatty acid concentrations and carbohydrate oxidation during exercise persist for at least 6 h. Although an increase in plasma insulin following carbohydrate ingestion in the hour before exercise inhibits lipolysis and liver glucose output, and can lead to transient hypoglycaemia during subsequent exercise in susceptible individuals, there is no convincing evidence that this is always associated with impaired exercise performance. However, individual experience should inform individual practice. Interventions to increase fat availability before exercise have been shown to reduce carbohydrate utilization during exercise, but do not appear to have ergogenic benefits.

[1]  I. Mujika,et al.  Carbohydrate loading failed to improve 100-km cycling performance in a placebo-controlled trial. , 2000, Journal of applied physiology.

[2]  G. Heigenhauser,et al.  Dietary carbohydrate, muscle glycogen content, and endurance performance in well-trained women. , 2000, Journal of applied physiology.

[3]  M. Tarnopolsky,et al.  Carbohydrate loading and metabolism during exercise in men and women. , 1995, Journal of applied physiology.

[4]  W. M. Sherman,et al.  Carbohydrate feedings 1 h before exercise improves cycling performance. , 1991, The American journal of clinical nutrition.

[5]  A Jeukendrup,et al.  A new validated endurance performance test. , 1996, Medicine and science in sports and exercise.

[6]  C. Willíams,et al.  Pre-Exercise Carbohydrate Meal and Endurance Running Capacity when Carbohydrates are Ingested During Exercise , 1997, International journal of sports medicine.

[7]  D. O'Gorman,et al.  A moderate glycemic meal before endurance exercise can enhance performance. , 1998, Journal of applied physiology.

[8]  P. Fournier,et al.  Rapid carbohydrate loading after a short bout of near maximal-intensity exercise. , 2002, Medicine and science in sports and exercise.

[9]  D. Costill,et al.  Effects of diet on muscle triglyceride and endurance performance. , 1997, Journal of applied physiology.

[10]  T. Noakes,et al.  Influence of carbohydrate loading on fuel substrate turnover and oxidation during prolonged exercise. , 1992, Journal of applied physiology.

[11]  G. McConell,et al.  Influence of muscle glycogen on glycogenolysis and glucose uptake during exercise in humans. , 1995, Journal of applied physiology.

[12]  T. Noakes,et al.  Effects of 3 days of carbohydrate supplementation on muscle glycogen content and utilisation during a 1-h cycling performance , 1997, European Journal of Applied Physiology and Occupational Physiology.

[13]  Y. Sato,et al.  Effect of elevated blood FFA levels on endurance performance after a single fat meal ingestion. , 1998, Medicine and science in sports and exercise.

[14]  M. Tarnopolsky,et al.  Gender differences in carbohydrate loading are related to energy intake. , 2001, Journal of applied physiology.

[15]  A. Jeukendrup,et al.  Effects of pre-exercise ingestion of differing amounts of carbohydrate on subsequent metabolism and cycling performance , 2002, European Journal of Applied Physiology.

[16]  W. Evans,et al.  Effects of moderate and high glycemic index meals on metabolism and exercise performance. , 2001, Metabolism: clinical and experimental.

[17]  P. Fournier,et al.  Carbohydrate loading in human muscle: an improved 1 day protocol , 2002, European Journal of Applied Physiology.

[18]  Asker E. Jeukendrup,et al.  Effects of pre-exercise ingestion of carbohydrate on glycaemic and insulinaemic responses during subsequent exercise at differing intensities , 2002, European Journal of Applied Physiology.

[19]  S. Racette,et al.  Muscle glycogen accumulation after endurance exercise in trained and untrained individuals. , 1997, Journal of applied physiology.

[20]  H. Kuipers,et al.  Pre-Exercise Ingestion of Carbohydrate and Transient Hypoglycemia During Exercise , 1999, International journal of sports medicine.

[21]  E Hultman,et al.  Diet, muscle glycogen and physical performance. , 1967, Acta physiologica Scandinavica.

[22]  T. Noakes,et al.  The effect of a preexercise meal on time to fatigue during prolonged cycling exercise. , 1999, Medicine and science in sports and exercise.

[23]  C. Willíams,et al.  Influence of high and low glycemic index meals on endurance running capacity. , 1999, Medicine and science in sports and exercise.

[24]  W. Evans,et al.  Fructose and glucose ingestion and muscle glycogen use during submaximal exercise. , 1983, Journal of applied physiology: respiratory, environmental and exercise physiology.

[25]  D. Costill,et al.  Effect of fructose ingestion on muscle glycogen usage during exercise. , 1985, Medicine and science in sports and exercise.

[26]  D. Costill,et al.  Glycemic and insulinemic responses to multiple preexercise carbohydrate feedings. , 1997, International journal of sport nutrition.

[27]  W. M. Sherman,et al.  Effects of 4 h preexercise carbohydrate feedings on cycling performance. , 1989, Medicine and science in sports and exercise.

[28]  R. Mann,et al.  Effect of carbohydrate ingestion on glycogen resynthesis in human liver and skeletal muscle, measured by (13)C MRS. , 2000, American journal of physiology. Endocrinology and metabolism.

[29]  E. Coyle,et al.  Fatty acid oxidation is directly regulated by carbohydrate metabolism during exercise. , 1997, The American journal of physiology.

[30]  E. Coyle,et al.  Low-fat diet alters intramuscular substrates and reduces lipolysis and fat oxidation during exercise. , 2001, American journal of physiology. Endocrinology and metabolism.

[31]  E. Coyle,et al.  Lipolytic suppression following carbohydrate ingestion limits fat oxidation during exercise. , 1997, American journal of physiology. Endocrinology and metabolism.

[32]  C. Willíams,et al.  Carbohydrate intake and recovery from prolonged exercise. , 1993, International journal of sport nutrition.

[33]  J A Hawley,et al.  Influence of selected carbohydrate drinks on cycling performance and glycogen use. , 1987, Medicine and science in sports and exercise.

[34]  T. Noakes,et al.  Preexercise carbohydrate ingestion, glucose kinetics, and muscle glycogen use: effect of the glycemic index. , 2000, Journal of applied physiology.

[35]  J. Proietto,et al.  Preexercise glucose ingestion and glucose kinetics during exercise. , 1996, Journal of applied physiology.

[36]  R. Maughan,et al.  Increased fat availability enhances the capacity of trained individuals to perform prolonged exercise. , 1999, Medicine and science in sports and exercise.

[37]  D. Maclaren,et al.  Metabolic and performance responses during endurance exercise after high-fat and high-carbohydrate meals. , 1998, Journal of applied physiology.

[38]  D. Costill,et al.  Carbohydrate feedings and exercise performance: effect of initial muscle glycogen concentration. , 1993, Journal of applied physiology.

[39]  R. Hawkins,et al.  Carbohydrate intake and recovery of intermittent running capacity. , 1997, International journal of sport nutrition.

[40]  R. Maughan,et al.  The effects of exercise and diet manipulation on the capacity to perform prolonged exercise in the heat and in the cold in trained humans , 1999, The Journal of physiology.

[41]  E. Coyle,et al.  Exercise metabolism at different time intervals after a meal. , 1991, Journal of applied physiology.

[42]  E. Richter,et al.  Carbohydrate supercompensation and muscle glycogen utilization during exhaustive running in highly trained athletes , 2004, European Journal of Applied Physiology and Occupational Physiology.

[43]  K. J. Cole,et al.  Effect of fat emulsion infusion and fat feeding on muscle glycogen utilization during cycle exercise. , 1993, Journal of applied physiology.

[44]  F. Brouns,et al.  Effect of Carbohydrate Intake During Warming-up on the Regulation of Blood Glucose During Exercise* , 1989, International journal of sports medicine.

[45]  B G Denys,et al.  Effect of carbohydrate ingestion subsequent to carbohydrate supercompensation on endurance performance. , 1995, International journal of sport nutrition.

[46]  C. Willíams,et al.  Comparison between carbohydrate feedings before and during exercise on running performance during a 30-km treadmill time trial. , 1994, International journal of sport nutrition.

[47]  J. Bangsbo,et al.  The Effect of Carbohydrate Diet on Intermittent Exercise Performance , 1992, International journal of sports medicine.

[48]  M. Febbraio,et al.  CHO feeding before prolonged exercise: effect of glycemic index on muscle glycogenolysis and exercise performance. , 1996, Journal of applied physiology.

[49]  J. Hawley,et al.  Effect of short-term fat adaptation on high-intensity training. , 2002, Medicine and science in sports and exercise.

[50]  P. Hespel,et al.  No effect of glycogen level on glycogen metabolism during high intensity exercise. , 1995, Medicine and science in sports and exercise.

[51]  L. D. Shvartsman,et al.  Valence subband structure of 〈011〉‐oriented quantum wells , 1995 .

[52]  M. Febbraio,et al.  Pre-exercise carbohydrate ingestion: effect of the glycemic index on endurance exercise performance. , 1998, Medicine and science in sports and exercise.

[53]  C. Willíams,et al.  The influence of ingesting a carbohydrate-electrolyte beverage during 4 hours of recovery on subsequent endurance capacity. , 1995, International journal of sport nutrition.

[54]  J. Hawley,et al.  Effects of fat adaptation and carbohydrate restoration on prolonged endurance exercise. , 2001, Journal of applied physiology.

[55]  M. Febbraio,et al.  Effects of carbohydrate ingestion before and during exercise on glucose kinetics and performance. , 2000, Journal of applied physiology.

[56]  P D Gollnick,et al.  Diet, exercise, and glycogen changes in human muscle fibers. , 1972, Journal of applied physiology.

[57]  M. Febbraio,et al.  Effect of fat adaptation and carbohydrate restoration on metabolism and performance during prolonged cycling. , 2000, Journal of applied physiology.

[58]  M. Febbraio,et al.  Effect of altering substrate availability on metabolism and performance during intense exercise. , 2000, The British journal of nutrition.

[59]  T. Noakes,et al.  Carbohydrate intake during prolonged cycling minimizes effect of glycemic index of preexercise meal. , 1998, Journal of applied physiology.

[60]  M. Febbraio,et al.  Plasma glucose kinetics during prolonged exercise in trained humans when fed carbohydrate. , 2002, American journal of physiology. Endocrinology and metabolism.

[61]  D. Costill,et al.  Effect of pre-exercise carbohydrate feedings on endurance cycling performance. , 1987, Medicine and science in sports and exercise.

[62]  A. Jeukendrup,et al.  Effects of timing of pre-exercise ingestion of carbohydrate on subsequent metabolism and cycling performance , 2002, European Journal of Applied Physiology.

[63]  E. Coyle,et al.  Preexercise medium-chain triglyceride ingestion does not alter muscle glycogen use during exercise. , 2000, Journal of applied physiology.

[64]  B. Ekblom,et al.  High-intensity exercise and muscle glycogen availability in humans. , 1999, Acta physiologica Scandinavica.

[65]  T J Walters,et al.  Substrate usage during prolonged exercise following a preexercise meal. , 1985, Journal of applied physiology.

[66]  D. Costill,et al.  Effects of pre-exercise carbohydrate feedings on muscle glycogen use during exercise in well-trained runners , 2004, European Journal of Applied Physiology and Occupational Physiology.

[67]  E. Coyle,et al.  Metabolic responses to preexercise meals containing various carbohydrates and fat. , 1993, The American journal of clinical nutrition.

[68]  N. Christensen,et al.  The effect of different diets and of insulin on the hormonal response to prolonged exercise. , 1979, Acta physiologica Scandinavica.

[69]  R. Maughan,et al.  Comparison of the effects of pre-exercise feeding of glucose, glycerol and placebo on endurance and fuel homeostasis in man , 2004, European Journal of Applied Physiology and Occupational Physiology.

[70]  Y. Sato,et al.  Effect of 4h Preexercise High Carbohydrate and High Fat Meal Ingestion on Endurance Performance and Metabolism , 1996, International journal of sports medicine.

[71]  D. O'Gorman,et al.  Effects of a moderate glycemic meal on exercise duration and substrate utilization. , 2001, Medicine and science in sports and exercise.

[72]  R. Withers,et al.  Effect of muscle glycogen availability on maximal exercise performance , 1997, European Journal of Applied Physiology and Occupational Physiology.

[73]  E. Coyle,et al.  Effects of elevated plasma FFA and insulin on muscle glycogen usage during exercise. , 1977, Journal of applied physiology: respiratory, environmental and exercise physiology.

[74]  T D Noakes,et al.  The effects of carbohydrate loading on muscle glycogen content and cycling performance. , 1995, International journal of sport nutrition.

[75]  C. Willíams,et al.  The influence of high carbohydrate diets on endurance running performance , 2004, European Journal of Applied Physiology and Occupational Physiology.

[76]  P. Fournier,et al.  Muscle glycogen supercompensation: absence of a gender-related difference , 2001, European Journal of Applied Physiology.

[77]  R. Maughan,et al.  The effects of a glycogen-loading regimen on the capacity to perform anaerobic exercise , 2004, European Journal of Applied Physiology and Occupational Physiology.

[78]  R. Maughan,et al.  Diet composition and the performance of high-intensity exercise. , 1997, Journal of sports sciences.

[79]  D. Thomas,et al.  Carbohydrate Feeding before Exercise: Effect of Glycemic Index , 1991, International journal of sports medicine.

[80]  J. Seifert,et al.  Glycemic and insulinemic response to preexercise carbohydrate feedings. , 1994, International journal of sport nutrition.

[81]  J M Miller,et al.  Effect of Exercise-Diet Manipulation on Muscle Glycogen and Its Subsequent Utilization During Performance* , 1981, International journal of sports medicine.

[82]  A. Jeukendrup,et al.  Prevalence of hypoglycemia following pre-exercise carbohydrate ingestion is not accompanied By higher insulin sensitivity. , 2002, International journal of sport nutrition and exercise metabolism.

[83]  D. Costill,et al.  Effects of preexercise feedings on endurance performance. , 2003, Medicine and science in sports.

[84]  W. M. Sherman,et al.  Carbohydrate feedings before, during, or in combination improve cycling endurance performance. , 1991, Journal of applied physiology.

[85]  E. Coyle,et al.  Muscle glycogen utilization during prolonged strenuous exercise when fed carbohydrate. , 1986, Journal of applied physiology.

[86]  A. Jeukendrup,et al.  Effects of pre-exercise ingestion of trehalose, galactose and glucose on subsequent metabolism and cycling performance , 2002, European Journal of Applied Physiology.