Calcium ionophore A23187 reveals calcium related cellular stress as "I-Bodies": an old actor in a new role.

[1]  G. Anderson,et al.  Molecular basis of iron-loading disorders , 2010, Expert Reviews in Molecular Medicine.

[2]  C. Brooks,et al.  Specific mitochondrial calcium overload induces mitochondrial fission in prostate cancer cells. , 2010, International journal of oncology.

[3]  L. Martins,et al.  Mitochondrial quality control and neurological disease: an emerging connection , 2010, Expert Reviews in Molecular Medicine.

[4]  Fabienne C. Fiesel,et al.  PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1 , 2010, Nature Cell Biology.

[5]  T. Seyfried,et al.  Cancer as a metabolic disease , 2010, Nutrition & metabolism.

[6]  A. Bergner,et al.  Endoplasmic reticulum Ca2+-homeostasis is altered in small and non-small cell lung cancer cell lines , 2009, Journal of experimental & clinical cancer research : CR.

[7]  J. Argilés,et al.  Direct effects of doxorubicin on skeletal muscle contribute to fatigue , 2009, British Journal of Cancer.

[8]  G. Viani,et al.  Whole brain radiotherapy with radiosensitizer for brain metastases , 2009, Journal of experimental & clinical cancer research : CR.

[9]  B. Chernyak,et al.  Novel mechanism of elimination of malfunctioning mitochondria (mitoptosis): formation of mitoptotic bodies and extrusion of mitochondrial material from the cell. , 2008, Biochimica et biophysica acta.

[10]  S. Pieczenik,et al.  Medication-induced mitochondrial damage and disease. , 2008, Molecular nutrition & food research.

[11]  Guido Kroemer,et al.  Tumor cell metabolism: cancer's Achilles' heel. , 2008, Cancer cell.

[12]  G. Semenza,et al.  Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia* , 2008, Journal of Biological Chemistry.

[13]  M. Duchen,et al.  Mitochondria: the hub of cellular Ca2+ signaling. , 2008, Physiology.

[14]  H. Fujita,et al.  Mechanism of A23187-Induced Apoptosis in HL-60 Cells: Dependency on Mitochondrial Permeability Transition but Not on NADPH Oxidase , 2007, Bioscience, biotechnology, and biochemistry.

[15]  A. Florea,et al.  IP3 receptor antagonist, 2‐APB, attenuates cisplatin induced Ca2+‐influx in HeLa‐S3 cells and prevents activation of calpain and induction of apoptosis , 2007, British journal of pharmacology.

[16]  A. C. Santos,et al.  Cisplatin-induced nephrotoxicity is associated with oxidative stress, redox state unbalance, impairment of energetic metabolism and apoptosis in rat kidney mitochondria , 2007, Archives of Toxicology.

[17]  Hyeyong Kim,et al.  Hepatitis B Virus X Protein Induces Perinuclear Mitochondrial Clustering in Microtubule- and Dynein-Dependent Manners , 2006, Journal of Virology.

[18]  J. Putney,et al.  Store-operated calcium channels. , 2005, Physiological reviews.

[19]  C. Isidoro,et al.  Autophagy‐dependent cell survival and cell death in an autosomal dominant familial neurohypophyseal diabetes insipidus in vitro model , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[20]  R. Mathur,et al.  The glycolytic inhibitor 2-deoxy-D-glucose enhances the efficacy of etoposide in ehrlich ascites tumor bearing mice , 2005, Cancer biology & therapy.

[21]  P. Brookes,et al.  Calcium, ATP, and ROS: a mitochondrial love-hate triangle. , 2004, American journal of physiology. Cell physiology.

[22]  K. Gunter,et al.  Calcium and mitochondria , 2004, FEBS letters.

[23]  T. Tsuruo,et al.  Mitochondrial aggregation precedes cytochrome c release from mitochondria during apoptosis , 2003, Oncogene.

[24]  G. Amuthan,et al.  Mitochondrial stress-induced calcium signaling, phenotypic changes and invasive behavior in human lung carcinoma A549 cells , 2002, Oncogene.

[25]  J. Custódio,et al.  Thiol protecting agents and antioxidants inhibit the mitochondrial permeability transition promoted by etoposide: implications in the prevention of etoposide-induced apoptosis. , 2002, Chemico-biological interactions.

[26]  J. Skepper,et al.  Paclitaxel Affects Cytosolic Calcium Signals by Opening the Mitochondrial Permeability Transition Pore* , 2002, The Journal of Biological Chemistry.

[27]  Ernesto Carafoli,et al.  Calcium signaling: A tale for all seasons , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[28]  E. Stadtman,et al.  Mitochondria play no roles in Mn(II)-induced apoptosis in HeLa cells , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[29]  K. Gunter,et al.  Mitochondrial calcium transport: mechanisms and functions. , 2000, Cell calcium.

[30]  J. Martinou,et al.  Mitochondria as the central control point of apoptosis. , 2000, Trends in cell biology.

[31]  A. Sodhi,et al.  Mechanism of thymocyte apoptosis induced by serum of tumor-bearing host: the molecular events involved and their inhibition by thymosin alpha-1. , 2000, International journal of immunopharmacology.

[32]  B. T. Storey,et al.  Determination of the intracellular dissociation constant, KD, of the Fluo‐3 · Ca2+ complex in mouse sperm for use in estimating intracellular Ca2+ concentrations , 1999, Molecular reproduction and development.

[33]  W. Fiers,et al.  The 55-kDa Tumor Necrosis Factor Receptor Induces Clustering of Mitochondria through Its Membrane-proximal Region* , 1998, The Journal of Biological Chemistry.

[34]  B. Hille,et al.  Mitochondrial Participation in the Intracellular Ca2+ Network , 1997, The Journal of cell biology.

[35]  B. Hille,et al.  Dominant Role of Mitochondria in Clearance of Large Ca2+ Loads from Rat Adrenal Chromaffin Cells , 1996, Neuron.

[36]  K. Gunter,et al.  Transport of calcium by mitochondria , 1994, Journal of bioenergetics and biomembranes.

[37]  A. Surolia,et al.  A23187—Channel behaviour: Fluorescence study , 1994, Journal of Biosciences.

[38]  N. Holbrook,et al.  Calcium ionophore A23187 induces expression of the growth arrest and DNA damage inducible CCAAT/enhancer-binding protein (C/EBP)-related gene, gadd153. Ca2+ increases transcriptional activity and mRNA stability. , 1992, The Journal of biological chemistry.

[39]  M. Clarke,et al.  Inhibition of mitochondrial calcium ion transport by an oxo-bridged dinuclear ruthenium ammine complex. , 1991, Biochemistry.

[40]  T. Gunter,et al.  Mechanisms by which mitochondria transport calcium. , 1990, The American journal of physiology.

[41]  S. Balasubramanian,et al.  Aggregation of calcium ionophore (A23187) in phospholipid vesicles. , 1989, Biochemical and biophysical research communications.

[42]  U. Kaupp,et al.  Calcium-hydrogen exchange in isolated bovine rod outer segments. , 1985, Biochemistry.

[43]  M. Kolber,et al.  Fluorescence study of the divalent cation-transport mechanism of ionophore A23187 in phospholipid membranes. , 1981, Biophysical journal.

[44]  G. Weissmann,et al.  Phosphatidate and oxidized fatty acids are calcium ionophores. Studies employing arsenazo III in liposomes. , 1981, The Journal of biological chemistry.

[45]  J. Westhead.  Semiautomated Turbidimetric Bioassay for the Ionophore A23187 , 1977, Antimicrobial Agents and Chemotherapy.

[46]  N. D. Jones,et al.  The structure of the calcium complex of A23187, a divalent cation ionophore antibiotic. , 1976, The Journal of antibiotics.

[47]  K. Reed,et al.  A low molecular weight ruthenium complex inhibitory to mitochondrial Ca2+ transport , 1974, FEBS letters.

[48]  J. Vanderkooi,et al.  Physical properties of biological membranes determined by the fluorescence of the calcium ionophore A23187. , 1974, Archives of biochemistry and biophysics.

[49]  N. D. Jones,et al.  Letter: The structure of A23187, a divalent cation ionophore. , 1974, Journal of the American Chemical Society.

[50]  H. Lardy,et al.  A23187: a divalent cation ionophore. , 1972, The Journal of biological chemistry.

[51]  A. Caswell,et al.  Kinetics of transport of divalent cations across sarcoplasmic reticulum vesicles induced by ionophores. , 1972, Biochemical and biophysical research communications.

[52]  C. Moore,et al.  Specific inhibition of mitochondrial Ca++ transport by ruthenium red. , 1971, Biochemical and biophysical research communications.

[53]  D. Brewster,et al.  Trends in cancer incidence and mortality in Scotland: description and possible explanations. , 1998, British Journal of Cancer.

[54]  Alderley Park,et al.  United Kingdom Co-ordinating Committee on Cancer Research (UKCCCR) Guidelines for the Welfare of Animals in Experimental Neoplasia (Second Edition). , 1998, British Journal of Cancer.

[55]  D. Housman,et al.  Calcium ionophore, A23187, induces commitment to differentiation but inhibits the subsequent expression of erythroid genes in murine erythroleukemia cells. , 1991, Blood.

[56]  J. W. Paschal,et al.  The biosynthesis of antibiotic A23187 , 1983 .

[57]  J. Puskin,et al.  A fluorescence study of A23187 interaction with phospholipid vesicles. , 1981, Archives of biochemistry and biophysics.