Using Enterprise Miner TM to Explore and Exploit Drug Discovery Data

One of the biggest challenges in modern pharmaceutical drug discovery is the effective management and exploitation of research data. How can one find those relatively small nuggets of knowledge buried in the great morass of data being generated by High Throughput Screening systems? One potential answer is by using Enterprise MinerTM software! This talk will describe how it can be used to find structural features of potential drug molecules that appear to effect interesting (and useful) biological activity. It will be shown how one can use Enterprise MinerTM even at a very basic level to uncover potentially useful relationships that can be exploited to more rapidly find new therapeutic candidates. Special issues with respect to how to mathematically describe chemical structures will also be addressed. This talk is geared towards SAS users at the beginning to intermediate skill level.