Protective Effect of Quercetin in LPS-Induced Murine Acute Lung Injury Mediated by cAMP-Epac Pathway
暂无分享,去创建一个
Ya-jun Li | Xue-feng Wang | Shun-de Song | Zhengqiang Hu | Chun-guang Yan | Hui-Fang Tang | Zhe-wen Zhang | Zi-gang Li
[1] Laila M Fadda,et al. Pulmonary prophylactic impact of melatonin and/or quercetin: A novel therapy for inflammatory hypoxic stress in rats , 2017, Acta pharmaceutica.
[2] Xiao‐Yu Hu,et al. Quercetin ameliorates paclitaxel-induced neuropathic pain by stabilizing mast cells, and subsequently blocking PKCε-dependent activation of TRPV1 , 2016, Acta Pharmacologica Sinica.
[3] Z. Lv,et al. Protective effect of quercetin on acute lung injury in rats with sepsis and its influence on ICAM-1 and MIP-2 expression. , 2016, Genetics and molecular research : GMR.
[4] M. Balaan,et al. Acute Respiratory Distress Syndrome , 2016, Critical care nursing quarterly.
[5] U. Sener,et al. The Effects of Quercetin on Acute Lung Injury and Biomarkers of Inflammation and Oxidative Stress in the Rat Model of Sepsis , 2016, Inflammation.
[6] Á. Simonyi,et al. Quercetin Attenuates Inflammatory Responses in BV-2 Microglial Cells: Role of MAPKs on the Nrf2 Pathway and Induction of Heme Oxygenase-1 , 2015, PloS one.
[7] S. Cuzzocrea,et al. Protective effect of polyphenols in an inflammatory process associated with experimental pulmonary fibrosis in mice , 2015, British Journal of Nutrition.
[8] Ri-hong Huang,et al. Quercetin protects against lipopolysaccharide-induced acute lung injury in rats through suppression of inflammation and oxidative stress , 2015, Archives of medical science : AMS.
[9] Na Ye,et al. Biochemical and Pharmacological Characterizations of ESI-09 Based EPAC Inhibitors: Defining the ESI-09 “Therapeutic Window” , 2015, Scientific Reports.
[10] G. Forlani,et al. Quercetin and quercetin-3-O-glucoside interact with different components of the cAMP signaling cascade in human retinal pigment epithelial cells. , 2015, Life sciences.
[11] T. Kawabe,et al. Protective effects of intratracheally administered quercetin on lipopolysaccharide-induced acute lung injury , 2014, Respiratory Research.
[12] Hao Li,et al. Protective effect of quercetin on lipopolysaccharide-induced acute lung injury in mice by inhibiting inflammatory cell influx , 2014, Experimental biology and medicine.
[13] O. Salis,et al. The therapeutic effects of anti-oxidant and anti-inflammatory drug quercetin on aspiration-induced lung injury in rats , 2014, Journal of Molecular Histology.
[14] E. Taşlıdere,et al. Protective effects of melatonin and quercetin on experimental lung injury induced by carbon tetrachloride in rats , 2014, Experimental lung research.
[15] P. Boor,et al. Exchange protein directly activated by cAMP plays a critical role in bacterial invasion during fatal rickettsioses , 2013, Proceedings of the National Academy of Sciences.
[16] H. Rehmann. Epac-Inhibitors: Facts and Artefacts , 2013, Scientific Reports.
[17] S. Saponara,et al. Quercetin relaxes rat tail main artery partly via a PKG‐mediated stimulation of KCa1.1 channels , 2013, Acta physiologica.
[18] U. Kukongviriyapan,et al. Preventive and therapeutic effects of quercetin on lipopolysaccharide-induced oxidative stress and vascular dysfunction in mice. , 2012, Canadian journal of physiology and pharmacology.
[19] Buwei Yu,et al. Differential Roles of PKA and Epac on the Production of Cytokines in the Endotoxin-Stimulated Primary Cultured Microglia , 2011, Journal of Molecular Neuroscience.
[20] S. Pyo,et al. ROS/Epac1-mediated Rap1/NF-kappaB activation is required for the expression of BAFF in Raw264.7 murine macrophages. , 2011, Cellular signalling.
[21] T. Kawabe,et al. Attenuation of transforming growth factor-β-stimulated collagen production in fibroblasts by quercetin-induced heme oxygenase-1. , 2011, American journal of respiratory cell and molecular biology.
[22] C. Bai,et al. The value of the lipopolysaccharide-induced acute lung injury model in respiratory medicine , 2010, Expert review of respiratory medicine.
[23] Jae Ho Park,et al. Protective effect of quercetin against paraquat-induced lung injury in rats. , 2010, Life sciences.
[24] A. Birukova,et al. Rac GTPase is a hub for protein kinase A and Epac signaling in endothelial barrier protection by cAMP. , 2010, Microvascular research.
[25] J. Auchampach,et al. Adenosine Suppresses Lipopolysaccharide-Induced Tumor Necrosis Factor-α Production by Murine Macrophages through a Protein Kinase A- and Exchange Protein Activated by cAMP-Independent Signaling Pathway , 2009, Journal of Pharmacology and Experimental Therapeutics.
[26] T. Seyama,et al. Effects of hyperin, isoquercitrin and quercetin on lipopolysaccharide‐induced nitrite production in rat peritoneal macrophages , 2008, Phytotherapy research : PTR.
[27] K. Racké,et al. Role of Epac1 in mediating anti-proliferative effects of prostanoid EP2 receptors and cAMP in human lung fibroblasts , 2008, Naunyn-Schmiedeberg's Archives of Pharmacology.
[28] Elena Alekseeva,et al. Epac/Rap and PKA are novel mechanisms of ANP‐induced Rac‐mediated pulmonary endothelial barrier protection , 2008, Journal of cellular physiology.
[29] D. Lee,et al. Quercetin augments TRAIL-induced apoptotic death: involvement of the ERK signal transduction pathway. , 2008, Biochemical pharmacology.
[30] S. Døskeland,et al. Cyclic nucleotide analogs as probes of signaling pathways , 2008, Nature Methods.
[31] S. Peters,et al. Alterations in vasodilator-stimulated phosphoprotein (VASP) phosphorylation: associations with asthmatic phenotype, airway inflammation and β2-agonist use , 2006, Respiratory research.
[32] Hui-Lin Huang,et al. Inhibitory effects of flavonoids on phosphodiesterase isozymes from guinea pig and their structure-activity relationships. , 2004, Biochemical pharmacology.
[33] Sheng-Nan Wu,et al. Differential effects of quercetin, a natural polyphenolic flavonoid, on L‐Type calcium current in pituitary tumor (GH3) cells and neuronal NG108‐15 cells , 2003, Journal of cellular physiology.
[34] L. Luo,et al. Rac GTPases control axon growth, guidance and branching , 2002, Nature.
[35] D. Koop,et al. Effects of Ginkgo biloba extract (EGb 761) and quercetin on lipopolysaccharide-induced release of nitric oxide. , 2001, Chemico-biological interactions.
[36] N. Voelkel,et al. Dibutyryl-cAMP blocks endotoxin-induced lung injury in rats. , 1989, The American review of respiratory disease.
[37] J. Cazenave,et al. Role of cyclic AMP in the inhibition of human platelet aggregation by quercetin, a flavonoid that potentiates the effect of prostacyclin. , 1982, Biochemical pharmacology.
[38] D. Priebat,et al. Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. , 1982, The Journal of investigative dermatology.
[39] Juan Zhang,et al. The critical role of quercetin in autophagy and apoptosis in HeLa cells , 2015, Tumor Biology.
[40] Jian Cheng,et al. Preventive and therapeutic effects of quercetin on experimental radiation induced lung injury in mice. , 2015, Asian Pacific journal of cancer prevention : APJCP.