Fear conditioning and extinction across development: Evidence from human studies and animal models

[1]  Monique Ernst,et al.  Response to learned threat: An FMRI study in adolescent and adult anxiety. , 2013, The American journal of psychiatry.

[2]  B. Casey,et al.  The Teenage Brain , 2013 .

[3]  Todd A. Hare,et al.  A Developmental Shift from Positive to Negative Connectivity in Human Amygdala–Prefrontal Circuitry , 2013, The Journal of Neuroscience.

[4]  Greg Hajcak,et al.  Comparing electric shock and a fearful screaming face as unconditioned stimuli for fear learning. , 2012, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[5]  D. Pine,et al.  The development of fear learning and generalization in 8-13 year-olds. , 2012, Developmental psychobiology.

[6]  Catherine A. Hartley,et al.  Altered fear learning across development in both mouse and human , 2012, Proceedings of the National Academy of Sciences.

[7]  R. Sullivan,et al.  The Development and Neurobiology of Infant Attachment and Fear , 2012, Developmental Neuroscience.

[8]  S. Lissek.  TOWARD AN ACCOUNT OF CLINICAL ANXIETY PREDICATED ON BASIC, NEURALLY MAPPED MECHANISMS OF PAVLOVIAN FEAR‐LEARNING: THE CASE FOR CONDITIONED OVERGENERALIZATION , 2012, Depression and anxiety.

[9]  E. Phelps.  Emotion and cognition: insights from studies of the human amygdala. , 2006, Annual review of psychology.

[10]  Bruce Fischl,et al.  Brain structure correlates of individual differences in the acquisition and inhibition of conditioned fear. , 2011, Cerebral cortex.

[11]  D. Pine,et al.  How do social fears in adolescence develop? Fear conditioning shapes attention orienting to social threat cues , 2011, Cognition & emotion.

[12]  Stephen Maren,et al.  Seeking a Spotless Mind: Extinction, Deconsolidation, and Erasure of Fear Memory , 2011, Neuron.

[13]  J. Kim,et al.  Immunohistochemical analyses of long-term extinction of conditioned fear in adolescent rats. , 2011, Cerebral cortex.

[14]  E. Leibenluft,et al.  Distinct neural signatures of threat learning in adolescents and adults , 2011, Proceedings of the National Academy of Sciences.

[15]  C. Grillon,et al.  Development of anxiety: the role of threat appraisal and fear learning , 2011, Depression and anxiety.

[16]  J. Kim,et al.  Impaired Extinction Retention in Adolescent Rats: Effects of D-Cycloserine , 2010, Neuropsychopharmacology.

[17]  Francisco Sotres-Bayon,et al.  Prefrontal control of fear: more than just extinction , 2010, Current Opinion in Neurobiology.

[18]  J. Kim,et al.  New Findings on Extinction of Conditioned Fear Early in Development: Theoretical and Clinical Implications , 2010, Biological Psychiatry.

[19]  R. Richardson,et al.  Ontogeny of Fear Conditioning , 2009 .

[20]  Andreas Lüthi,et al.  Perineuronal Nets Protect Fear Memories from Erasure , 2009, Science.

[21]  J. Kim,et al.  Fear Extinction across Development: The Involvement of the Medial Prefrontal Cortex as Assessed by Temporary Inactivation and Immunohistochemistry , 2009, The Journal of Neuroscience.

[22]  R. Richardson,et al.  A developmental dissociation in compound summation following extinction , 2009, Neurobiology of Learning and Memory.

[23]  V. Arolt,et al.  Human Fear Conditioning and Extinction in Neuroimaging: A Systematic Review , 2009, PloS one.

[24]  Karine Sergerie,et al.  The role of the amygdala in emotional processing: A quantitative meta-analysis of functional neuroimaging studies , 2008, Neuroscience & Biobehavioral Reviews.

[25]  D. Neumann,et al.  The use of an unpleasant sound unconditional stimulus in an aversive conditioning procedure with 8- to 11-year-old children , 2008, Biological Psychology.

[26]  Ellen Leibenluft,et al.  A Developmental Examination of Amygdala Response to Facial Expressions , 2008, Journal of Cognitive Neuroscience.

[27]  M. Craske,et al.  Is aversive learning a marker of risk for anxiety disorders in children? , 2008, Behaviour research and therapy.

[28]  Gang Chen,et al.  Contextual Fear Conditioning in Humans: Cortical-Hippocampal and Amygdala Contributions , 2008, The Journal of Neuroscience.

[29]  A. David,et al.  Predictors of amygdala activation during the processing of emotional stimuli: A meta-analysis of 385 PET and fMRI studies , 2008, Brain Research Reviews.

[30]  D. Neumann,et al.  The use of an unpleasant sound as the unconditional stimulus in aversive Pavlovian conditioning experiments that involve children and adolescent participants , 2008, Behavior research methods.

[31]  R. F. Westbrook,et al.  The basolateral amygdala is necessary for learning but not relearning extinction of context conditioned fear. , 2008, Learning & memory.

[32]  Alan C. Evans,et al.  Neurodevelopmental Trajectories of the Human Cerebral Cortex , 2008, The Journal of Neuroscience.

[33]  J. Kim,et al.  The Effect of Temporary Amygdala Inactivation on Extinction and Reextinction of Fear in the Developing Rat: Unlearning as a Potential Mechanism for Extinction Early in Development , 2008, The Journal of Neuroscience.

[34]  J. Grafman,et al.  Focal brain damage protects against post-traumatic stress disorder in combat veterans , 2008, Nature Neuroscience.

[35]  J. Kim,et al.  The effect of the NMDA receptor antagonist MK-801 on the acquisition and extinction of learned fear in the developing rat. , 2007, Learning & memory.

[36]  S. Rauch,et al.  Recall of Fear Extinction in Humans Activates the Ventromedial Prefrontal Cortex and Hippocampus in Concert , 2007, Biological Psychiatry.

[37]  J. Kim,et al.  A developmental dissociation in reinstatement of an extinguished fear response in rats , 2007, Neurobiology of Learning and Memory.

[38]  J. Kim,et al.  A developmental dissociation of context and GABA effects on extinguished fear in rats. , 2007, Behavioral neuroscience.

[39]  G. Quirk,et al.  Activity in Prelimbic Cortex Is Necessary for the Expression of Learned, But Not Innate, Fears , 2007, The Journal of Neuroscience.

[40]  O. Lipp,et al.  Evidence for retarded extinction of aversive learning in anxious children. , 2006, Behaviour research and therapy.

[41]  Nikolaus Weiskopf,et al.  Context-Dependent Human Extinction Memory Is Mediated by a Ventromedial Prefrontal and Hippocampal Network , 2006, The Journal of Neuroscience.

[42]  K. Lattal,et al.  9YExtinction: Does It or Doesn’t It? The Requirement of Altered Gene Activity and New Protein Synthesis , 2006, Biological Psychiatry.

[43]  David L. Neumann,et al.  The use of an unpleasant sound as an unconditional stimulus in a human aversive Pavlovian conditioning procedure , 2006, Biological Psychology.

[44]  M. Delgado,et al.  Extending animal models of fear conditioning to humans , 2006, Biological Psychology.

[45]  S. Durston,et al.  From behavior to cognition to the brain and back: what have we learned from functional imaging studies of attention deficit hyperactivity disorder? , 2006, The American journal of psychiatry.

[46]  Uwe Runge,et al.  Fear Conditioning following Unilateral Temporal Lobectomy: Dissociation of Conditioned Startle Potentiation and Autonomic Learning , 2005, The Journal of Neuroscience.

[47]  G. Hasler,et al.  Major depression predicts an increase in long-term body weight variability in young adults. , 2005, Obesity research.

[48]  C. Grillon,et al.  Classical fear conditioning in the anxiety disorders: a meta-analysis. , 2005, Behaviour research and therapy.

[49]  R. Morris,et al.  Differential Effects of Lesions of the Amygdala and Prefrontal Cortex on Recognizing Facial Expressions of Complex Emotions , 2005, Journal of Cognitive Neuroscience.

[50]  Bruce Fischl,et al.  Thickness of ventromedial prefrontal cortex in humans is correlated with extinction memory. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[51]  M. Höfler,et al.  Longitudinal course of posttraumatic stress disorder and posttraumatic stress disorder symptoms in a community sample of adolescents and young adults. , 2005, The American journal of psychiatry.

[52]  M. Keller,et al.  Influence of psychiatric comorbidity on recovery and recurrence in generalized anxiety disorder, social phobia, and panic disorder: a 12-year prospective study. , 2005, The American journal of psychiatry.

[53]  L. Steinberg.  Cognitive and affective development in adolescence , 2005, Trends in Cognitive Sciences.

[54]  Michael Davis,et al.  Regulation of Gephyrin and GABAA Receptor Binding within the Amygdala after Fear Acquisition and Extinction , 2005, The Journal of Neuroscience.

[55]  Joseph E LeDoux,et al.  Extinction Learning in Humans Role of the Amygdala and vmPFC , 2004, Neuron.

[56]  R. Dolan,et al.  Human orbitofrontal cortex mediates extinction learning while accessing conditioned representations of value , 2004, Nature Neuroscience.

[57]  G. Quirk,et al.  Delayed recall of fear extinction in rats with lesions of ventral medial prefrontal cortex. , 2004, Learning & memory.

[58]  M. Bouton.  Context and behavioral processes in extinction. , 2004, Learning & memory.

[59]  Stephen Maren,et al.  Factors regulating the effects of hippocampal inactivation on renewal of conditional fear after extinction. , 2004, Learning & memory.

[60]  E. Stein,et al.  Amygdala and hippocampal activity during acquisition and extinction of human fear conditioning , 2004, Cognitive, affective & behavioral neuroscience.

[61]  A. Delamater.  Experimental extinction in Pavlovian conditioning: Behavioural and neuroscience perspectives: , 2004 .

[62]  S. Moriceau,et al.  Unique Neural Circuitry for Neonatal Olfactory Learning , 2004, The Journal of Neuroscience.

[63]  S. Royer,et al.  Bidirectional synaptic plasticity in intercalated amygdala neurons and the extinction of conditioned fear responses , 2002, Neuroscience.

[64]  M. Bouton.  Context, ambiguity, and unlearning: sources of relapse after behavioral extinction , 2002, Biological Psychiatry.

[65]  W. Silverman,et al.  Anxiety disorders in children and adolescents: Research, assessment and intervention , 2002, Behaviour Change.

[66]  E. Maguire,et al.  Methods for developmental studies of fear conditioning circuitry , 2001, Biological Psychiatry.

[67]  Stephen Maren,et al.  Hippocampal Inactivation Disrupts Contextual Retrieval of Fear Memory after Extinction , 2001, The Journal of Neuroscience.

[68]  G. Quirk,et al.  The Role of Ventromedial Prefrontal Cortex in the Recovery of Extinguished Fear , 2000, The Journal of Neuroscience.

[69]  R. Dolan,et al.  Classical fear conditioning in functional neuroimaging , 2000, Current Opinion in Neurobiology.

[70]  Joseph E LeDoux.  Emotion Circuits in the Brain , 2000 .

[71]  Karl J. Friston,et al.  Amygdala–Hippocampal Involvement in Human Aversive Trace Conditioning Revealed through Event-Related Functional Magnetic Resonance Imaging , 1999, The Journal of Neuroscience.

[72]  R. Adolphs,et al.  Normal recognition of emotional similarity between facial expressions following bilateral amygdala damage , 1999, Neuropsychologia.

[73]  R. F. Westbrook,et al.  Evidence that GABA transmission mediates context-specific extinction of learned fear , 1998, Psychopharmacology.

[74]  Joseph E LeDoux,et al.  Human Amygdala Activation during Conditioned Fear Acquisition and Extinction: a Mixed-Trial fMRI Study , 1998, Neuron.

[75]  Charles L. Wilson,et al.  Single Neuron Activity in Human Hippocampus and Amygdala during Recognition of Faces and Objects , 1997, Neuron.

[76]  F. Verhulst,et al.  The prevalence of DSM-III-R diagnoses in a national sample of Dutch adolescents. , 1997, Archives of general psychiatry.

[77]  Joseph E LeDoux,et al.  Impaired fear conditioning following unilateral temporal lobectomy in humans , 1995, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[78]  T. Achenbach.  Diagnosis, assessment, and comorbidity in psychosocial treatment research , 1995, Journal of abnormal child psychology.

[79]  R. Adolphs,et al.  Impaired recognition of emotion in facial expressions following bilateral damage to the human amygdala , 1994, Nature.

[80]  J. W. Rudy,et al.  Ontogeny of Contextual Fear Conditioning in Rats: Implications for Consolidation, Infantile Amnesia, and Hippocampal System Function , 1994 .

[81]  J. Hatch,et al.  Classical conditioning in children with attention deficit hyperactivity disorder (ADHD) and anxiety disorders: A test of Quay's model , 1993, Journal of abnormal child psychology.

[82]  K Merikangas,et al.  Fear-potentiated startle in humans: effects of anticipatory anxiety on the acoustic blink reflex. , 1991, Psychophysiology.

[83]  Michael Davis,et al.  Blocking of acquisition but not expression of conditioned fear-potentiated startle by NMDA antagonists in the amygdala , 1990, Nature.

[84]  H. Fitzgerald,et al.  Individual differences in infant orienting and autonomic conditioning. , 1974, Developmental psychobiology.

[85]  E. Sersen,et al.  CARDIAC CLASSICAL CONDITIONING AND REVERSAL IN THE MONGOLOID, ENCEPHALOPATHIC, AND NORMAL CHILD , 1970 .

[86]  M. Morrow,et al.  Differential GSR conditioning as a function of age. , 1969 .

[87]  J. Watson,et al.  Conditioned emotional reactions , 1920 .

[88]  G. Quirk,et al.  Fear extinction as a model for translational neuroscience: ten years of progress. , 2012, Annual review of psychology.

[89]  G. Quirk,et al.  Dissociable Roles of Prelimbic and Infralimbic Cortices, Ventral Hippocampus, and Basolateral Amygdala in the Expression and Extinction of Conditioned Fear , 2011, Neuropsychopharmacology.

[90]  Michael E Dawson,et al.  The development of skin conductance fear conditioning in children from ages 3 to 8 years. , 2010, Developmental science.

[91]  D. Neumann,et al.  Aversive Pavlovian conditioning in childhood anxiety disorders: impaired response inhibition and resistance to extinction. , 2009, Journal of abnormal psychology.

[92]  H. Flor,et al.  Context conditioning and extinction in humans: differential contribution of the hippocampus, amygdala and prefrontal cortex , 2009, The European journal of neuroscience.

[93]  N. Fox,et al.  Challenges in Developing Novel Treatments for Childhood Disorders: Lessons from Research on Anxiety , 2009, Neuropsychopharmacology.

[94]  G. Quirk,et al.  Neural Mechanisms of Extinction Learning and Retrieval , 2008, Neuropsychopharmacology.

[95]  Monique Ernst,et al.  Fear conditioning in adolescents with anxiety disorders: results from a novel experimental paradigm. , 2008, Journal of the American Academy of Child and Adolescent Psychiatry.

[96]  Timothy J Desmond,et al.  Behavioral / Systems / Cognitive Hippocampal Inactivation Disrupts the Acquisition and Contextual Encoding of Fear Extinction , 2005 .

[97]  G. Davey,et al.  Conditioning models of childhood anxiety , 2001 .

[98]  D. Pine,et al.  The risk for early-adulthood anxiety and depressive disorders in adolescents with anxiety and depressive disorders. , 1998, Archives of general psychiatry.