Qualitative models and fuzzy systems: an integrated approach for learning from data

This paper presents a method for the identification of the dynamics of non-linear systems by learning from data. The key idea which underlies our approach consists of the integration of qualitative modeling techniques with fuzzy logic systems. The resulting hybrid method exploits the a priori structural knowledge on the system to initialize a fuzzy inference procedure which determines, from the available experimental data, a functional approximation of the system dynamics that can be used as a reasonable predictor of the patient's future state. The major advantage which results from such an integrated framework lies in a significant improvement of both efficiency and robustness of identification methods based on fuzzy models which learn an input output relation from data. As a benchmark of our method, we have considered the problem of identifying the response to the insulin therapy from insulin-dependent diabetic patients: the results obtained are presented and discussed in the paper.

[1]  Xiao-Jun Zeng,et al.  Approximation accuracy analysis of fuzzy systems as function approximators , 1996, IEEE Trans. Fuzzy Syst..

[2]  Li-Xin Wang,et al.  Adaptive fuzzy systems and control - design and stability analysis , 1994 .

[3]  A M Albisser,et al.  Comparison of parametrized models for computer-based estimation of diabetic patient glucose response. , 1997, Medical informatics = Medecine et informatique.

[4]  M. Sugeno,et al.  Fuzzy Control of Model Car , 1985 .

[5]  Jyh-Shing Roger Jang,et al.  ANFIS: adaptive-network-based fuzzy inference system , 1993, IEEE Trans. Syst. Man Cybern..

[6]  Jerry M. Mendel,et al.  Fuzzy basis functions: comparisons with other basis functions , 1995, IEEE Trans. Fuzzy Syst..

[7]  E. Carson,et al.  A probabilistic approach to glucose prediction and insulin dose adjustment: description of metabolic model and pilot evaluation study. , 1994, Computer methods and programs in biomedicine.

[8]  A. John Mallinckrodt,et al.  Qualitative reasoning: Modeling and simulation with incomplete knowledge , 1994, at - Automatisierungstechnik.

[9]  D R Worthington The use of models in the self-management of insulin-dependent diabetes mellitus. , 1990, Computer methods and programs in biomedicine.

[10]  D Rodbard,et al.  Computer Simulation of Plasma Insulin and Glucose Dynamics After Subcutaneous Insulin Injection , 1989, Diabetes Care.

[11]  Giordano Lanzola,et al.  Qualitative models in medical diagnosis , 1990, Artif. Intell. Medicine.

[12]  Ewart R. Carson,et al.  The mathematical modeling of metabolic and endocrine systems : model formulation, identification, and validation , 1983 .

[13]  E D Lehmann,et al.  A physiological model of glucose-insulin interaction in type 1 diabetes mellitus. , 1992, Journal of biomedical engineering.

[14]  Tarun Khanna,et al.  Foundations of neural networks , 1990 .

[15]  M Stefanelli,et al.  A framework for building and simulating qualitative models of compartmental systems. , 1994, Computer methods and programs in biomedicine.