Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer’s disease
暂无分享,去创建一个
O. Andreassen | J. Haines | M. Pericak-Vance | G. Schellenberg | A. Dale | L. Sugrue | D. Bennett | L. McEvoy | R. Desikan | R. Sperling | B. Hyman | R. Mayeux | H. Feldman | J. Brewer | A. Witoelar | L. Farrer | M. Glymour | K. Yaffe | D. Posthuma | Celeste M. Karch | C. Hess | C. Fan | J. Yokoyama | W. Dillon | F. Elahi | C. Glastonbury | G. Rabinovici | I. Jansen | J. Savage | E. Mormino | C. Tan | I. Broce | Natalie Wen | Jennifer S. Yokoyama | B. Miller | B. Miller | C. Karch | Aree Witoelar | B. Miller | J. Haines | Iris J. Broce
[1] D. Llewellyn,et al. Which Risk Factors Causally Influence Dementia? A Systematic Review of Mendelian Randomization Studies , 2018, Journal of Alzheimer's disease : JAD.
[2] M. Farrall,et al. Lack of genetic support for shared aetiology of Coronary Artery Disease and Late-onset Alzheimer’s disease , 2018, Scientific Reports.
[3] C. Glass,et al. Oxidized Phospholipids are Proinflammatory and Proatherogenic in Hypercholesterolemic Mice , 2018, Nature.
[4] Samuel E. Jones,et al. Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry , 2018, bioRxiv.
[5] P. Visscher,et al. Meta-analysis of genome-wide association studies for height and body mass index in ∼700,000 individuals of European ancestry , 2018, bioRxiv.
[6] W. M. van der Flier,et al. Genetic meta-analysis identifies 9 novel loci and functional pathways for Alzheimer’s disease risk , 2018, bioRxiv.
[7] O. Andreassen,et al. Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies , 2018, PLoS medicine.
[8] John Hardy,et al. The genetic landscape of Alzheimer disease. , 2018, Handbook of clinical neurology.
[9] Quincy M. Samus,et al. Dementia prevention, intervention, and care , 2017, The Lancet.
[10] S. Larsson,et al. Modifiable pathways in Alzheimer’s disease: Mendelian randomisation analysis , 2017, British Medical Journal.
[11] Nick C Fox,et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease , 2017, Nature Genetics.
[12] J. Danesh,et al. Association analyses based on false discovery rate implicate new loci for coronary artery disease , 2017, Nature Genetics.
[13] Story C. Landis,et al. Preventing Cognitive Decline and Dementia: A Way Forward , 2017 .
[14] K. Hao,et al. A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease , 2017, Nature Neuroscience.
[15] Giovanni Malerba,et al. Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes , 2017, Nature Genetics.
[16] S. Hägg,et al. Genetic susceptibility to cardiovascular disease and risk of dementia , 2017, Translational Psychiatry.
[17] C A Emdin,et al. Apfeltyp erhöht Diabetes- und KHK-Risiko , 2017, DMW - Deutsche Medizinische Wochenschrift.
[18] Lilah M. Besser,et al. Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score , 2017, PLoS medicine.
[19] Kevin L. Boehme,et al. Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case–control study , 2017, PLoS medicine.
[20] Sekar Kathiresan,et al. Genetic Association of Waist-to-Hip Ratio With Cardiometabolic Traits, Type 2 Diabetes, and Coronary Heart Disease , 2017, JAMA.
[21] E. Karageorgiou,et al. Neuroimaging in Dementia , 2017, Seminars in Neurology.
[22] James A. Eddy,et al. Human whole genome genotype and transcriptome data for Alzheimer’s and other neurodegenerative diseases , 2016, Scientific Data.
[23] R. Mahley. Central Nervous System LipoproteinsHighlights , 2016 .
[24] O. Andreassen,et al. Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease. , 2016, JAMA neurology.
[25] Zhi-Sheng Jiang,et al. Imbalanced cholesterol metabolism in Alzheimer's disease. , 2016, Clinica chimica acta; international journal of clinical chemistry.
[26] Alison M. Goate,et al. Alzheimer’s Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci , 2016, PloS one.
[27] Magda Tsolaki,et al. A NOVEL ALZHEIMER DISEASE LOCUS LOCATED NEAR THE GENE ENCODING TAU PROTEIN , 2015, Molecular Psychiatry.
[28] Adult Changes in Thought Study Investigators,et al. Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses , 2015 .
[29] H. Stefánsson,et al. Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease , 2015, Circulation.
[30] Kevin L. Boehme,et al. Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study , 2015, PLoS medicine.
[31] Sara M. Willems,et al. The impact of low-frequency and rare variants on lipid levels , 2015, Nature Genetics.
[32] Thomas E. Nichols,et al. Common genetic variants influence human subcortical brain structures , 2015, Nature.
[33] M. Daly,et al. An Atlas of Genetic Correlations across Human Diseases and Traits , 2015, Nature Genetics.
[34] A Smith,et al. Genetic overlap between Alzheimer’s disease and Parkinson’s disease at the MAPT locus , 2015, Molecular Psychiatry.
[35] A. Levey,et al. Quantitative phosphoproteomics of Alzheimer's disease reveals cross‐talk between kinases and small heat shock proteins , 2015, Proteomics.
[36] Juan Zhang,et al. Cholesterol metabolism and homeostasis in the brain , 2015, Protein & Cell.
[37] K. Jellinger,et al. The overlap between vascular disease and Alzheimer’s disease - lessons from pathology , 2014, BMC Medicine.
[38] A. Singleton,et al. Genetic variability in the regulation of gene expression in ten regions of the human brain , 2014, Nature Neuroscience.
[39] Ian J. Deary,et al. Common genetic variants associated with cognitive performance identified using the proxy-phenotype method , 2014, Proceedings of the National Academy of Sciences.
[40] Francesco Bettella,et al. Shared common variants in prostate cancer and blood lipids. , 2014, International journal of epidemiology.
[41] Kristine Yaffe,et al. Potential for primary prevention of Alzheimer's disease: an analysis of population-based data , 2014, The Lancet Neurology.
[42] J. Nielsen,et al. Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics. , 2014, Molecular & cellular proteomics : MCP.
[43] O. Andreassen,et al. Boosting the power of schizophrenia genetics by leveraging new statistical tools. , 2014, Schizophrenia bulletin.
[44] Nick C Fox,et al. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease , 2013, Nature Genetics.
[45] Tanya M. Teslovich,et al. Discovery and refinement of loci associated with lipid levels , 2013, Nature Genetics.
[46] M. Peters,et al. Systematic identification of trans eQTLs as putative drivers of known disease associations , 2013, Nature Genetics.
[47] D. Rujescu,et al. Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate , 2013, PLoS genetics.
[48] M. McCarthy,et al. Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors. , 2013, American journal of human genetics.
[49] C. Reitz. Dyslipidemia and the Risk of Alzheimer’s Disease , 2013, Current Atherosclerosis Reports.
[50] K. Yaffe,et al. The projected effect of risk factor reduction on Alzheimer's disease prevalence , 2011, The Lancet Neurology.
[51] G. D. Paolo,et al. Linking lipids to Alzheimer's disease: cholesterol and beyond , 2011, Nature Reviews Cancer.
[52] Kristine Yaffe,et al. The Projected impact of risk factor reduction on Alzheimer's disease prevalence , 2011, Alzheimer's & Dementia.
[53] Saumitra Das,et al. Interplay between NS3 protease and human La protein regulates translation-replication switch of Hepatitis C virus , 2011, Scientific reports.
[54] G. D. Paolo,et al. Linking lipids to Alzheimer's disease: cholesterol and beyond , 2011, Nature Reviews Neuroscience.
[55] Howard J. Rosen,et al. Neuroimaging in Dementia , 2011, Neurotherapeutics.
[56] Frank W. Stearns. One Hundred Years of Pleiotropy: A Retrospective , 2010, Genetics.
[57] Anton P. Porsteinsson,et al. Meta-Analysis of Alzheimer's Disease Risk with Obesity, Diabetes, and Related Disorders , 2010, Biological Psychiatry.
[58] Børge G Nordestgaard,et al. Association of loss-of-function mutations in the ABCA1 gene with high-density lipoprotein cholesterol levels and risk of ischemic heart disease. , 2008, JAMA.
[59] Ellen M Wijsman,et al. Comprehensive analysis of APOE and selected proximate markers for late-onset Alzheimer's disease: patterns of linkage disequilibrium and disease/marker association. , 2007, Genomics.
[60] D. Sparks. Cholesterol metabolism and brain amyloidosis: evidence for a role of copper in the clearance of Abeta through the liver. , 2007, Current Alzheimer research.
[61] R. Mayeux,et al. Diabetes mellitus and risk of Alzheimer's disease and dementia with stroke in a multiethnic cohort. , 2001, American journal of epidemiology.
[62] F Mosteller,et al. Some Statistical Methods for Combining Experimental Results , 1990, International Journal of Technology Assessment in Health Care.