Epigenetic regulation in B-cell maturation and its dysregulation in autoimmunity
暂无分享,去创建一个
Q. Lu | Liwei Lu | Haijing Wu | Ming Zhao | K. Ma | Xiaohui Wang | Di Long | Yaxiong Deng | Yu Feng
[1] F. Shahram,et al. Histone variants expression in peripheral blood mononuclear cells of patients with rheumatoid arthritis , 2017, International journal of rheumatic diseases.
[2] I. Flórez,et al. The effect of adding metformin to insulin therapy for type 1 diabetes mellitus children: A systematic review and meta‐analysis , 2017, Pediatric diabetes.
[3] Q. Lu,et al. The epigenetic mechanism for discordance of autoimmunity in monozygotic twins. , 2017, Journal of autoimmunity.
[4] Jie Tian,et al. Proteasome inhibition suppresses Th17 cell generation and ameliorates autoimmune development in experimental Sjögren’s syndrome , 2017, Cellular & Molecular Immunology.
[5] Susan M. Schlenner,et al. Defective germinal center B-cell response and reduced arthritic pathology in microRNA-29a-deficient mice , 2017, Cellular and Molecular Life Sciences.
[6] M. Pellegrini,et al. Regulation of Marginal Zone B-Cell Differentiation by MicroRNA-146a , 2017, Front. Immunol..
[7] P. Tak,et al. Histone deacetylase 3 regulates the inflammatory gene expression programme of rheumatoid arthritis fibroblast-like synoviocytes , 2016, Annals of the rheumatic diseases.
[8] T. Xiao,et al. Innate immunity and inflammation , 2016, Cellular & Molecular Immunology.
[9] Q. Lu,et al. Dysregulation of Cell Death and Its Epigenetic Mechanisms in Systemic Lupus Erythematosus , 2016, Molecules.
[10] F. Bacha,et al. Insulin resistance, role of metformin and other non‐insulin therapies in pediatric type 1 diabetes , 2016, Pediatric diabetes.
[11] V. Chan,et al. The expression of Bcl-6 in circulating follicular helper-like T cells positively correlates with the disease activity in systemic lupus erythematosus. , 2016, Clinical immunology.
[12] Paul Flicek,et al. Increased DNA methylation variability in type 1 diabetes across three immune effector cell types , 2016, Nature Communications.
[13] E. Ballestar,et al. In vivo conditional deletion of HDAC7 reveals its requirement to establish proper B lymphocyte identity and development , 2016, The Journal of experimental medicine.
[14] Q. Lu,et al. The critical role of epigenetics in systemic lupus erythematosus and autoimmunity. , 2016, Journal of autoimmunity.
[15] A. Mangoni,et al. MicroRNA-155 influences B-cell function through PU.1 in rheumatoid arthritis , 2016, Nature Communications.
[16] G. Jena,et al. Valproic Acid Improves Glucose Homeostasis by Increasing Beta‐Cell Proliferation, Function, and Reducing its Apoptosis through HDAC Inhibition in Juvenile Diabetic Rat , 2016, Journal of biochemical and molecular toxicology.
[17] Q. Lu,et al. The key culprit in the pathogenesis of systemic lupus erythematosus: Aberrant DNA methylation. , 2016, Autoimmunity reviews.
[18] Huaxi Xu,et al. Olfactory ecto-mesenchymal stem cells possess immunoregulatory function and suppress autoimmune arthritis , 2015, Cellular and Molecular Immunology.
[19] B. Zhang,et al. Trichostatin A, an Inhibitor of Histone Deacetylase, Inhibits the Viability and Invasiveness of Hypoxic Rheumatoid Arthritis Fibroblast‐Like Synoviocytes via PI3K/Akt Signaling , 2016, Journal of biochemical and molecular toxicology.
[20] Dissecting Epigenetic Dysregulation of Primary Antibody Deficiencies , 2016, Journal of Clinical Immunology.
[21] A. Yoshimura,et al. Critical Link Between Epigenetics and Transcription Factors in the Induction of Autoimmunity: a Comprehensive Review , 2016, Clinical Reviews in Allergy & Immunology.
[22] X. Bian,et al. Genome-wide Analysis Identifies Bcl6-Controlled Regulatory Networks during T Follicular Helper Cell Differentiation. , 2016, Cell reports.
[23] Mike R. King. Commentary: Basic Research in HIV Vaccinology Is Hampered by Reductionist Thinking , 2016, Front. Immunol..
[24] N. Agmon-Levin,et al. Genetic Factors of Autoimmune Diseases , 2016, Journal of immunology research.
[25] W. Shi,et al. Blimp-1 controls plasma cell function through regulation of immunoglobulin secretion and the unfolded protein response , 2015, Nature Immunology.
[26] P. Casali,et al. Epigenetics of Peripheral B-Cell Differentiation and the Antibody Response , 2015, Front. Immunol..
[27] J. Wilkinson,et al. Histone deacetylase 1 regulates tissue destruction in rheumatoid arthritis. , 2015, Human molecular genetics.
[28] O. Elemento,et al. DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID. , 2015, Cell reports.
[29] D. Fairlie,et al. Inhibiting histone deacetylase 1 suppresses both inflammation and bone loss in arthritis. , 2015, Rheumatology.
[30] A. Díaz,et al. MicroRNAs miR-155 and miR-16 Decrease AID and E47 in B Cells from Elderly Individuals , 2015, The Journal of Immunology.
[31] C. Jorgensen,et al. MicroRNA Profiling of B Cell Subsets from Systemic Lupus Erythematosus Patients Reveals Promising Novel Biomarkers , 2015, International journal of molecular sciences.
[32] J. Tegnér,et al. Monozygotic twins discordant for common variable immunodeficiency reveal impaired DNA demethylation during naïve-to-memory B-cell transition , 2015, Nature Communications.
[33] Q. Lu,et al. The Real Culprit in Systemic Lupus Erythematosus: Abnormal Epigenetic Regulation , 2015, International journal of molecular sciences.
[34] B. Shen,et al. Cyr61 participates in the pathogenesis of rheumatoid arthritis by promoting proIL-1β production by fibroblast-like synoviocytes through an AKT-dependent NF-κB signaling pathway. , 2015, Clinical immunology.
[35] T. Chan,et al. The role of microRNA-1246 in the regulation of B cell activation and the pathogenesis of systemic lupus erythematosus , 2015, Clinical Epigenetics.
[36] S. Gay,et al. Epigenetics in rheumatoid arthritis , 2015, Current opinion in rheumatology.
[37] Lucia Migliore,et al. Obesity and diabetes: from genetics to epigenetics , 2014, Molecular Biology Reports.
[38] P. Casali,et al. Histone Deacetylase Inhibitors Upregulate B Cell microRNAs That Silence AID and Blimp-1 Expression for Epigenetic Modulation of Antibody and Autoantibody Responses , 2014, The Journal of Immunology.
[39] K. Good-Jacobson. Regulation of Germinal Center, B-Cell Memory, and Plasma Cell Formation by Histone Modifiers , 2014, Front. Immunol..
[40] L. MaroñasJiménez,et al. Systemic lupus erythematosus , 2014 .
[41] R. Hinman,et al. B cells and type 1 diabetes ...in mice and men. , 2014, Immunology letters.
[42] B. Strahl,et al. Interpreting the language of histone and DNA modifications. , 2014, Biochimica et biophysica acta.
[43] W. Klapper,et al. Genomic and epigenomic co-evolution in follicular lymphomas , 2014, Leukemia.
[44] P. Youinou,et al. DNA methylation modulates HRES1/p28 expression in B cells from patients with Lupus , 2014, Autoimmunity.
[45] G. Jena,et al. Protective role of sodium butyrate, a HDAC inhibitor on beta-cell proliferation, function and glucose homeostasis through modulation of p38/ERK MAPK and apoptotic pathways: study in juvenile diabetic rat. , 2014, Chemico-biological interactions.
[46] C. Galarza-Maldonado,et al. Diagnosis and classification of rheumatoid arthritis. , 2014, Journal of autoimmunity.
[47] B. Richardson,et al. Epigenetics in 2013: DNA methylation and miRNA—key roles in systemic autoimmunity , 2014, Nature Reviews Rheumatology.
[48] L. Ferrarini,et al. Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis. , 2013, The Journal of clinical investigation.
[49] P. Casali,et al. Combinatorial H3K9acS10ph histone modification in IgH locus S regions targets 14-3-3 adaptors and AID to specify antibody class-switch DNA recombination. , 2013, Cell reports.
[50] Yi Zhang,et al. TET enzymes, TDG and the dynamics of DNA demethylation , 2013, Nature.
[51] Sara A. Grimm,et al. DNA methylation profiling in human B cells reveals immune regulatory elements and epigenetic plasticity at Alu elements during B-cell activation , 2013, Genome research.
[52] P. Casali,et al. Epigenetics of the antibody response. , 2013, Trends in immunology.
[53] S. Boackle. Advances in lupus genetics , 2013, Current opinion in rheumatology.
[54] Miles Parkes,et al. Genetic insights into common pathways and complex relationships among immune-mediated diseases , 2013, Nature Reviews Genetics.
[55] Deyu Fang,et al. The class III histone deacetylase sirtuin 1 in immune suppression and its therapeutic potential in rheumatoid arthritis. , 2013, Journal of genetics and genomics = Yi chuan xue bao.
[56] Jie Dong,et al. MicroRNA-30a promotes B cell hyperactivity in patients with systemic lupus erythematosus by direct interaction with Lyn. , 2013, Arthritis and rheumatism.
[57] K. Reedquist,et al. The ascent of acetylation in the epigenetics of rheumatoid arthritis , 2013, Nature Reviews Rheumatology.
[58] Nesreen A. Hamad,et al. Accumulation of the FACT complex, as well as histone H3.3, serves as a target marker for somatic hypermutation , 2013, Proceedings of the National Academy of Sciences.
[59] Q. Lu,et al. The critical importance of epigenetics in autoimmunity. , 2013, Journal of autoimmunity.
[60] S. Raychaudhuri,et al. Genetics and epigenetics of rheumatoid arthritis , 2013, Nature Reviews Rheumatology.
[61] J. Tegnér,et al. Identification of novel markers in rheumatoid arthritis through integrated analysis of DNA methylation and microRNA expression. , 2013, Journal of autoimmunity.
[62] P. Pozzilli,et al. Epigenetics in autoimmune diseases with focus on type 1 diabetes , 2013, Diabetes/metabolism research and reviews.
[63] C. Hampe. B Cells in Autoimmune Diseases , 2012, Scientifica.
[64] Q. Lu,et al. Epigenetics, autoimmunity and hematologic malignancies: a comprehensive review. , 2012, Journal of autoimmunity.
[65] J. Whetstine,et al. Histone lysine methylation dynamics: establishment, regulation, and biological impact. , 2012, Molecular cell.
[66] Jacques Côté,et al. Histone phosphorylation , 2012, Epigenetics.
[67] M. Fraga,et al. DNA methylation: a promising landscape for immune system-related diseases. , 2012, Trends in genetics : TIG.
[68] S. Kasar,et al. Role of microRNA-15a in autoantibody production in interferon-augmented murine model of lupus. , 2012, Molecular immunology.
[69] T. Honjo,et al. The Histone Chaperone Spt6 Is Required for Activation-induced Cytidine Deaminase Target Determination through H3K4me3 Regulation* , 2012, The Journal of Biological Chemistry.
[70] R. Tooze,et al. BLIMP-1 and STAT3 Counterregulate MicroRNA-21 during Plasma Cell Differentiation , 2012, The Journal of Immunology.
[71] P. Casali,et al. Immunoglobulin class-switch DNA recombination: induction, targeting and beyond , 2012, Nature Reviews Immunology.
[72] T. Honjo,et al. The Histone Chaperone Spt 6 Is Required for Activation-induced Cytidine Deaminase Target Determination through H 3 K 4 me 3 Regulation * , 2012 .
[73] S. Kauppinen,et al. Silencing of microRNA-21 in vivo ameliorates autoimmune splenomegaly in lupus mice , 2011, EMBO molecular medicine.
[74] O. Elemento,et al. DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation. , 2011, Blood.
[75] Chuan He,et al. Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine , 2011, Science.
[76] Yang Wang,et al. Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA , 2011, Science.
[77] A. Maiti,et al. Thymine DNA Glycosylase Can Rapidly Excise 5-Formylcytosine and 5-Carboxylcytosine , 2011, The Journal of Biological Chemistry.
[78] F. Alt,et al. Epigenetic tethering of AID to the donor switch region during immunoglobulin class switch recombination , 2011, The Journal of experimental medicine.
[79] A. Mutirangura,et al. Hypomethylation of LINE-1 but not Alu in lymphocyte subsets of systemic lupus erythematosus patients. , 2011, Clinica chimica acta; international journal of clinical chemistry.
[80] P. Tak,et al. Inflammatory memories: is epigenetics the missing link to persistent stromal cell activation in rheumatoid arthritis? , 2011, Autoimmunity reviews.
[81] F. Fuks,et al. Regulation of mammalian DNA methyltransferases: a route to new mechanisms , 2011, EMBO reports.
[82] S. Gay,et al. MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis , 2011, Proceedings of the National Academy of Sciences.
[83] Fumiaki Sato,et al. MicroRNAs and epigenetics , 2011, The FEBS journal.
[84] A. Baccarelli,et al. The epigenetics of autoimmunity , 2011, Cellular and Molecular Immunology.
[85] Pierre Youinou,et al. Epigenetics and autoimmunity, with special emphasis on methylation. , 2011, The Keio journal of medicine.
[86] C. Simone,et al. Physical and Functional HAT/HDAC Interplay Regulates Protein Acetylation Balance , 2010, Journal of biomedicine & biotechnology.
[87] H. Allawi,et al. Epigenetic down-regulation of the tumor suppressor gene PRDM1/Blimp-1 in diffuse large B cell lymphomas: a potential role of the microRNA let-7. , 2010, The American journal of pathology.
[88] Yi Zhang,et al. Active DNA demethylation: many roads lead to Rome , 2010, Nature Reviews Molecular Cell Biology.
[89] R. Gay,et al. Epigenetics and rheumatoid arthritis: the role of SENP1 in the regulation of MMP-1 expression. , 2010, Journal of autoimmunity.
[90] P. Youinou,et al. Autoreactive B Cells and Epigenetics , 2010, Clinical reviews in allergy & immunology.
[91] K. Edwards,et al. Histone H2A and H2B Are Monoubiquitinated at AID-Targeted Loci , 2010, PloS one.
[92] Sabyasachi Das,et al. MicroRNA 125b inhibition of B cell differentiation in germinal centers. , 2010, International immunology.
[93] W. Filipowicz,et al. Regulation of mRNA translation and stability by microRNAs. , 2010, Annual review of biochemistry.
[94] M. Pellegrini,et al. Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency , 2010, Nature.
[95] R. Maul,et al. AID and somatic hypermutation. , 2010, Advances in immunology.
[96] F. Delbos,et al. Multiple layers of B cell memory with different effector functions , 2009, Nature Immunology.
[97] Xiaokun Li,et al. Induction of Foxp3 demethylation increases regulatory CD4+CD25+ T cells and prevents the occurrence of diabetes in mice , 2009, Journal of Molecular Medicine.
[98] J. Cambier,et al. Change you can B(cell)eive in: recent progress confirms a critical role for B cells in type 1 diabetes , 2009, Current opinion in endocrinology, diabetes, and obesity.
[99] A. Khamlichi,et al. Immunoglobulin switch μ sequence causes RNA polymerase II accumulation and reduces dA hypermutation , 2009, The Journal of experimental medicine.
[100] David R. Liu,et al. Conversion of 5-Methylcytosine to 5- Hydroxymethylcytosine in Mammalian DNA by the MLL Partner TET1 , 2009 .
[101] Dereje D. Jima,et al. Patterns of microRNA expression characterize stages of human B-cell differentiation. , 2009, Blood.
[102] Alain Saraux,et al. IL-6 Modulates CD5 Expression in B Cells from Patients with Lupus by Regulating DNA Methylation1 , 2009, The Journal of Immunology.
[103] M. Hochstrasser,et al. Origin and function of ubiquitin-like proteins , 2009, Nature.
[104] R. Gregory,et al. Many roads to maturity: microRNA biogenesis pathways and their regulation , 2009, Nature Cell Biology.
[105] P. Tak,et al. Targeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: should we keep our HATs on? , 2008, Arthritis research & therapy.
[106] G. Felsenfeld,et al. Analysis of intergenic transcription and histone modification across the human immunoglobulin heavy-chain locus , 2008, Proceedings of the National Academy of Sciences.
[107] C. Croce,et al. miR-181b negatively regulates activation-induced cytidine deaminase in B cells , 2008, The Journal of experimental medicine.
[108] R. Hardy,et al. Pax5 and Linker Histone H1 Coordinate DNA Methylation and Histone Modifications in the 3′ Regulatory Region of the Immunoglobulin Heavy Chain Locus , 2008, Molecular and Cellular Biology.
[109] T. Tuschl,et al. Tumorigenesis and Neoplastic Progression MicroRNA-Mediated Down-Regulation of PRDM 1 / Blimp-1 in Hodgkin / Reed-Sternberg Cells : A Potential Pathogenetic Lesion in Hodgkin Lymphomas , 2010 .
[110] Michel C Nussenzweig,et al. MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation. , 2008, Immunity.
[111] Vikki M. Weake,et al. Histone ubiquitination: triggering gene activity. , 2008, Molecular cell.
[112] Jing Wang,et al. Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes , 2008, Nature Immunology.
[113] Kyoko Ochiai,et al. Regulation of the plasma cell transcription factor Blimp-1 gene by Bach2 and Bcl6. , 2008, International immunology.
[114] K. Calame. MicroRNA-155 function in B Cells. , 2007, Immunity.
[115] Anton J. Enright,et al. microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells. , 2007, Immunity.
[116] W. Lutz,et al. p300 Protein Acetyltransferase Activity Suppresses Systemic Lupus Erythematosus-Like Autoimmune Disease in Mice1 , 2007, The Journal of Immunology.
[117] M. Busslinger,et al. Pax5: the guardian of B cell identity and function , 2007, Nature Immunology.
[118] Anton J. Enright,et al. Requirement of bic/microRNA-155 for Normal Immune Function , 2007, Science.
[119] N. Rajewsky,et al. Regulation of the Germinal Center Response by MicroRNA-155 , 2007, Science.
[120] M. Ouarzane,et al. Subversion of B lymphocyte tolerance by hydralazine, a potential mechanism for drug-induced lupus , 2007, Proceedings of the National Academy of Sciences.
[121] E. Lander,et al. The Mammalian Epigenome , 2007, Cell.
[122] G. Hughes,et al. Systemic lupus erythematosus , 2001, The Lancet.
[123] David G. Schatz,et al. Targeting of somatic hypermutation , 2006, Nature Reviews Immunology.
[124] L. Pasquier,et al. Orphanet Journal of Rare Diseases , 2006 .
[125] T. Spector,et al. Epigenetic differences arise during the lifetime of monozygotic twins. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[126] D. Schatz,et al. Histone modifications associated with somatic hypermutation. , 2005, Immunity.
[127] K. Calame,et al. Regulation of plasma-cell development , 2005, Nature Reviews Immunology.
[128] T. Jenuwein,et al. Histone hypomethylation is an indicator of epigenetic plasticity in quiescent lymphocytes , 2004, The EMBO journal.
[129] K. Wright,et al. PRDI-BF1 recruits the histone H3 methyltransferase G9a in transcriptional silencing , 2004, Nature Immunology.
[130] R. Gay,et al. The L1 Retroelement-related p40 Protein Induces p38δ MAP Kinase , 2004 .
[131] D. Bartel,et al. MicroRNAs Modulate Hematopoietic Lineage Differentiation , 2004, Science.
[132] A. Bottaro,et al. Activation of terminal B cell differentiation by inhibition of histone deacetylation. , 2003, Molecular immunology.
[133] Andrea Califano,et al. Transcriptional analysis of the B cell germinal center reaction , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[134] S. Khochbin,et al. Class II Histone Deacetylases Are Directly Recruited by BCL6 Transcriptional Repressor* , 2002, The Journal of Biological Chemistry.
[135] K. Calame,et al. Transcriptional Repression by Blimp-1 (PRDI-BF1) Involves Recruitment of Histone Deacetylase , 2000, Molecular and Cellular Biology.
[136] A. Naji,et al. B-Cells Are Required for the Initiation of Insulitis and Sialitis in Nonobese Diabetic Mice , 1997, Diabetes.