Ocular and systemic pharmacokinetics of lidocaine hydrochloride ophthalmic gel in rabbits after topical ocular administration

[1]  Chandralekha,et al.  A randomised comparison of lidocaine 2% gel and proparacaine 0.5% eye drops in paediatric squint surgery , 2013, Anaesthesia.

[2]  Chung Kang,et al.  Development of prilocaine gels for enhanced local anesthetic action , 2012, Archives of pharmacal research.

[3]  E. Reichel,et al.  A novel lidocaine hydrochloride ophthalmic gel for topical ocular anesthesia , 2010 .

[4]  D. Lam,et al.  Randomised controlled trial on the effectiveness of lidocaine gel vs tetracaine drops as the sole topical anaesthetic agent for primary pterygium surgery , 2009, Eye.

[5]  E. Reichel,et al.  Lidocaine hydrochloride gel for ocular anesthesia: results of a prospective, randomized study. , 2008, Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye.

[6]  H. Edelhauser,et al.  Barriers to Glaucoma Drug Delivery , 2008, Journal of glaucoma.

[7]  S. Underhill,et al.  Regional anaesthesia for intraocular surgery , 2005 .

[8]  M. Gremião,et al.  Colloidal carriers for ophthalmic drug delivery. , 2005, Current drug targets.

[9]  M. Soliman,et al.  Comparative clinical trial of topical anesthetic agents in cataract surgery: Lidocaine 2% gel, bupivacaine 0.5% drops, and benoxinate 0.4% drops , 2004, Journal of cataract and refractive surgery.

[10]  P. Blanchet,et al.  Local anesthesia before transrectal ultrasound guided prostate biopsy: comparison of 2 methods in a prospective, randomized clinical trial. , 2004, The Journal of urology.

[11]  H. Kafalı,et al.  Intrauterine lidocaine gel application for pain relief during and after hysterosalpingography , 2003, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

[12]  S. Koevary.  Pharmacokinetics of topical ocular drug delivery: potential uses for the treatment of diseases of the posterior segment and beyond. , 2003, Current drug metabolism.

[13]  S. Gelskey,et al.  A placebo-controlled multi-centred evaluation of an anaesthetic gel (Oraqix) for periodontal therapy. , 2003, Journal of clinical periodontology.

[14]  W. Green,et al.  Provision of anesthesia with single application of lidocaine 2% gel. , 1999, Journal of cataract and refractive surgery.

[15]  E. Kalso,et al.  Controlled Release of Lidocaine from Injectable Gels and Efficacy in Rat Sciatic Nerve Block , 1995, Pharmaceutical Research.

[16]  Tomi Järvinen,et al.  Ocular absorption following topical delivery , 1995 .

[17]  S. Chan,et al.  The effects of 2% lignocaine gel on incidence of retching with the use of the laryngeal mask airway , 1995, Anaesthesia.

[18]  A. Urtti,et al.  Minimizing systemic absorption of topically administered ophthalmic drugs. , 1993, Survey of ophthalmology.

[19]  Frederick W. Fraunfelder,et al.  Safety, efficacy, and patient acceptability of lidocaine hydrochloride ophthalmic gel as a topical ocular anesthetic for use in ophthalmic procedures. , 2009, Clinical ophthalmology.

[20]  F. Ciucci,et al.  Lidocaine 2% gel versus lidocaine 4% unpreserved drops for topical anesthesia in cataract surgery: a randomized controlled trial. , 2003, Ophthalmology.

[21]  D. Maurice.  The effect of the low blink rate in rabbits on topical drug penetration. , 1995, Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics.

[22]  A. Mitra,et al.  Ocular Drug Delivery , 1990 .