Computational design and selections for an engineered, thermostable terpene synthase
暂无分享,去创建一个
Jonathan Bronson | Jeffery G Saven | Gregory A Weiss | John Greaves | G. Weiss | J. Saven | J. E. Díaz | J. Greaves | Juan E Diaz | Kazuyoshi Kunishiro | K. Kunishiro | Chun-Shi Lin | Birte K Feld | Sara K Avrantinis | Sara K. Avrantinis | Chunlei Lin | B. Feld | J. Bronson
[1] B. Stoddard,et al. Computational Thermostabilization of an Enzyme , 2005, Science.
[2] W. K. Wilson,et al. Directed Evolution To Investigate Steric Control of Enzymatic Oxidosqualene Cyclization. An Isoleucine-to-Valine Mutation in Cycloartenol Synthase Allows Lanosterol and Parkeol Biosynthesis , 1999 .
[3] P. Bryan,et al. Crystal structure of calcium‐independent subtilisin BPN′ with restored thermal stability folded without the prodomain , 1998, Proteins.
[4] F. Arnold,et al. Evolving strategies for enzyme engineering. , 2005, Current opinion in structural biology.
[5] J. Noel,et al. Pre-steady-state study of recombinant sesquiterpene cyclases. , 1997, Biochemistry.
[6] B. Tidor,et al. Selection of horseradish peroxidase variants with enhanced enantioselectivity by yeast surface display. , 2007, Chemistry & biology.
[7] D N Woolfson,et al. Core-directed protein design. , 2001, Current opinion in structural biology.
[8] C. Poulter,et al. Prenyltransferase; determination of the binding mechanism and individual kinetic constants for farnesylpyrophosphate synthetase by rapid quench and isotope partitioning experiments. , 1981, Biochemistry.
[9] J. Cherry,et al. Directed evolution of industrial enzymes: an update. , 2003, Current opinion in biotechnology.
[10] Thomas E. Ferrin,et al. Designed divergent evolution of enzyme function , 2006, Nature.
[11] Joseph Chappell,et al. Structural Basis for Cyclic Terpene Biosynthesis by Tobacco 5‐epi‐Aristolochene Synthase , 1998 .
[12] S. Sidhu,et al. Phage display for selection of novel binding peptides. , 2000, Methods in enzymology.
[13] C. Starks,et al. Demonstration of Germacrene A as an Intermediate in 5-Epi-aristolochene Synthase Catalysis , 2000 .
[14] A. Zhong,et al. Quantifying β-Sheet Stability by Phage Display , 2002 .
[15] D. Cane,et al. [44] Monoterpene and sesquiterpene cyclases , 1985 .
[16] Roland L. Dunbrack,et al. Prediction of protein side-chain rotamers from a backbone-dependent rotamer library: a new homology modeling tool. , 1997, Journal of molecular biology.
[17] Hong Cheng,et al. De novo design of a single-chain diphenylporphyrin metalloprotein. , 2007, Journal of the American Chemical Society.
[18] Quantifying beta-sheet stability by phage display. , 2002, Journal of molecular biology.
[19] R. Sauer,et al. The structural stability of a protein is an important determinant of its proteolytic susceptibility in Escherichia coli. , 1989, The Journal of biological chemistry.
[20] J. Noel,et al. Identifying and manipulating structural determinates linking catalytic specificities in terpene synthases. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[21] J. Chappell,et al. Chapter ten The chemical wizardry of isoprenoid metabolism in plants , 2003 .
[22] Frances H. Arnold,et al. Directed evolution of a para-nitrobenzyl esterase for aqueous-organic solvents , 1996, Nature Biotechnology.
[23] F. Jurnak,et al. EF-Tu binding peptides identified, dissected, and affinity optimized by phage display. , 2003, Chemistry & biology.
[24] H Kono,et al. Statistical Theory for Protein Combinatorial Libraries , 2001 .
[25] Christopher M. Clouthier,et al. Directed evolution as a method to create enantioselective cyclohexanone monooxygenases for catalysis in Baeyer-Villiger reactions. , 2004, Angewandte Chemie.
[26] J. Chappell,et al. Molecular scaffolds for chemical wizardry: Learning nature's rules for terpene cyclases , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[27] Yawen Bai,et al. Selection of stably folded proteins by phage-display with proteolysis. , 2004, European journal of biochemistry.
[28] D. Cane. Enzymatic Formation of Sesquiterpenes , 1991 .
[29] J G Saven,et al. Statistical theory for protein combinatorial libraries. Packing interactions, backbone flexibility, and the sequence variability of a main-chain structure. , 2001, Journal of molecular biology.
[30] Yawen Bai,et al. Redesign of a four-helix bundle protein by phage display coupled with proteolysis and structural characterization by NMR and X-ray crystallography. , 2002, Journal of molecular biology.
[31] D N Woolfson,et al. Core-directed protein design. I. An experimental method for selecting stable proteins from combinatorial libraries. , 1999, Biochemistry.
[32] T. Kunkel. Rapid and efficient site-specific mutagenesis without phenotypic selection. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[33] D. Cane. Enzymic formation of sesquiterpenes , 1990 .
[34] J. Noel,et al. A single-vial analytical and quantitative gas chromatography-mass spectrometry assay for terpene synthases. , 2004, Analytical biochemistry.
[35] H. Suenaga,et al. Biphenyl Dioxygenases: Functional Versatilities and Directed Evolution , 2004, Journal of bacteriology.
[36] U. Singh,et al. A NEW FORCE FIELD FOR MOLECULAR MECHANICAL SIMULATION OF NUCLEIC ACIDS AND PROTEINS , 1984 .
[37] F. Arnold,et al. A structural view of evolutionary divergence. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[38] Hidetoshi Kono,et al. Computational design and characterization of a monomeric helical dinuclear metalloprotein. , 2003, Journal of molecular biology.
[39] Jeffery G. Saven,et al. Computational design of water-soluble analogues of the potassium channel KcsA , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[40] Linda A. Castle,et al. Discovery and Directed Evolution of a Glyphosate Tolerance Gene , 2004, Science.
[41] R. Burgess,et al. Purification of overproduced Escherichia coli RNA polymerase sigma factors by solubilizing inclusion bodies and refolding from Sarkosyl. , 1996, Methods in enzymology.
[42] Frances H. Arnold,et al. Diversifying Carotenoid Biosynthetic Pathways by Directed Evolution , 2005, Microbiology and Molecular Biology Reviews.
[43] F. Arnold,et al. Directed evolution of a thermostable esterase. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[44] A. Plückthun,et al. Selecting proteins with improved stability by a phage-based method , 1998, Nature Biotechnology.
[45] Vikas Nanda,et al. De novo design of a redox-active minimal rubredoxin mimic. , 2005, Journal of the American Chemical Society.
[46] J. Noel,et al. Biosynthetic potential of sesquiterpene synthases: alternative products of tobacco 5-epi-aristolochene synthase. , 2006, Archives of biochemistry and biophysics.
[47] D. Cane,et al. Pre-steady-state kinetic analysis of the trichodiene synthase reaction pathway. , 1997, Biochemistry.
[48] Dan S. Tawfik,et al. High-throughput screening of enzyme libraries: thiolactonases evolved by fluorescence-activated sorting of single cells in emulsion compartments. , 2005, Chemistry & biology.
[49] L. Overman,et al. Guanidine alkaloid analogs as inhibitors of HIV-1 Nef interactions with p53, actin, and p56lck. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[50] R. Croteau,et al. Cyclization Enzymes in the Biosynthesis of Monoterpenes, Sesquiterpenes, and Diterpenes , 2000 .
[51] J. Noel,et al. Structural basis for cyclic terpene biosynthesis by tobacco 5-epi-aristolochene synthase. , 1997, Science.
[52] Andreas Plückthun,et al. Selection based on the folding properties of proteins with ribosome display , 2003, FEBS letters.
[53] G. Winter,et al. Proteolytic selection for protein folding using filamentous bacteriophages. , 1998, Folding & design.