The administration to Indonesians of monosodium L-glutamate in Indonesian foods: an assessment of adverse reactions in a randomized double-blind, crossover, placebo-controlled study.

Monosodium L-glutamate (MSG) has been suggested to cause postprandial symptoms after the ingestion of Chinese or oriental meals. Therefore, we examined whether such symptoms could be elicited in Indonesians ingesting levels of MSG typically found in Indonesian cuisine. Healthy volunteers (n = 52) were treated with capsules of placebo or MSG (1.5 and 3.0 g/person) as part of a standardized Indonesian breakfast. The study used a rigorous, randomized, double-blind, crossover design. The occurrence of symptoms after MSG ingestion did not differ from that after consumption of the placebo.

[1]  D R Altman,et al.  Public perception of food allergy. , 1996, Environmental toxicology and pharmacology.

[2]  P. Dalton,et al.  Odor perception and beliefs about risk. , 1996, Chemical senses.

[3]  L. Tarasoff,et al.  Monosodium L-glutamate: a double-blind study and review. , 1993, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[4]  P. Lees-Haley,et al.  Biases in Perception and Reporting following a Perceived Toxic Exposure , 1992, Perceptual and motor skills.

[5]  V. Tanphaichitr,et al.  Postprandial responses to Thai foods with and without added monosodium L-glutamate , 1983 .

[6]  R. Kenney,et al.  Human susceptibility to oral monosodium L-glutamate. , 1972, The American journal of clinical nutrition.

[7]  R. Byck,et al.  Monosodium L-Glutamate: Its Pharmacology and Role in the Chinese Restaurant Syndrome , 1969, Science.

[8]  H. Schaumburg Chinese-restaurant syndrome. , 1968, The New England journal of medicine.