Hormone Signaling
暂无分享,去创建一个
[1] Zhuowei Wang,et al. Modulation of Circulating Leptin Levels by Its Soluble Receptor* , 2001, The Journal of Biological Chemistry.
[2] R. Kapur,et al. A Novel Mechanism of Cooperation between c-Kit and Erythropoietin Receptor , 2001, The Journal of Biological Chemistry.
[3] 美仁 長谷山. Phosphatidylinositol 3-Kinase Is Involved in the Protection of Primary Cultured Human Erythroid Precursor Cells From Apoptosis , 2001 .
[4] J. Flier,et al. SOCS3 Mediates Feedback Inhibition of the Leptin Receptor via Tyr985 * , 2000, The Journal of Biological Chemistry.
[5] A. Gewirtz,et al. PI-3k-Akt axis inhibits apoptosis in normal human megakaryoblasts and is efficiently activated by thrombopoietin , 2000 .
[6] A. Miyajima,et al. Thrombopoietin and interleukin-2 induce association of CRK with STAT5. , 2000, Biochemical and biophysical research communications.
[7] H. Sakamoto,et al. Mitogen-activated Protein Kinase Plays an Essential Role in the Erythropoietin-dependent Proliferation of CTLL-2 Cells* , 2000, The Journal of Biological Chemistry.
[8] G. Fantuzzi,et al. Leptin in the regulation of immunity, inflammation, and hematopoiesis , 2000, Journal of leukocyte biology.
[9] A. Yoshimura,et al. CIS3/SOCS-3 Suppresses Erythropoietin (EPO) Signaling by Binding the EPO Receptor and JAK2* , 2000, The Journal of Biological Chemistry.
[10] Y. Miyakawa,et al. Interferon-alpha directly represses megakaryopoiesis by inhibiting thrombopoietin-induced signaling through induction of SOCS-1. , 2000, Blood.
[11] L. Platanias,et al. Activation of the Akt/FKHRL1 pathway mediates the antiapoptotic effects of erythropoietin in primary human erythroid progenitors. , 2000, Biochemical and biophysical research communications.
[12] J. Ryan,et al. JNK and p38 are activated by erythropoietin (EPO) but are not induced in apoptosis following EPO withdrawal in EPO-dependent HCD57 cells. , 2000, Blood.
[13] M. Karin,et al. Requirement for p38α in Erythropoietin Expression A Role for Stress Kinases in Erythropoiesis , 2000, Cell.
[14] J. Schwartz,et al. The role of STAT proteins in growth hormone signaling , 2000, Oncogene.
[15] Alexander S. Banks,et al. Activation of Downstream Signals by the Long Form of the Leptin Receptor* , 2000, The Journal of Biological Chemistry.
[16] Christopher E. Rudd,et al. Lymphocyte signaling: Cbl sets the threshold for autoimmunity , 2000, Current Biology.
[17] F. Porteu,et al. A new feature of Mpl receptor: ligand-induced transforming activity in FRE rat fibroblasts , 2000, Oncogene.
[18] S. Klinken,et al. HS1 Interacts with Lyn and Is Critical for Erythropoietin-induced Differentiation of Erythroid Cells* , 2000, The Journal of Biological Chemistry.
[19] M. Ballmaier,et al. Thrombopoietin induces the generation of distinct Stat1, Stat3, Stat5a and Stat5b homo- and heterodimeric complexes with different kinetics in human platelets. , 2000, Experimental hematology.
[20] J. van der Kaay,et al. Essential Role of Phosphoinositide 3-Kinase in Leptin-inducedK ATP Channel Activation in the Rat CRI-G1 Insulinoma Cell Line* , 2000, The Journal of Biological Chemistry.
[21] B. Beattie,et al. The SH2 Inositol 5-Phosphatase Ship1 Is Recruited in an SH2-dependent Manner to the Erythropoietin Receptor* , 2000, The Journal of Biological Chemistry.
[22] J. Myklebust,et al. Protein kinase C-α isoform is involved in erythropoietin-induced erythroid differentiation of CD34+ progenitor cells from human bone marrow , 2000 .
[23] F. D. de Sauvage,et al. Role of the Distal Half of the c-Mpl Intracellular Domain in Control of Platelet Production by Thrombopoietin In Vivo , 2000, Molecular and Cellular Biology.
[24] C. Carter-Su,et al. SH2-B and SIRP: JAK2 binding proteins that modulate the actions of growth hormone. , 2000, Recent progress in hormone research.
[25] J. Herrington,et al. Role of the tyrosine kinase JAK2 in signal transduction by growth hormone , 2000, Pediatric Nephrology.
[26] R. Jaster,et al. Activation of STAT5 during EPO-directed suppression of apoptosis. , 2000, Cellular signalling.
[27] B. Druker,et al. Thrombopoietin-Induced Signal Transduction and Potentiation of Platelet Activation , 1999, Thrombosis and Haemostasis.
[28] B. Haye,et al. Erythropoietin Induces Glycosylphosphatidylinositol Hydrolysis , 1999, The Journal of Biological Chemistry.
[29] S. Gammeltoft,et al. Leptin stimulates glucose uptake in C2C12 muscle cells by activation of ERK2 , 1999, Molecular and Cellular Endocrinology.
[30] S. R. Datta,et al. Cellular survival: a play in three Akts. , 1999, Genes & development.
[31] N. Miyasaka,et al. CrkL Mediates Ras-dependent Activation of the Raf/ERK Pathway through the Guanine Nucleotide Exchange Factor C3G in Hematopoietic Cells Stimulated with Erythropoietin or Interleukin-3* , 1999, The Journal of Biological Chemistry.
[32] J. Flier,et al. The Role of SOCS-3 in Leptin Signaling and Leptin Resistance* , 1999, The Journal of Biological Chemistry.
[33] A. Yoshimura,et al. Thrombopoietin induces an SH2-containing protein, CIS1, which binds to Mpl: involvement of the ubiquitin proteosome pathway. , 1999, Experimental hematology.
[34] Paul J Hertzog,et al. SOCS1 Is a Critical Inhibitor of Interferon γ Signaling and Prevents the Potentially Fatal Neonatal Actions of this Cytokine , 1999, Cell.
[35] M. Kubo,et al. Suppression of STAT5 Functions in Liver, Mammary Glands, and T Cells in Cytokine-Inducible SH2-Containing Protein 1 Transgenic Mice , 1999, Molecular and Cellular Biology.
[36] Arun Sharma,et al. Engagement of Gab1 and Gab2 in Erythropoietin Signaling* , 1999, The Journal of Biological Chemistry.
[37] K. Kaushansky,et al. Thrombopoietin-induced activation of the mitogen-activated protein kinase (MAPK) pathway in normal megakaryocytes: role in endomitosis. , 1999, Blood.
[38] H. Lodish,et al. Fetal Anemia and Apoptosis of Red Cell Progenitors in Stat5a−/−5b−/− Mice A Direct Role for Stat5 in Bcl-XL Induction , 1999, Cell.
[39] T. Uchiyama,et al. Thrombopoietin potentiates agonist-stimulated activation of p38 mitogen-activated protein kinase in human platelets. , 1999, Biochemical and biophysical research communications.
[40] K. Kaushansky,et al. Thrombopoietin Signal Transduction Requires Functional JAK2, Not TYK2* , 1999, The Journal of Biological Chemistry.
[41] A. Yoshimura,et al. APS, an adaptor protein containing Pleckstrin homology (PH) and Src homology-2 (SH2) domains inhibits the JAK-STAT pathway in collaboration with c-Cbl , 1999, Leukemia.
[42] C. Lacombe,et al. Erythropoietin induces the tyrosine phosphorylation of GAB1 and its association with SHC, SHP2, SHIP, and phosphatidylinositol 3-kinase. , 1999, Blood.
[43] K. Kaushansky. Thrombopoietin and Hematopoietic Stem Cell Development , 1999, Annals of the New York Academy of Sciences.
[44] R. Jove,et al. Constitutive activation of the JAK2/STAT5 signal transduction pathway correlates with growth factor independence of megakaryocytic leukemic cell lines. , 1999, Blood.
[45] M. Eguchi,et al. Identification of mutations in the c-mpl gene in congenital amegakaryocytic thrombocytopenia. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[46] K. Kaushansky,et al. Thrombopoietin signal transduction: studies from cell lines and primary cells. , 1999, Methods.
[47] A. Yoshimura,et al. The JAK‐binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop , 1999, The EMBO journal.
[48] A. Miyajima,et al. Role of cytokine signaling molecules in erythroid differentiation of mouse fetal liver hematopoietic cells: functional analysis of signaling molecules by retrovirus-mediated expression. , 1999, Blood.
[49] I. Wilson,et al. Erythropoietin receptor activation by a ligand-induced conformation change. , 1999, Science.
[50] F. D. de Sauvage,et al. Permissive role of thrombopoietin and granulocyte colony-stimulating factor receptors in hematopoietic cell fate decisions in vivo. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[51] R. Jaster,et al. SHP1 Protein Tyrosine Phosphatase Negatively Modulates Erythroid Differentiation and Suppression of Apoptosis in J2E Erythroleukemic Cells , 1999, Biological chemistry.
[52] Stefan N. Constantinescu,et al. The Erythropoietin Receptor: Structure, Activation and Intracellular Signal Transduction , 1999, Trends in Endocrinology & Metabolism.
[53] F. Porteu,et al. Megakaryocyte growth and development factor-induced proliferation and differentiation are regulated by the mitogen-activated protein kinase pathway in primitive cord blood hematopoietic progenitors. , 1999, Blood.
[54] P. Mayeux,et al. Physical and Functional Interaction between p72 syk and Erythropoietin Receptor* , 1998, The Journal of Biological Chemistry.
[55] T. Uchiyama,et al. Thrombopoietin potentiates the protein-kinase-C-mediated activation of mitogen-activated protein kinase/ERK kinases and extracellular signal-regulated kinases in human platelets. , 1998, European journal of biochemistry.
[56] J. Ihle,et al. Signaling by the Cytokine Receptor Superfamily a , 1998, Annals of the New York Academy of Sciences.
[57] A. Yoshimura,et al. The CIS family: negative regulators of JAK-STAT signaling. , 1998, Cytokine & growth factor reviews.
[58] S. Feller,et al. Physiological signals and oncogenesis mediated through Crk family adapter proteins , 1998, Journal of cellular physiology.
[59] S. Shimamura,et al. Association of CrkL with STAT5 in hematopoietic cells stimulated by granulocyte-macrophage colony-stimulating factor or erythropoietin. , 1998, Biochemical and biophysical research communications.
[60] A. Yoshimura,et al. Proteasomes Regulate Erythropoietin Receptor and Signal Transducer and Activator of Transcription 5 (STAT5) Activation , 1998, The Journal of Biological Chemistry.
[61] F. Gouilleux,et al. A Sequence of the CIS Gene Promoter Interacts Preferentially with Two Associated STAT5A Dimers: a Distinct Biochemical Difference between STAT5A and STAT5B , 1998, Molecular and Cellular Biology.
[62] Y Nagata,et al. Activation of p38 MAP kinase and JNK but not ERK is required for erythropoietin-induced erythroid differentiation. , 1998, Blood.
[63] R. Gregory,et al. Erythropoietin receptor and STAT5-specific pathways promote SKT6 cell hemoglobinization. , 1998, Blood.
[64] J. Krosl,et al. The hyperresponsiveness of cells expressing truncated erythropoietin receptors is contingent on insulin-like growth factor-1 in fetal calf serum. , 1998, Blood.
[65] M. Souyri. Mpl: from an acute myeloproliferative virus to the isolation of the long sought thrombopoietin. , 1998, Seminars in hematology.
[66] T. Hirano,et al. Involvement of Prolonged Ras Activation in Thrombopoietin-Induced Megakaryocytic Differentiation of a Human Factor-Dependent Hematopoietic Cell Line , 1998, Molecular and Cellular Biology.
[67] P. Kelly,et al. Prolactin (PRL) and its receptor: actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice. , 1998, Endocrine reviews.
[68] G. Krystal,et al. Targeted disruption of SHIP leads to hemopoietic perturbations, lung pathology, and a shortened life span. , 1998, Genes & development.
[69] Michael P. Brown,et al. Stat5a and Stat5b Proteins Have Essential and Nonessential, or Redundant, Roles in Cytokine Responses , 1998, Cell.
[70] N. Stahl,et al. Enhancing leptin response by preventing SH2-containing phosphatase 2 interaction with Ob receptor. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[71] N. Miyasaka,et al. Lyn physically associates with the erythropoietin receptor and may play a role in activation of the Stat5 pathway. , 1998, Blood.
[72] A. Yoshimura,et al. Physiology and function of the erythropoietin receptor , 1998, Current opinion in hematology.
[73] A. Cumano,et al. Jak2 Deficiency Defines an EssentialDevelopmental Checkpoint in DefinitiveHematopoiesis , 1998, Cell.
[74] J. Marine,et al. Jak2 Is Essential for Signaling through a Variety of Cytokine Receptors , 1998, Cell.
[75] J. Flier,et al. Identification of SOCS-3 as a potential mediator of central leptin resistance. , 1998, Molecular cell.
[76] W. Vainchenker,et al. Protein kinase C mediates the mitogenic action of thrombopoietin in c-Mpl-expressing UT-7 cells , 1998 .
[77] H. Lodish,et al. Tyrosine Residues within the Intracellular Domain of the Erythropoietin Receptor Mediate Activation of AP-1 Transcription Factors* , 1998, The Journal of Biological Chemistry.
[78] H. Lodish,et al. The prolactin receptor rescues EpoR-/- erythroid progenitors and replaces EpoR in a synergistic interaction with c-kit. , 1998, Blood.
[79] B. Druker,et al. Erythropoietin induces tyrosine phosphorylation of Jak2, STAT5A, and STAT5B in primary cultured human erythroid precursors. , 1998, Blood.
[80] Y. Oka,et al. Leptin induces proliferation of pancreatic beta cell line MIN6 through activation of mitogen-activated protein kinase. , 1997, Biochemical and biophysical research communications.
[81] J. Flier,et al. Divergent Signaling Capacities of the Long and Short Isoforms of the Leptin Receptor* , 1997, The Journal of Biological Chemistry.
[82] S. Goff,et al. The Thrombopoietin Receptor Can Mediate Proliferation without Activation of the Jak-STAT Pathway , 1997, The Journal of experimental medicine.
[83] U Klingmüller,et al. The role of tyrosine phosphorylation in proliferation and maturation of erythroid progenitor cells--signals emanating from the erythropoietin receptor. , 1997, European journal of biochemistry.
[84] C. Lacombe,et al. Erythropoietin Induces the Tyrosine Phosphorylation of Insulin Receptor Substrate-2 , 1997, The Journal of Biological Chemistry.
[85] I. Dusanter-Fourt,et al. The structure, regulation and function of the Janus kinases (JAKs) and the signal transducers and activators of transcription (STATs). , 1997, European journal of biochemistry.
[86] I. Dusanter-Fourt,et al. Control of thrombopoietin-induced megakaryocytic differentiation by the mitogen-activated protein kinase pathway , 1997, Molecular and cellular biology.
[87] B. Schwartz,et al. Protein kinase C in erythroid and megakaryocytic differentiation: possible role in lineage determination. , 1997, Biochimica et biophysica acta.
[88] E. Nishida,et al. Activation of p38 MAP kinase pathway by erythropoietin and interleukin-3. , 1997, Blood.
[89] L. Tartaglia,et al. Leptin Receptor Action in Hepatic Cells* , 1997, The Journal of Biological Chemistry.
[90] H. Iwasaki,et al. Role of the vav Proto-oncogene Product (Vav) in Erythropoietin-mediated Cell Proliferation and Phosphatidylinositol 3-Kinase Activity* , 1997, The Journal of Biological Chemistry.
[91] H. Lodish,et al. The Prolactin Receptor and Severely Truncated Erythropoietin Receptors Support Differentiation of Erythroid Progenitors* , 1997, The Journal of Biological Chemistry.
[92] K. Chihara,et al. Leptin Induces Mitogen-activated Protein Kinase- dependent Proliferation of C3H10T1/2 Cells* , 1997, The Journal of Biological Chemistry.
[93] L. Yu-Lee. Molecular Actions of Prolactin in the Immune System , 1997, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.
[94] Y. Matsuzawa,et al. Thrombopoietin-induced differentiation of a human megakaryoblastic leukemia cell line, CMK, involves transcriptional activation of p21(WAF1/Cip1) by STAT5 , 1997, Molecular and cellular biology.
[95] A. Yoshimura,et al. CIS, a cytokine inducible SH2 protein, is a target of the JAK-STAT5 pathway and modulates STAT5 activation. , 1997, Blood.
[96] B. Druker,et al. Erythropoietin and interleukin-3 activate tyrosine phosphorylation of CBL and association with CRK adaptor proteins. , 1997, Blood.
[97] E. Nishida,et al. Activation of JNK signaling pathway by erythropoietin, thrombopoietin, and interleukin-3. , 1997, Blood.
[98] R. Salgia,et al. Thrombopoietin induces activation of the phosphatidylinositol‐3′ kinase pathway and formation of a complex containing p85PI3K and the protooncoprotein p120CBL , 1997, Journal of cellular physiology.
[99] S. Klinken,et al. Lyn tyrosine kinase is essential for erythropoietin‐induced differentiation of J2E erythroid cells , 1997, The EMBO journal.
[100] H. Lodish,et al. Identification of a novel pathway important for proliferation and differentiation of primary erythroid progenitors. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[101] R. Skoda,et al. The leptin receptor activates janus kinase 2 and signals for proliferation in a factor-dependent cell line. , 1997, Molecular endocrinology.
[102] A. Yoshimura,et al. STAT5 Activation Correlates with Erythropoietin Receptor-mediated Erythroid Differentiation of an Erythroleukemia Cell Line* , 1997, The Journal of Biological Chemistry.
[103] K. Kaushansky,et al. Dissecting the thrombopoietin receptor: functional elements of the Mpl cytoplasmic domain. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[104] L. Tartaglia,et al. The Leptin Receptor* , 1997, The Journal of Biological Chemistry.
[105] H. Lodish,et al. Functional interaction of erythropoietin and stem cell factor receptors is essential for erythroid colony formation. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[106] Y. Yamashita,et al. Tec protein-tyrosine kinase is involved in the thrombopoietin/c-Mpl signaling pathway. , 1997, Experimental hematology.
[107] T. Hirano,et al. An alternative pathway for STAT activation that is mediated by the direct interaction between JAK and STAT , 1997, Oncogene.
[108] N. Komatsu,et al. Protein kinase C and c-myc gene activation pathways in thrombopoietin signal transduction. , 1997, Biochemical and biophysical research communications.
[109] K. Xia,et al. Erythropoietin activates Raf1 by an Shc-independent pathway in CTLL-EPO-R cells. , 1997, Blood.
[110] N. Ben-Jonathan,et al. Extrapituitary prolactin: distribution, regulation, functions, and clinical aspects. , 1996, Endocrine reviews.
[111] W. Alexander,et al. Tyrosine‐599 of the c‐Mpl receptor is required for Shc phosphorylation and the induction of cellular differentiation. , 1996, The EMBO journal.
[112] P. Dentelli,et al. Discrete protein interactions with the Grb2/c-Cbl complex in SCF- and TPO-mediated myeloid cell proliferation. , 1996, Oncogene.
[113] M. Phillips,et al. Functional STAT 1 and 3 signaling by the leptin receptor (OB-R); reduced expression of the rat fatty leptin receptor in transfected cells. , 1996, Endocrinology.
[114] A. Sytkowski,et al. Protein kinase C-epsilon is necessary for erythropoietin's up-regulation of c-myc and for factor-dependent DNA synthesis. Evidence for discrete signals for growth and differentiation. , 1996, The Journal of biological chemistry.
[115] M. Gishizky,et al. Differentiation induced by the c-Mpl cytokine receptor is blocked by mutant Shc adaptor protein. , 1996, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[116] J. Darnell,et al. Leptin activation of Stat3 in the hypothalamus of wild–type and ob/ob mice but not db/db mice , 1996, Nature Genetics.
[117] B. Druker,et al. p120c-cbl is present in human blood platelets and is differentially involved in signaling by thrombopoietin and thrombin. , 1996, Blood.
[118] L. Tartaglia,et al. The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[119] F. Verdier,et al. Erythropoietin‐induced erythroid differentiation of the human erythroleukemia cell line TF‐1 correlates with impaired STAT5 activation. , 1996, The EMBO journal.
[120] T. He,et al. The box1 Domain of the Erythropoietin Receptor Specifies Janus Kinase 2 Activation and Functions Mitogenically within an Interleukin 2 β-Receptor Chimera* , 1996, The Journal of Biological Chemistry.
[121] R. Skoda,et al. Defective STAT signaling by the leptin receptor in diabetic mice. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[122] H. Broxmeyer,et al. Tyrosine 425 within the activated erythropoietin receptor binds Syp, reduces the erythropoietin required for Syp tyrosine phosphorylation, and promotes mitogenesis. , 1996, Blood.
[123] B. Groner,et al. Identification of tyrosine residues within the intracellular domain of the erythropoietin receptor crucial for STAT5 activation. , 1996, The EMBO journal.
[124] I. Dusanter-Fourt,et al. Functional regions of the mouse thrombopoietin receptor cytoplasmic domain: evidence for a critical region which is involved in differentiation and can be complemented by erythropoietin , 1996, Molecular and cellular biology.
[125] P. Majerus,et al. The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[126] J. Friedman,et al. Abnormal splicing of the leptin receptor in diabetic mice , 1996, Nature.
[127] L. Tartaglia,et al. Evidence That the Diabetes Gene Encodes the Leptin Receptor: Identification of a Mutation in the Leptin Receptor Gene in db/db Mice , 1996, Cell.
[128] V. D’Agati,et al. Differential effects of an erythropoietin receptor gene disruption on primitive and definitive erythropoiesis. , 1996, Genes & development.
[129] B. Druker,et al. Thrombopoietin induces tyrosine phosphorylation of Stat3 and Stat5 in human blood platelets. , 1996, Blood.
[130] Y. Yazaki,et al. Proto-oncogene products Vav and c-Cbl are involved in the signal transduction through Grb2/Ash in hematopoietic cells. , 1996, Acta haematologica.
[131] C. Marshall,et al. Control of the ERK MAP kinase cascade by Ras and Raf. , 1996, Cancer surveys.
[132] E. Melloni,et al. Correlation between levels of delta protein kinase C and resistance to differentiation in murine erythroleukemia cells. , 1996, Biochemical and biophysical research communications.
[133] Rene Devos,et al. Identification and expression cloning of a leptin receptor, OB-R , 1995, Cell.
[134] Y. Yazaki,et al. TPO/c-mpl ligand induces tyrosine phosphorylation of multiple cellular proteins including proto-oncogene products, Vav and c-Cbl, and Ras signaling molecules. , 1995, Biochemical and biophysical research communications.
[135] W. Alexander,et al. Point mutations within a dimer interface homology domain of c‐Mpl induce constitutive receptor activity and tumorigenicity. , 1995, The EMBO journal.
[136] J. Krosl,et al. Tyrosine 343 in the erythropoietin receptor positively regulates erythropoietin‐induced cell proliferation and Stat5 activation. , 1995, The EMBO journal.
[137] Thomas Madej,et al. Threading analysis suggests that the obese gene product may be a helical cytokine , 1995, FEBS letters.
[138] H. Lodish,et al. Interaction of the erythropoietin and stem-cell-factor receptors , 1995, Nature.
[139] H. Mano,et al. Interleukin 3 and erythropoietin induce association of Vav with Tec kinase through Tec homology domain. , 1995, Oncogene.
[140] R. Salgia,et al. The thrombopoietin receptor c-MPL activates JAK2 and TYK2 tyrosine kinases. , 1995, Experimental hematology.
[141] A. Gurney,et al. Distinct regions of c-Mpl cytoplasmic domain are coupled to the JAK-STAT signal transduction pathway and Shc phosphorylation. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[142] D. Levy,et al. Thrombopoietin activates a STAT5‐like factor in hematopoietic cells. , 1995, The EMBO journal.
[143] N. Copeland,et al. A novel cytokine‐inducible gene CIS encodes an SH2‐containing protein that binds to tyrosine‐phosphorylated interleukin 3 and erythropoietin receptors. , 1995, The EMBO journal.
[144] T. He,et al. Erythropoietin-induced recruitment of Shc via a receptor phosphotyrosine-independent, Jak2-associated pathway , 1995, The Journal of Biological Chemistry.
[145] J. Griffin,et al. The c-Mpl Ligand (Thrombopoietin) Stimulates Tyrosine Phosphorylation of Jak2, Shc, and c-Mpl (*) , 1995, The Journal of Biological Chemistry.
[146] H. Broxmeyer,et al. Involvement of SH2-containing Phosphotyrosine Phosphatase Syp in Erythropoietin Receptor Signal Transduction Pathways (*) , 1995, The Journal of Biological Chemistry.
[147] Ursula Klingmüller,et al. Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals , 1995, Cell.
[148] M. Maffei,et al. Positional cloning of the mouse obese gene and its human homologue , 1995, Nature.
[149] B. Druker,et al. Recombinant thrombopoietin induces rapid protein tyrosine phosphorylation of Janus kinase 2 and Shc in human blood platelets. , 1995, Blood.
[150] N. Aoki,et al. Activation of the mitogen-activated protein kinase pathway by the erythropoietin receptor. , 1994, The Journal of biological chemistry.
[151] K. Siminovitch,et al. Identification of PTP1C mutation as the genetic defect in motheaten and viable motheaten mice: a step toward defining the roles of protein tyrosine phosphatases in the regulation of hemopoietic cell differentiation and function. , 1994, Clinical immunology and immunopathology.
[152] L. Yu-Lee,et al. Transcriptional regulation by the helix bundle peptide hormones: growth hormone, prolactin, and hematopoietic cytokines. , 1994, Endocrine reviews.
[153] G. Krystal,et al. Multiple cytokines stimulate the binding of a common 145-kilodalton protein to Shc at the Grb2 recognition site of Shc , 1994, Molecular and cellular biology.
[154] N. Komatsu,et al. Erythropoietin induces tyrosine phosphorylation and activation of phospholipase C-gamma 1 in a human erythropoietin-dependent cell line. , 1994, The Journal of biological chemistry.
[155] H. Lodish,et al. Activation and inhibition of erythropoietin receptor function: role of receptor dimerization , 1994, Molecular and cellular biology.
[156] E. Melloni,et al. Protein kinase C isoforms in murine erythroleukemia cells and their involvement in the differentiation process , 1994, FEBS letters.
[157] N. Aoki,et al. Erythropoietin-dependent association of phosphatidylinositol 3-kinase with tyrosine-phosphorylated erythropoietin receptor. , 1994, The Journal of biological chemistry.
[158] O. Silvennoinen,et al. JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin , 1993, Cell.
[159] P. Leder,et al. Murine c‐mpl: a member of the hematopoietic growth factor receptor superfamily that transduces a proliferative signal. , 1993, The EMBO journal.
[160] Y. Yazaki,et al. Erythropoietin induces tyrosine phosphorylation and kinase activity of the c-fps/fes proto-oncogene product in human erythropoietin-responsive cells. , 1993, Blood.
[161] J. Cleveland,et al. Inactivation of erythropoietin receptor function by point mutations in a region having homology with other cytokine receptors , 1993, Molecular and cellular biology.
[162] J. Mornon,et al. Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: identification of a member of the hematopoietic growth factor receptor superfamily. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[163] N. Casadevall,et al. Erythropoietin induces the tyrosine phosphorylation of its own receptor in human erythropoietin-responsive cells. , 1992, The Journal of biological chemistry.
[164] H. Lodish,et al. Homodimerization and constitutive activation of the erythropoietin receptor. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[165] J. Ihle,et al. Induction of tyrosine phosphorylation by the erythropoietin receptor correlates with mitogenesis , 1991, Molecular and cellular biology.
[166] F. Wendling,et al. A putative truncated cytokine receptor gene transduced by the myeloproliferative leukemia virus immortalizes hematopoietic progenitors , 1990, Cell.
[167] A. D’Andrea,et al. Human erythropoietin receptor: cloning, expression, and biologic characterization. , 1990, Blood.
[168] H. Lodish,et al. Expression cloning of the murine erythropoietin receptor , 1989, Cell.
[169] K P Hummel,et al. Diabetes, a New Mutafton in the Mouse , 1966, Science.
[170] M. Dickie,et al. Obese, a new mutation in the house mouse. , 1950, The Journal of heredity.