Role of poly(ADP-ribose) polymerase-1 in regulating human islet cell differentiation

[1]  W. Kraus,et al.  The expanding universe of PARP1-mediated molecular and therapeutic mechanisms. , 2022, Molecular cell.

[2]  N. Dadheech,et al.  Direct lineage tracing reveals Activin-a potential for improved pancreatic homing of bone marrow mesenchymal stem cells and efficient ß-cell regeneration in vivo , 2020, Stem Cell Research & Therapy.

[3]  Olga I Lavrik,et al.  Poly(ADP-ribosyl)ation by PARP1: reaction mechanism and regulatory proteins , 2019, Nucleic acids research.

[4]  N. Dadheech,et al.  Pancreatic resident endocrine progenitors demonstrate high islet neogenic fidelity and committed homing towards diabetic mice pancreas , 2018, Journal of cellular physiology.

[5]  S. Snyder,et al.  Opportunities for the repurposing of PARP inhibitors for the therapy of non‐oncological diseases , 2018, British journal of pharmacology.

[6]  A. Naura,et al.  Poly(ADP-Ribose)Polymerase-1 in Lung Inflammatory Disorders: A Review , 2017, Front. Immunol..

[7]  Arnab Ray Chaudhuri,et al.  The multifaceted roles of PARP1 in DNA repair and chromatin remodelling , 2017, Nature Reviews Molecular Cell Biology.

[8]  S. Stamm,et al.  Involvement of PARP1 in the regulation of alternative splicing , 2016, Cell Discovery.

[9]  N. Paranjape,et al.  Swertisin an Anti-Diabetic Compound Facilitate Islet Neogenesis from Pancreatic Stem/Progenitor Cells via p-38 MAP Kinase-SMAD Pathway: An In-Vitro and In-Vivo Study , 2015, PloS one.

[10]  Sejal Vyas,et al.  New PARP targets for cancer therapy , 2014, Nature Reviews Cancer.

[11]  G. Ghirlanda,et al.  Oxidative Stress in Diabetes: Implications for Vascular and Other Complications , 2013, International journal of molecular sciences.

[12]  Lei Gong,et al.  Poly (ADP-Ribose) Transferase/Polymerase-1-Deficient Mice Resistant to Age-Dependent Decrease in β-Cell Proliferation , 2012, Molecular medicine.

[13]  N. Garg,et al.  Signaling mechanism of poly(ADP-ribose) polymerase-1 (PARP-1) in inflammatory diseases. , 2011, The American journal of pathology.

[14]  A. Tulin,et al.  The roles of PARP1 in gene control and cell differentiation. , 2010, Current opinion in genetics & development.

[15]  W. Kraus,et al.  The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets. , 2010, Molecular cell.

[16]  S. Kaufmann,et al.  PARP inhibition: PARP1 and beyond , 2010, Nature Reviews Cancer.

[17]  V. Nicoletti,et al.  Parp and Cell Death or Protection in Rat Primary Astroglial Cell Cultures Under LPS/IFNγ Induced Proinflammatory Conditions , 2008, Neurochemical Research.

[18]  Hiroshi Suzuki,et al.  Loss of Parp-1 affects gene expression profile in a genome-wide manner in ES cells and liver cells , 2007, BMC Genomics.

[19]  J. Yélamos,et al.  PARP‐2 deficiency affects the survival of CD4+CD8+ double‐positive thymocytes , 2006, The EMBO journal.

[20]  V. Schreiber,et al.  Poly(ADP-ribose): novel functions for an old molecule , 2006, Nature Reviews Molecular Cell Biology.

[21]  L. Olson,et al.  MafA expression and insulin promoter activity are induced by nicotinamide and related compounds in INS-1 pancreatic beta-cells. , 2006, Diabetes.

[22]  Michael Brownlee,et al.  The pathobiology of diabetic complications: a unifying mechanism. , 2005, Diabetes.

[23]  Csaba Szabó,et al.  Poly(ADP-Ribose) Polymerase Is Involved in the Development of Diabetic Retinopathy via Regulation of Nuclear Factor-κB , 2004 .

[24]  Fei Li,et al.  Role of poly(ADP-ribose) polymerase activation in diabetic neuropathy. , 2004, Diabetes.

[25]  O. Madsen,et al.  Nestin Is Expressed in Vascular Endothelial Cells in the Adult Human Pancreas , 2003, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[26]  B. Raaka,et al.  Human pancreatic precursor cells secrete FGF2 to stimulate clustering into hormone-expressing islet-like cell aggregates , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[27]  S. Takasawa,et al.  Activation of Reg gene, a gene for insulin-producing beta -cell regeneration: poly(ADP-ribose) polymerase binds Reg promoter and regulates the transcription by autopoly(ADP-ribosyl)ation. , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[28]  S. Snyder,et al.  Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[29]  H. Kolb,et al.  Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin , 1999, Nature Medicine.

[30]  Y. L. Rhun,et al.  Cellular responses to DNA damage in the absence of Poly(ADP-ribose) polymerase. , 1998, Biochemical and biophysical research communications.

[31]  E. Wagner,et al.  Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease. , 1995, Genes & development.

[32]  H. Okamoto,et al.  Amelioration of Diabetes Mellitus in Partially Depancreatized Rats by Poly(ADP-ribose) Synthetase Inhibitors: Evidence of Islet B-Cell Regeneration , 1984, Diabetes.

[33]  H. Okamoto,et al.  Streptozotocin and alloxan induce DNA strand breaks and poly(ADP–ribose) synthetase in pancreatic islets , 1981, Nature.

[34]  K. Murthy,et al.  Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation , 2001, Nature Medicine.