South Asian Patients With Ischemic Stroke: Intracranial Large Arteries Are the Predominant Site of Disease

Background and Purpose— South Asians are the most prevalent ethnic group in the world. Intracranial disease is the most common vascular lesion worldwide. Methods— We prospectively studied 200 consecutive ethnic South Asian patients with acute ischemic stroke in Singapore. Results— Intracranial large-artery disease was prevalent among 54% of all stroke subtypes and was independently associated with hypertension and higher serum erythrocyte sedimentation rate. Conclusions— Among ethnic South Asian patients with ischemic stroke, intracranial large arteries are the predominant site of disease.

[1]  N. Papamitsakis,et al.  Cerebrovascular disease among patients from the Indian subcontinent , 2006, Neurology.

[2]  L. Wong.  Global Burden of Intracranial Atherosclerosis , 2006, International journal of stroke : official journal of the International Stroke Society.

[3]  E. Mori,et al.  Risk factors for occlusive lesions of intracranial arteries in stroke‐free Japanese , 2005, European journal of neurology.

[4]  J. Reddy,et al.  Subtypes of ischemic stroke in a metropolitan city of South India (one year data from a hospital based stroke registry) , 2002 .

[5]  A. Hofman,et al.  C-Reactive Protein Predicts Progression of Atherosclerosis Measured at Various Sites in the Arterial Tree: The Rotterdam Study , 2002, Stroke.

[6]  A. Ahuja,et al.  Use of Transcranial Doppler Ultrasound to Predict Outcome in Patients With Intracranial Large-Artery Occlusive Disease , 2000, Stroke.

[7]  M. Takahashi,et al.  Intracranial vascular stenosis and occlusion: diagnostic accuracy of three-dimensional, Fourier transform, time-of-flight MR angiography. , 1994, Radiology.

[8]  H. Adams,et al.  Interphysician agreement in the diagnosis of subtypes of acute ischemic stroke , 1993, Neurology.

[9]  David Lee Gordon,et al.  Classification of Subtype of Acute Ischemic Stroke: Definitions for Use in a Multicenter Clinical Trial , 1993, Stroke.

[10]  C. Weiller,et al.  Type and extent of hemispheric brain infarctions and clinical outcome in early and delayed middle cerebral artery recanalization , 1992, Neurology.