Colonic perforation after rituximab treatment for posttransplant lymphoproliferative disorder.
暂无分享，去创建一个
FIGURE 4. Gross pathology specimen showing a 1.5-cm defect in the sigmoid colonic wall. FIGURE 3. Colonoscopy performed postrituximab therapy. Large perforation noted in the sigmoid colon. FIGURE 2. Histology of colonic biopsy shows nuclear positivity for Epstein-Barr virus–encoded RNA (EBER) by in situ hybridization (black arrows) (EBER in situ hybridization; original magnification 200). FIGURE 1. Magnetic resonance enterography of the abdomen showing retroperitoneal lymphadenopathy, evidence of mesenteric infiltration, focal dilatation, and bowel wall thickening in the sigmoid colon (yellow arrow) suggestive of posttransplant lymphoproliferative disorder.
[1] Mary Bohnenblust,et al. Intestinal perforation associated with rituximab therapy for post-transplant lymphoproliferative disorder after liver transplantation , 2009, Cancer Chemotherapy and Pharmacology.
[2] C. Maurer,et al. Intestinal lymphoma perforations as a consequence of highly effective anti-CD20 antibody therapy. , 2002, Transplantation.
[3] G. Dodd,et al. Thoracic and abdominal manifestations of lymphoma occurring in the immunocompromised patient. , 1992, Radiologic clinics of North America.