Recombinant human C1‐inhibitor in the treatment of acute angioedema attacks

BACKGROUND: Patients with hereditary C1‐inhibitor deficiency have recurrent attacks of angioedema, preferably treated with C1‐inhibitor concentrate. A recombinant human C1‐inhibitor (rHuC1INH) was developed, derived from milk from transgenic rabbits. This study was undertaken to investigate the effects of rHuC1INH in the treatment of acute angioedema attacks in patients with a hereditary C1‐inhibitor deficiency.

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