Clusters of activated microglia in normal-appearing white matter show signs of innate immune activation
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J. Geurts | H. D. de Vries | S. Amor | P. J. van den Elsen | P. Van Der Valk | Evert-jan Kooi | S. V. D. van der Pol | J. van Horssen | M. Kipp | L. Peferoen | R. Peferoen-Baert | W. Gerritsen | Shailender Singh | M. Witte | Jamie L. Lim | Susanne M. A. van der Pol | R. Peferoen‐Baert | Evert-Jan Kooi
[1] H. Lassmann,et al. Explorer NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury , 2012 .
[2] H. Lassmann,et al. The molecular basis of neurodegeneration in multiple sclerosis , 2011, FEBS letters.
[3] X. Montalban,et al. Tumor necrosis factor alpha (TNF-α), anti-TNF-α and demyelination revisited: An ongoing story , 2011, Journal of Neuroimmunology.
[4] H. D. de Vries,et al. Radical changes in multiple sclerosis pathogenesis. , 2011, Biochimica et biophysica acta.
[5] J. Geurts,et al. Preactive multiple sclerosis lesions offer novel clues for neuroprotective therapeutic strategies. , 2011, CNS & neurological disorders drug targets.
[6] Helga E de Vries,et al. Mitochondrial dysfunction: a potential link between neuroinflammation and neurodegeneration? , 2010, Mitochondrion.
[7] Daniela Prayer,et al. Reduced NAA-Levels in the NAWM of Patients with MS Is a Feature of Progression. A Study with Quantitative Magnetic Resonance Spectroscopy at 3 Tesla , 2010, PloS one.
[8] L. Steinman,et al. &agr;B-Crystallin Is a Target for Adaptive Immune Responses and a Trigger of Innate Responses in Preactive Multiple Sclerosis Lesions , 2010, Journal of neuropathology and experimental neurology.
[9] P. Stys,et al. Mechanisms of axonal injury: internodal nanocomplexes and calcium deregulation. , 2010, Trends in molecular medicine.
[10] D. Baker,et al. Inflammation in neurodegenerative diseases , 2010, Immunology.
[11] S. Nataf. Neuroinflammation responses and neurodegeneration in multiple sclerosis. , 2009, Revue neurologique.
[12] J. Geurts,et al. Enhanced number and activity of mitochondria in multiple sclerosis lesions , 2009, The Journal of pathology.
[13] W. Brück,et al. Molecular Changes in White Matter Adjacent to an Active Demyelinating Lesion in Early Multiple Sclerosis , 2009, Brain pathology.
[14] S. Amor,et al. Preactive lesions in multiple sclerosis , 2009, Current opinion in neurology.
[15] R. Gold,et al. Function of neurotrophic factors beyond the nervous system: inflammation and autoimmune demyelination. , 2009, Critical reviews in immunology.
[16] P. Calabresi,et al. A defect of sphingolipid metabolism modifies the properties of normal appearing white matter in multiple sclerosis , 2008, Brain : a journal of neurology.
[17] B. Trapp,et al. Multiple sclerosis: an immune or neurodegenerative disorder? , 2008, Annual review of neuroscience.
[18] Hans Lassmann,et al. Mitochondrial defects in acute multiple sclerosis lesions , 2008, Brain : a journal of neurology.
[19] R. Reynolds,et al. Normal-appearing white matter in multiple sclerosis is in a subtle balance between inflammation and neuroprotection. , 2007, Brain : a journal of neurology.
[20] H. Lassmann,et al. Lesion genesis in a subset of patients with multiple sclerosis: a role for innate immunity? , 2007, Brain : a journal of neurology.
[21] Hans Lassmann,et al. Remyelination is extensive in a subset of multiple sclerosis patients. , 2006, Brain : a journal of neurology.
[22] L. Bö,et al. NAD(P)H:quinone oxidoreductase 1 expression in multiple sclerosis lesions. , 2006, Free radical biology & medicine.
[23] L. Rasmussen,et al. Targeting of O6-MeG DNA methyltransferase (MGMT) to mitochondria protects against alkylation induced cell death. , 2005, Mitochondrion.
[24] C. Teunissen,et al. Macrophages and neurodegeneration , 2005, Brain Research Reviews.
[25] M. Barnett,et al. Relapsing and remitting multiple sclerosis: Pathology of the newly forming lesion , 2004, Annals of neurology.
[26] R. Reynolds,et al. Molecular Changes in Normal Appearing White Matter in Multiple Sclerosis are Characteristic of Neuroprotective Mechanisms Against Hypoxic Insult , 2003, Brain pathology.
[27] B. Trapp,et al. Subpial Demyelination in the Cerebral Cortex of Multiple Sclerosis Patients , 2003, Journal of neuropathology and experimental neurology.
[28] R. Kinkel,et al. Axonal loss in normal-appearing white matter in a patient with acute MS , 2001, Neurology.
[29] F Barkhof,et al. Post-mortem MRI-guided sampling of multiple sclerosis brain lesions: increased yield of active demyelinating and (p)reactive lesions. , 2001, Brain : a journal of neurology.
[30] I. V. Allen,et al. Pathological abnormalities in the normal-appearing white matter in multiple sclerosis , 2001, Neurological Sciences.
[31] C. D. DE GROOT,et al. Staging of multiple sclerosis (MS) lesions: pathology of the time frame of MS , 2000, Neuropathology and applied neurobiology.
[32] M. Esiri,et al. The application of multifactorial cluster analysis in the staging of plaques in early multiple sclerosis. Identification and characterization of the primary demyelinating lesion. , 1997, Brain : a journal of neurology.
[33] H. Lassmann,et al. Histopathology and the blood–cerebrospinal fluid barrier in multiple sclerosis , 1994, Annals of neurology.
[34] A. Verhoeven,et al. Characterization of two monoclonal antibodies against cytochrome b558 of human neutrophils. , 1989, Blood.
[35] M. Duchowny,et al. Cytomegalovirus infection of the adult nervous system , 1979, Annals of neurology.