论文信息 - Pulmonary large cell neuroendocrine carcinoma with adrenal oligorecurrence successfully treated by adrenalectomy

Pulmonary large cell neuroendocrine carcinoma with adrenal oligorecurrence successfully treated by adrenalectomy

A 63‐year‐old man suspected of having lung cancer underwent right upper lobectomy and was diagnosed with large cell neuroendocrine carcinoma (LCNEC). Eleven months after surgery, he developed an oligorecurrence in the adrenal gland and underwent left adrenalectomy. The specimen revealed LCNEC metastasis. Forty‐one months after surgery, enlargement of a lesion near the surgical site was seen. Biopsy showed LCNEC metastasis and he is currently undergoing radiotherapy for the recurrent lesion. We report a case of LCNEC with adrenal gland oligorecurrence treated by adrenalectomy, which led to long‐term survival.

[1] J. Lee,et al. Local Consolidative Therapy Vs. Maintenance Therapy or Observation for Patients With Oligometastatic Non-Small-Cell Lung Cancer: Long-Term Results of a Multi-Institutional, Phase II, Randomized Study. , 2019, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[2] H. Groen,et al. Clinical features of large cell neuroendocrine carcinoma: a population-based overview , 2015, European Respiratory Journal.

[3] J. Wain,et al. Outcomes of patients with isolated adrenal metastasis from non-small cell lung carcinoma. , 2011, The Annals of thoracic surgery.

[4] G. Pelosi,et al. Large cell neuroendocrine carcinoma of the lung: a retrospective analysis of 144 surgical cases. , 2006, Lung cancer.

[5] T. Kuga,et al. [Metastatic carcinoma of the adrenal gland from large cell neuroendocrine carcinoma; report of a case]. , 2005, Kyobu geka. The Japanese journal of thoracic surgery.