The effect of the red cell membrane and a diffusion boundary layer on the rate of oxygen uptake by human erythrocytes

1. This paper deals with the contributions of the red cell membrane and an external diffusion boundary layer (‘unstirred layer’) to the resistance to O2 entry into the red cell. Bovine serum albumin (BSA) was added to the extracellular fluid to enhance the effect of the diffusion boundary layer by diminishing both the solubility and the diffusivity of O2. The rate of O2 uptake by human red cells at various extracellular BSA concentrations was determined with a stopped‐flow rapid‐reaction apparatus.

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