PERSONAL PRACTICE Preoperative and postoperative pain control

Interest in pain management for children in the perioperative period has increased substantially in the past few years and this has led to very significant changes in this area of clinical practice. The quality of pain control that can be achieved is more often a function of the time and resources devoted to it, rather than the actual regimens employed. A well coordinated multidisciplinary approach will achieve the best results and 'acute pain control teams' are being established in many hospitals with this aim. Acute pain treatment in children is subject to special problems because they are such a diverse population. The response to analgesics varies with age and side effects are often unpredictable. Pain is difficult to assess in preverbal children which further complicates its management. Fortunately there have been a number of advances recently that have allowed improvements in pain management. The mechanisms of pain transmission are more completely understood, the pharmacokinetics and pharmacodynamics of analgesic drugs in small children have been described, and new techniques of pain control have come into practice.

[1]  D. Murphy NSAIDs and postoperative pain. , 1993, BMJ.

[2]  D. Murphy,et al.  Preoperative indomethacin for pain relief after thoracotomy: comparison with postoperative indomethacin. , 1993, British journal of anaesthesia.

[3]  H. Kokki,et al.  Comparison of intravenous ketorolac with morphine for postoperative pain in children , 1992, Clinical pharmacology and therapeutics.

[4]  J. Slattery,et al.  The maturation of morphine clearance and metabolism. , 1992, American journal of diseases of children.

[5]  B. Brandom,et al.  Changes in drug requirements during growth , 1992 .

[6]  T. Vetter Pediatric patient-controlled analgesia with morphine versus meperidine. , 1992, Journal of pain and symptom management.

[7]  R. Bhat,et al.  Morphine metabolism in acutely ill preterm newborn infants. , 1992, The Journal of pediatrics.

[8]  T. Mogensen,et al.  A comparison between preincisional and postincisional lidocaine infiltration and postoperative pain. , 1992, Anesthesia and analgesia.

[9]  M. Kilian,et al.  Does opiate premedication influence postoperative analgesia? A prospective study , 1992, Pain.

[10]  K. Anand,et al.  Halothane-morphine compared with high-dose sufentanil for anesthesia and postoperative analgesia in neonatal cardiac surgery. , 1992, The New England journal of medicine.

[11]  B. Dalens,et al.  Intervertebral epidural anaesthesia in paediatric surgery: success rate and adverse effects in 650 consecutive procedures , 1991 .

[12]  P. McGrath,et al.  Discordance between self-report and behavioral pain measures in children aged 3-7 years after surgery. , 1990, Journal of pain and symptom management.

[13]  J. Beyer,et al.  The assessment of pain in children. , 1989, Pediatric clinics of North America.

[14]  C. Woolf,et al.  Recent advances in the pathophysiology of acute pain. , 1989, British journal of anaesthesia.

[15]  V. Walt,et al.  Patient-Controlled Analgesia in Children , 1989, Anaesthesia and intensive care.

[16]  R. Meyer,et al.  Peripheral Mechanisms of Somatic Pain , 1988, Anesthesiology.

[17]  K. Anand,et al.  Pain and its effects in the human neonate and fetus. , 1987, The New England journal of medicine.

[18]  C. McArdle,et al.  The morphine sparing effect of ketorolac tromethamine , 1987, Anaesthesia.

[19]  J. Slattery,et al.  Morphine Pharmacokinetics in Early Infancy , 1987, Anesthesiology.

[20]  R. Glavin,et al.  Ibuprofen in the management of postoperative pain. , 1986, British journal of anaesthesia.

[21]  J. Haberer,et al.  Lumbar epidural anesthesia for operative and postoperative pain relief in infants and young children. , 1986, Anesthesia and analgesia.

[22]  L. Mcnicol,et al.  Local anaesthetic techniques in paediatric surgery. , 1986, British journal of anaesthesia.

[23]  K. Samii,et al.  Lumbar and thoracic epidural anesthesia for urologic and upper abdominal surgery in infants and children. , 1986, Anesthesiology.

[24]  M. E. Owens Pain in infancy: Conceptual and methodological issues , 1984, Pain.

[25]  D. E. Koehntop,et al.  Pharmacokinetics of Fentanyl in Neonates , 1984, Anesthesia and analgesia.

[26]  M. Warner,et al.  Postoperative use of epidurally administered morphine in children and adolescents. , 1984, Mayo Clinic proceedings.

[27]  S. Jones,et al.  Intrathecal morphine for postoperative pain relief in children. , 1984, British journal of anaesthesia.

[28]  D. Steward,et al.  Regional analgesia for postoperative pain in pediatric outpatient surgery. , 1980, Journal of pediatric surgery.

[29]  G. Chojnacka-Szawłowska,et al.  [Psychological and psychiatric aspects of pain]. , 1979, Psychiatria polska.

[30]  D. Dalrymple,et al.  Factors predisposing to postoperative pain and pulmonary complications. A study of male patients undergoing elective gastric surgery. , 1974, British journal of anaesthesia.

[31]  P. McGrath,et al.  The Clinical Measurement of Pain in Children: A Review , 1985 .

[32]  R. Melzack The gate control theory of pain. , 1978, British medical journal.