Catalytic and highly efficient 1,4-addition of terminal alkynes to conjugated enones by [RuCl(2)(p-cymene)]2/pyrrolidine.

[reaction: see text] A wide range of terminal alkynes was added to conjugated enones in a 1,4-fashion by a ruthenium catalyst in the presence of catalytic amounts of an amine base, and the corresponding gamma,delta-alkynyl ketones were obtained in good to excellent yields.

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