Prevalence of bipolar spectrum disorder in Korean college students according to the K-MDQ

Background The purpose of this study was to assess the prevalence of bipolar spectrum disorder (BSD) in the general Korean population. Methods A sample of college students (n = 1026) was stratified to reflect geographical differences accurately in Korean college students. The Korean version of the Mood Disorder Questionnaire (K-MDQ) was administered and an epidemiological survey carried out between November 2006 and February 2007. BSD was defined as a score of at least seven K-MDQ symptoms that co-occurred and resulted in minimal or more functional impairment. Results The prevalence of BSD was 18.6% (95% confidence interval [CI] 16.2–21.0) in total, being 19.8% (95% CI 16.3–23.2) in men and 17.5% (95% CI 14.2–20.8) in women. The prevalence of BSD was more common in rural dwellers than in urban dwellers (P = 0.008, chi-square test). Univariate and multivariate regression models showed that rural residence was a significant factor associated with BSD. There were significant relationships between BSD and gender, age, and socioeconomic status. Conclusion The prevalence of BSD found in the present study is higher than that reported by other epidemiological studies in Korea and in international studies.

[1]  H. Lee,et al.  The Epidemiology of Alcohol Use Disorders , 2012 .

[2]  M. Zimmerman,et al.  Screening for Bipolar Disorder with the Mood Disorders Questionnaire: A Review , 2011, Harvard review of psychiatry.

[3]  K. Merikangas,et al.  Prevalence and correlates of bipolar spectrum disorder in the world mental health survey initiative. , 2011, Archives of general psychiatry.

[4]  D. Dawson,et al.  The prevalence and correlates of alcohol use disorders in the United States and Korea--a cross-national comparative study. , 2010, Alcohol.

[5]  K. Chung,et al.  Validation of the Mood Disorder Questionnaire in the general population in Hong Kong. , 2009, Comprehensive psychiatry.

[6]  R. Kessler,et al.  Bipolar Disorder with frequent mood episodes in the National Comorbidity Survey Replication (NCS-R) , 2009, Molecular Psychiatry.

[7]  M. Berk,et al.  Reliability of the Mood Disorder Questionnaire: Comparison with the Structured Clinical Interview for the DSM-IV-TR in a Population Sample , 2009, The Australian and New Zealand journal of psychiatry.

[8]  Kyooseob Ha,et al.  Validity and reliability of the Korean version of the Mood Disorder Questionnaire. , 2009, Comprehensive psychiatry.

[9]  H. Jeon,et al.  Prevalence and Correlates of Major Mental Disorders among Korean Adults:A 2006 National Epidemiologic Survey , 2009 .

[10]  Steven H. Jones,et al.  Validation of the Mood Disorder Questionnaire for screening for bipolar disorder in a UK sample. , 2008, Journal of affective disorders.

[11]  M. Wong,et al.  Validation of the Chinese version of the Mood Disorder Questionnaire in a psychiatric population in Hong Kong , 2008, Psychiatry and clinical neurosciences.

[12]  M. Nordentoft,et al.  A comparison of selected risk factors for unipolar depressive disorder, bipolar affective disorder, schizoaffective disorder, and schizophrenia from a danish population-based cohort. , 2007, The Journal of clinical psychiatry.

[13]  D. Charney,et al.  Diagnosing bipolar disorder in trauma exposed primary care patients. , 2007, Bipolar disorders.

[14]  R. Kessler,et al.  Lifetime and 12-month prevalence of bipolar spectrum disorder in the National Comorbidity Survey replication. , 2007, Archives of general psychiatry.

[15]  J. Os,et al.  Evidence that the urban environment specifically impacts on the psychotic but not the affective dimension of bipolar disorder , 2006, Social Psychiatry and Psychiatric Epidemiology.

[16]  P. Mortensen,et al.  Urbanicity during upbringing and bipolar affective disorders in Denmark. , 2006, Bipolar disorders.

[17]  G. Fava,et al.  Assessing the Community Prevalence of Bipolar Spectrum Symptoms by the Mood Disorder Questionnaire , 2005, Psychotherapy and Psychosomatics.

[18]  S. Ghaemi,et al.  Sensitivity and specificity of the Mood Disorder Questionnaire for detecting bipolar disorder. , 2004, Journal of affective disorders.

[19]  M. Cho,et al.  Korean Epidemiologic Catchment Area(KECA) Study for Psychiatric Disorderscc: Prevalence of Specific Psychiatric Disorders , 2004 .

[20]  L. Arnold,et al.  Gender differences in bipolar disorder. , 2003, The Psychiatric clinics of North America.

[21]  J. Calabrese,et al.  Impact of bipolar disorder on a U.S. community sample. , 2003, The Journal of clinical psychiatry.

[22]  John A. Rice,et al.  The long-term natural history of the weekly symptomatic status of bipolar I disorder. , 2002, Archives of general psychiatry.

[23]  W. Nolen,et al.  Bipolar disorder in the general population in The Netherlands (prevalence, consequences and care utilisation): results from The Netherlands Mental Health Survey and Incidence Study (NEMESIS). , 2002, Journal of affective disorders.

[24]  J. Calabrese,et al.  Development and validation of a screening instrument for bipolar spectrum disorder: the Mood Disorder Questionnaire. , 2000, The American journal of psychiatry.

[25]  G. Devins,et al.  Quality of life and lifestyle disruption in euthymic bipolar disorder. , 1997, Journal of psychiatric research.

[26]  C. Hammen,et al.  Relapse and impairment in bipolar disorder. , 1995, The American journal of psychiatry.

[27]  Y. H. Lee,et al.  The nationwide epidemiological study of mental disorders in korea. , 1987, Journal of Korean medical science.

[28]  J. Seok,et al.  Screening of Bipolar Disorders in High School Students , 2009 .

[29]  G. Hawthorne,et al.  Bipolar I and II disorders in a random and representative Australian population. , 2005, The Australian and New Zealand journal of psychiatry.

[30]  Mark A Frye,et al.  Screening for bipolar disorder in the community. , 2003, The Journal of clinical psychiatry.

[31]  L. Judd,et al.  The prevalence and disability of bipolar spectrum disorders in the US population: re-analysis of the ECA database taking into account subthreshold cases. , 2003, Journal of affective disorders.

[32]  H. Akiskal,et al.  The dual factor structure of self-rated MDQ hypomania: energized-activity versus irritable-thought racing. , 2003, Journal of affective disorders.

[33]  A. Marneros,et al.  TEMPS-a scale in 'mixed' and 'pure' manic episodes: new data and methodological considerations on the relevance of joint anxious-depressive temperament traits. , 2003, Journal of affective disorders.

[34]  H. Akiskal,et al.  The role of cyclothymia in atypical depression: toward a data-based reconceptualization of the borderline-bipolar II connection. , 2003, Journal of affective disorders.

[35]  M. First,et al.  Structured Clinical Interview for DSM-IV Axis I Disorders , 1997 .

[36]  P. Bebbington The epidemiology of affective disorders. , 1991 .

[37]  R. Hirschfeld,et al.  Epidemiology of affective disorders. , 1982, Archives of general psychiatry.