Acetyl-CoA carboxylase (ACC) inhibitor GS-0976 leads to suppression of hepatic de novo lipogenesis and significant improvements in MRI-PDFF, MRE, and markers of fibrosis after 12 weeks of therapy in patients with NASH
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C. Sirlin | M. Hellerstein | M. Middleton | Edna Nyangau | J. McHutchison | E. Lawitz | R. Myers | Kelvin W. Li | F. Poordad | G. Subramanian | N. Loo | A. Coste | B. McColgan | M. Fitch | C. Jia | C. Djedjos | R. Xu