Mammalian lipoxygenases and their biological relevance.

[1]  S. Stohs,et al.  What You Should Know About Omega-3 Fatty Acids and Prostate Cancer , 2014, Journal of dietary supplements.

[2]  A. Xu,et al.  Ancestral genetic complexity of arachidonic acid metabolism in Metazoa. , 2014, Biochimica et biophysica acta.

[3]  H. Forman,et al.  An overview of mechanisms of redox signaling. , 2014, Journal of molecular and cellular cardiology.

[4]  S. Doré,et al.  Neurovascular protection by post‐ischemic intravenous injections of the lipoxin A4 receptor agonist, BML‐111, in a rat model of ischemic stroke , 2014, Journal of neurochemistry.

[5]  M. Hersberger,et al.  Association of polymorphisms in the ALOX15B gene with coronary artery disease. , 2014, Clinical biochemistry.

[6]  Adam Yasgar,et al.  Potent and Selective Inhibitors of Human Reticulocyte 12/15-Lipoxygenase as Anti-Stroke Therapies , 2014, Journal of medicinal chemistry.

[7]  A. Montpetit,et al.  ALOX12 in Human Toxoplasmosis , 2014, Infection and Immunity.

[8]  J. Yu,et al.  Increased metabolites of 5-lipoxygenase from hypoxic ovarian cancer cells promote tumor-associated macrophage infiltration , 2014, Oncogene.

[9]  P. Krieg,et al.  The role of lipoxygenases in epidermis. , 2014, Biochimica et biophysica acta.

[10]  Christopher P. Thomas,et al.  The importance of the lipoxygenase-hepoxilin pathway in the mammalian epidermal barrier. , 2014, Biochimica et biophysica acta.

[11]  J. Cho,et al.  Genetic ablation and short-duration inhibition of lipoxygenase results in increased macroautophagy. , 2014, Experimental cell research.

[12]  N. Yapar.  Epidemiology and risk factors for invasive candidiasis , 2014, Therapeutics and clinical risk management.

[13]  G. Bergström,et al.  Arachidonate 15-Lipoxygenase Enzyme Products Increase Platelet Aggregation and Thrombin Generation , 2014, PloS one.

[14]  M. Newcomer,et al.  The Structure of Human 15-Lipoxygenase-2 with a Substrate Mimic* , 2014, The Journal of Biological Chemistry.

[15]  Yuan Zhang,et al.  Cysteinyl leukotrienes and their receptors: bridging inflammation and colorectal cancer. , 2014, World journal of gastroenterology.

[16]  F. Ducharme,et al.  Addition to inhaled corticosteroids of long-acting beta2-agonists versus anti-leukotrienes for chronic asthma. , 2014, The Cochrane database of systematic reviews.

[17]  S. Kohno,et al.  Leukotriene receptor antagonists pranlukast and montelukast for treating asthma , 2014, Expert opinion on pharmacotherapy.

[18]  Rong Liu,et al.  The arachidonate 5-lipoxygenase-activating protein (ALOX5AP) gene SG13S114 polymorphism and ischemic stroke in Chinese population: a meta-analysis. , 2014, Gene.

[19]  C. Serhan,et al.  Resolvins, specialized proresolving lipid mediators, and their potential roles in metabolic diseases. , 2014, Cell metabolism.

[20]  M. Holinstat,et al.  The emerging role of oxylipins in thrombosis and diabetes , 2014, Front. Pharmacol..

[21]  C. Karp,et al.  Role of the Lipoxygenase Pathway in RSV-induced Alternatively Activated Macrophages Leading to Resolution of Lung Pathology , 2013, Mucosal Immunology.

[22]  W. Lukiw,et al.  Regulation of Neurotropic Signaling by the Inducible, NF-kB-Sensitive miRNA-125b in Alzheimer's Disease (AD) and in Primary Human Neuronal-Glial (HNG) Cells , 2013, Molecular Neurobiology.

[23]  L. Eckhart,et al.  Cell death by cornification. , 2013, Biochimica et biophysica acta.

[24]  C. Zazueta,et al.  Redox activation of Nrf2 & NF-κB: a double end sword? , 2013, Cellular signalling.

[25]  S. Hwang,et al.  Resolvins: Endogenously-Generated Potent Painkilling Substances and their Therapeutic Perspectives , 2013, Current neuropharmacology.

[26]  K. Gronert,et al.  Systemic Disease during Streptococcus pneumoniae Acute Lung Infection Requires 12-Lipoxygenase–Dependent Inflammation , 2013, The Journal of Immunology.

[27]  B. Fox,et al.  Kinetic and structural investigations into the allosteric and pH effect on the substrate specificity of human epithelial 15-lipoxygenase-2. , 2013, Biochemistry.

[28]  B. Halliwell,et al.  Augmentation of 5-lipoxygenase activity and expression during dengue serotype-2 infection , 2013, Virology Journal.

[29]  P. Reddanna,et al.  15(S)-HETE-induced angiogenesis in adipose tissue is mediated through activation of PI3K/Akt/mTOR signaling pathway. , 2013, Biochemistry and cell biology = Biochimie et biologie cellulaire.

[30]  F. Ducharme,et al.  Addition of anti-leukotriene agents to inhaled corticosteroids in children with persistent asthma. , 2013, The Cochrane database of systematic reviews.

[31]  J. Rokach,et al.  The eosinophil chemoattractant 5-oxo-ETE and the OXE receptor. , 2013, Progress in lipid research.

[32]  T. V. Van Dyke,et al.  Natural resolution of inflammation. , 2013, Periodontology 2000.

[33]  K. Bishayee,et al.  5-lipoxygenase antagonist therapy: a new approach towards targeted cancer chemotherapy. , 2013, Acta biochimica et biophysica Sinica.

[34]  A. Brunet,et al.  Leukotriene B4, an Endogenous Stimulator of the Innate Immune Response against Pathogens , 2013, Journal of Innate Immunity.

[35]  A. Oliver,et al.  Structure and interaction with phospholipids of a prokaryotic lipoxygenase from Pseudomonas aeruginosa , 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[36]  B. Brüne,et al.  Redox control of inflammation in macrophages. , 2013, Antioxidants & redox signaling.

[37]  C. Serhan,et al.  Resolution phase lipid mediators of inflammation: agonists of resolution. , 2013, Current opinion in pharmacology.

[38]  M. Lagarde,et al.  Characterization and biological effects of di-hydroxylated compounds deriving from the lipoxygenation of ALA , 2013, Journal of Lipid Research.

[39]  A. Ray,et al.  A review on leukotrienes and their receptors with reference to asthma , 2013, The Journal of asthma : official journal of the Association for the Care of Asthma.

[40]  Y. Bayazıt,et al.  Expression of Cyclooxygenase-2, 12-Lipoxygenase, and Inducible Nitric Oxide Synthase in Head and Neck Squamous Cell Carcinoma , 2013, The Journal of craniofacial surgery.

[41]  A. Dobrian,et al.  12- and 15-lipoxygenases in adipose tissue inflammation. , 2013, Prostaglandins & other lipid mediators.

[42]  A. Jadhav,et al.  12-lipoxygenase activity plays an important role in PAR4 and GPVI-mediated platelet reactivity , 2013, Thrombosis and Haemostasis.

[43]  D. Steinhilber,et al.  5-Lipoxygenase inhibitors: a review of recent patents (2010 – 2012) , 2013, Expert opinion on therapeutic patents.

[44]  C. Serhan,et al.  Novel n-3 Immunoresolvents: Structures and Actions , 2013, Scientific Reports.

[45]  Zhennan Gu,et al.  Mechanisms of Omega-3 Polyunsaturated Fatty Acids in Prostate Cancer Prevention , 2013, BioMed research international.

[46]  Gene Kim,et al.  The role of redox signaling in epigenetics and cardiovascular disease. , 2013, Antioxidants & redox signaling.

[47]  E. Dennis,et al.  Systematic analysis of rat 12/15‐lipoxygenase enzymes reveals critical role for spinal eLOX3 hepoxilin synthase activity in inflammatory hyperalgesia , 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[48]  J. Neels.  A role for 5-lipoxygenase products in obesity-associated inflammation and insulin resistance , 2013, Adipocyte.

[49]  A. Garreta,et al.  Bacterial lipoxygenases, a new subfamily of enzymes? A phylogenetic approach , 2013, Applied Microbiology and Biotechnology.

[50]  R. Haynes,et al.  12/15-Lipoxygenase Expression Is Increased in Oligodendrocytes and Microglia of Periventricular Leukomalacia , 2013, Developmental Neuroscience.

[51]  J. Filep,et al.  Modulation of Neutrophil Apoptosis and the Resolution of Inflammation through β2 Integrins , 2013, Front. Immunol..

[52]  E. Tremoli,et al.  Eicosanoids and Their Drugs in Cardiovascular Diseases: Focus on Atherosclerosis and Stroke , 2013, Medicinal research reviews.

[53]  S. Tersey,et al.  Deletion of 12/15-Lipoxygenase Alters Macrophage and Islet Function in NOD-Alox15null Mice, Leading to Protection against Type 1 Diabetes Development , 2013, PloS one.

[54]  D. Aronoff,et al.  Leukotriene B4 Enhances Innate Immune Defense against the Puerperal Sepsis Agent Streptococcus pyogenes , 2013, The Journal of Immunology.

[55]  J. Klinman.  Importance of protein dynamics during enzymatic C-H bond cleavage catalysis. , 2013, Biochemistry.

[56]  E. Toskala,et al.  Role of Leukotriene Antagonists and Antihistamines in the Treatment of Allergic Rhinitis , 2013, Current Allergy and Asthma Reports.

[57]  M. Rossi,et al.  5-Lipoxygenase Activity Increases Susceptibility to Experimental Paracoccidioides brasiliensis Infection , 2013, Infection and Immunity.

[58]  I. Perrotta.  Ultrastructural Features of Human Atherosclerosis , 2013, Ultrastructural pathology.

[59]  E. Lo,et al.  Following experimental stroke, the recovering brain is vulnerable to lipoxygenase‐dependent semaphorin signaling , 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[60]  Emiri T. Mandeville,et al.  Inhibition of 12/15‐lipoxygenase as therapeutic strategy to treat stroke , 2013, Annals of neurology.

[61]  M. Rauh,et al.  Aloxe3 knockout mice reveal a function of epidermal lipoxygenase-3 as hepoxilin synthase and its pivotal role in barrier formation. , 2013, The Journal of investigative dermatology.

[62]  S. Goswami.  Cellular redox, epigenetics and diseases. , 2013, Sub-cellular biochemistry.

[63]  R. Kornowski,et al.  Elevated level of pro-inflammatory eicosanoids and EPC dysfunction in diabetic patients with cardiac ischemia. , 2013, Prostaglandins & other lipid mediators.

[64]  J. O'flaherty,et al.  15-Lipoxygenase-1-mediated metabolism of docosahexaenoic acid is required for syndecan-1 signaling and apoptosis in prostate cancer cells. , 2013, Carcinogenesis.

[65]  K. van Leyen.  Lipoxygenase: an emerging target for stroke therapy. , 2013, CNS & neurological disorders drug targets.

[66]  R. Buckley,et al.  Leukotriene receptor antagonists in allergic eye disease: a systematic review and meta-analysis. , 2013, The journal of allergy and clinical immunology. In practice.

[67]  H. Kuang,et al.  12(S)-hydroxyeicosatetraenoic acid levels link to coronary artery disease in Type 2 diabetic patients , 2013, Journal of Endocrinological Investigation.

[68]  M. Tavakoli-Yaraki,et al.  Induction of apoptosis by Trichostatin A in human breast cancer cell lines: involvement of 15-Lox-1 , 2013, Tumor Biology.

[69]  V. Turcanu,et al.  Role of Leukotriene Receptor Antagonists in the Management of Pediatric Asthma , 2012, Pediatric Drugs.

[70]  A. Nakajima,et al.  Role of leukotriene B₄ receptor signaling in human preadipocyte differentiation. , 2012, Biochemical and biophysical research communications.

[71]  Y. Surh,et al.  Therapeutic potential of resolvins in the prevention and treatment of inflammatory disorders. , 2012, Biochemical pharmacology.

[72]  J. Chiu,et al.  Redox control of cell proliferation. , 2012, Trends in cell biology.

[73]  B. Toursarkissian,et al.  Tissue markers in human atherosclerotic carotid artery plaque. , 2012, Annals of vascular surgery.

[74]  V. Turcanu,et al.  Role of leukotriene receptor antagonists in the management of pediatric asthma: an update. , 2012, Paediatric drugs.

[75]  G. Melino,et al.  Novel transglutaminase 1 mutations in patients affected by lamellar ichthyosis , 2012, Cell Death and Disease.

[76]  J. O'flaherty,et al.  15-Lipoxygenase Metabolites of Docosahexaenoic Acid Inhibit Prostate Cancer Cell Proliferation and Survival , 2012, PloS one.

[77]  Shu Xu,et al.  Crystal structure of 12-lipoxygenase catalytic-domain-inhibitor complex identifies a substrate-binding channel for catalysis. , 2012, Structure.

[78]  J. Boyce,et al.  Cysteinyl leukotriene receptors, old and new; implications for asthma , 2012, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[79]  D. Hohl,et al.  The human epidermal differentiation complex: cornified envelope precursors, S100 proteins and the ‘fused genes’ family , 2012, Experimental dermatology.

[80]  Polamarasetty Aparoy,et al.  Structure and Ligand Based Drug Design Strategies in the Development of Novel 5-LOX Inhibitors , 2012, Current medicinal chemistry.

[81]  D. Atochin,et al.  A Novel Hydrogen Sulfide-releasing N-Methyl-d-Aspartate Receptor Antagonist Prevents Ischemic Neuronal Death* , 2012, The Journal of Biological Chemistry.

[82]  A. Obenaus,et al.  Novel aspirin-triggered neuroprotectin D1 attenuates cerebral ischemic injury after experimental stroke , 2012, Experimental Neurology.

[83]  E. Massey,et al.  The ins and outs of human reticulocyte maturation , 2012, Autophagy.

[84]  W. Campbell,et al.  Mice lacking macrophage 12/15-lipoxygenase are resistant to experimental hypertension. , 2012, American journal of physiology. Heart and circulatory physiology.

[85]  Michal Hammel,et al.  Validation of macromolecular flexibility in solution by small-angle X-ray scattering (SAXS) , 2012, European Biophysics Journal.

[86]  F. Ducharme,et al.  Anti-leukotriene agents compared to inhaled corticosteroids in the management of recurrent and/or chronic asthma in adults and children. , 2012, The Cochrane database of systematic reviews.

[87]  Colin McCann,et al.  LTB4 is a signal-relay molecule during neutrophil chemotaxis. , 2012, Developmental cell.

[88]  A. Brash,et al.  Conversion of human 5‐lipoxygenase to a 15‐lipoxygenase by a point mutation to mimic phosphorylation at Serine‐663 , 2012 .

[89]  D. Svergun,et al.  Ligand‐induced formation of transient dimers of mammalian 12/15‐lipoxygenase: A key to allosteric behavior of this class of enzymes? , 2012, Proteins.

[90]  M. Fornage,et al.  No association of ALOX5AP polymorphisms with risk of MRI-defined brain infarcts , 2012, Neurobiology of Aging.

[91]  A. Jadhav,et al.  Protein Kinase C Regulation of 12-Lipoxygenase-Mediated Human Platelet Activation , 2012, Molecular Pharmacology.

[92]  Daling Zhu,et al.  Role of 15-lipoxygenase/15-hydroxyeicosatetraenoic acid in hypoxia-induced pulmonary hypertension , 2012, The Journal of Physiological Sciences.

[93]  C. Serhan,et al.  Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain , 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[94]  Q. Mao-Ying,et al.  Lipoxins and aspirin-triggered lipoxin alleviate bone cancer pain in association with suppressing expression of spinal proinflammatory cytokines , 2012, Journal of Neuroinflammation.

[95]  P. Möller,et al.  NF-κB signaling in prostate cancer: A promising therapeutic target? , 2012, World Journal of Urology.

[96]  Jie Wang,et al.  A Lipoxin A4 Analog Ameliorates Blood–Brain Barrier Dysfunction and Reduces MMP-9 Expression in a Rat Model of Focal Cerebral Ischemia–Reperfusion Injury , 2011, Journal of Molecular Neuroscience.

[97]  T. Yokomizo.  Leukotriene B4 receptors: novel roles in immunological regulations. , 2011, Advances in enzyme regulation.

[98]  M. Hamberg,et al.  Targeted knock-down of a structurally atypical zebrafish 12S-lipoxygenase leads to severe impairment of embryonic development , 2011, Proceedings of the National Academy of Sciences.

[99]  J. Lysaght,et al.  Eicosanoid signalling pathways in the development and progression of colorectal cancer: novel approaches for prevention/intervention , 2011, Cancer and Metastasis Reviews.

[100]  C. Brodie,et al.  Inhibition of 5-lipoxygenase triggers apoptosis in prostate cancer cells via down-regulation of protein kinase C-epsilon. , 2011, Biochimica et biophysica acta.

[101]  G. Schneider,et al.  Dimerization of human 5-lipoxygenase , 2011, Biological chemistry.

[102]  C. Rao,et al.  Role of lipoxins, resolvins, and other bioactive lipids in colon and pancreatic cancer , 2011, Cancer and Metastasis Reviews.

[103]  Claus Schneider,et al.  Cyclooxygenases and lipoxygenases in cancer , 2011, Cancer and Metastasis Reviews.

[104]  C. Serhan,et al.  Resolvins and protectins in inflammation resolution. , 2011, Chemical reviews.

[105]  A. Mancini,et al.  The cardinal role of the phospholipase A2/cyclooxygenase-2/prostaglandin E synthase/prostaglandin E2 (PCPP) axis in inflammostasis , 2011, Inflammation Research.

[106]  J. Haeggström,et al.  Lipoxygenase and leukotriene pathways: biochemistry, biology, and roles in disease. , 2011, Chemical reviews.

[107]  I. Cimen,et al.  15‐lipoxygenase‐1 exerts its tumor suppressive role by inhibiting nuclear factor‐kappa B via activation of PPAR gamma , 2011, Journal of cellular biochemistry.

[108]  A. Jadhav,et al.  Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase. , 2011, Journal of medicinal chemistry.

[109]  R. Mcivor,et al.  Montelukast for the treatment of asthma in the adult population , 2011, Expert opinion on pharmacotherapy.

[110]  S. Rapoport,et al.  Altered neuroinflammatory, arachidonic acid cascade and synaptic markers in postmortem Alzheimer's disease brain , 2011, Translational Psychiatry.

[111]  M. Holinstat,et al.  12-lipoxygenase: a potential target for novel anti-platelet therapeutics. , 2011, Cardiovascular & hematological agents in medicinal chemistry.

[112]  D. Svergun,et al.  Probing dimerization and structural flexibility of mammalian lipoxygenases by small-angle X-ray scattering. , 2011, Journal of molecular biology.

[113]  S. Nigam,et al.  Hepoxilin A(3) protects β-cells from apoptosis in contrast to its precursor, 12-hydroperoxyeicosatetraenoic acid. , 2011, Biochimica et biophysica acta.

[114]  D. Beier,et al.  Lipoxygenases Mediate the Effect of Essential Fatty Acid in Skin Barrier Formation , 2011, The Journal of Biological Chemistry.

[115]  A. Gabrielsen,et al.  12- and 15-lipoxygenases in human carotid atherosclerotic lesions: associations with cerebrovascular symptoms. , 2011, Atherosclerosis.

[116]  R. Sattar,et al.  Molecular dynamics simulation of mammalian 15S-lipoxygenase with AMBER force field , 2011, European Biophysics Journal.

[117]  N. Plesnila,et al.  Bid-mediated mitochondrial damage is a key mechanism in glutamate-induced oxidative stress and AIF-dependent cell death in immortalized HT-22 hippocampal neurons , 2011, Cell Death and Differentiation.

[118]  A. Brash,et al.  The Structure of Human 5-Lipoxygenase , 2011, Science.

[119]  M. Lagarde,et al.  Poxytrins, a class of oxygenated products from polyunsaturated fatty acids, potently inhibit blood platelet aggregation , 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[120]  H. Zhang,et al.  ALOX12 polymorphisms are associated with fat mass but not peak bone mineral density in Chinese nuclear families , 2010, International Journal of Obesity.

[121]  A. Dobrian,et al.  Functional and pathological roles of the 12- and 15-lipoxygenases. , 2011, Progress in lipid research.

[122]  Jiali Gu,et al.  Evidence for activation of inflammatory lipoxygenase pathways in visceral adipose tissue of obese Zucker rats. , 2011, American journal of physiology. Endocrinology and metabolism.

[123]  B. Binder,et al.  Oxidized Phospholipids Are More Potent Antagonists of Lipopolysaccharide than Inducers of Inflammation , 2010, The Journal of Immunology.

[124]  D. Ye,et al.  Depletion of Regulatory T Cells Facilitates Growth of Established Tumors: A Mechanism Involving the Regulation of Myeloid-Derived Suppressor Cells by Lipoxin A4 , 2010, The Journal of Immunology.

[125]  Valerie B. O’Donnell,et al.  Molecular enzymology of lipoxygenases. , 2010, Archives of biochemistry and biophysics.

[126]  Jia-min Zhuo,et al.  Amelioration of the Alzheimer's Disease Phenotype by Absence of 12/15-Lipoxygenase , 2010, Biological Psychiatry.

[127]  A. Obenaus,et al.  Docosahexaenoic Acid Therapy of Experimental Ischemic Stroke , 2010, Translational Stroke Research.

[128]  A. Jadhav,et al.  Discovery of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1. , 2010, Journal of medicinal chemistry.

[129]  A. Brash,et al.  On the Role of Molecular Oxygen in Lipoxygenase Activation , 2010, The Journal of Biological Chemistry.

[130]  A. Brash,et al.  Dioxygenase Activity of Epidermal Lipoxygenase-3 Unveiled , 2010, The Journal of Biological Chemistry.

[131]  K. Carlsen,et al.  Eoxins: a new inflammatory pathway in childhood asthma. , 2010, The Journal of allergy and clinical immunology.

[132]  G. Bornkamm,et al.  12/15-lipoxygenase–derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases , 2010, Proceedings of the National Academy of Sciences.

[133]  M. Hersberger.  Potential role of the lipoxygenase derived lipid mediators in atherosclerosis: leukotrienes, lipoxins and resolvins , 2010, Clinical chemistry and laboratory medicine.

[134]  Jeffrey S. Morris,et al.  Profiling Lipoxygenase Metabolism in Specific Steps of Colorectal Tumorigenesis , 2010, Cancer Prevention Research.

[135]  M. Kaczmarczyk,et al.  Overexpression of 5-lipoxygenase in sporadic colonic adenomas and a possible new aspect of colon carcinogenesis , 2010, International Journal of Colorectal Disease.

[136]  K. Kristiansen,et al.  Epidermis-Type Lipoxygenase 3 Regulates Adipocyte Differentiation and Peroxisome Proliferator-Activated Receptor γ Activity , 2010, Molecular and Cellular Biology.

[137]  M. Romano.  Lipoxin and Aspirin-Triggered Lipoxins , 2010, TheScientificWorldJournal.

[138]  A. Ray,et al.  Cysteinyl Leukotrienes and Their Receptors: Molecular and Functional Characteristics , 2010, Pharmacology.

[139]  Hong Wu,et al.  Downregulation of 15-lipoxygenase 2 by glucocorticoid receptor in prostate cancer cells. , 2010, International journal of oncology.

[140]  C. Myers,et al.  MK591, a leukotriene biosynthesis inhibitor, induces apoptosis in prostate cancer cells: synergistic action with LY294002, an inhibitor of phosphatidylinositol 3'-kinase. , 2010, Cancer letters.

[141]  B. Samuelsson,et al.  Regulation of the activity of 5-lipoxygenase, a key enzyme in leukotriene biosynthesis. , 2010, Biochemical and biophysical research communications.

[142]  D. Ferguson,et al.  Mitochondrial clearance by autophagy in developing erythrocytes: Clearly important, but just how much so? , 2010, Cell cycle.

[143]  D. Kusewitt,et al.  TRANSGENIC EXPRESSION OF 15-LIPOXYGENASE 2 (15-LOX2) IN MOUSE PROSTATE LEADS TO HYPERPLASIA AND CELL SENESCENCE , 2010, Oncogene.

[144]  C. Funk,et al.  The 5-lipoxygenase/leukotriene pathway in preclinical models of cardiovascular disease. , 2010, Cardiovascular research.

[145]  Gregory J. Hardy,et al.  Pharmacological inhibition of BLT1 diminishes early abdominal aneurysm formation. , 2010, Atherosclerosis.

[146]  R. Murphy,et al.  Transcellular biosynthesis of eicosanoids , 2010, Pharmacological reports : PR.

[147]  C. Godson,et al.  Lipoxins: regulators of resolution. , 2010, Current opinion in pharmacology.

[148]  J. Ferro,et al.  Association of a Genetic Variant in the ALOX5AP with Higher Risk of Ischemic Stroke: A Case-Control, Meta-Analysis and Functional Study , 2010, Cerebrovascular Diseases.

[149]  Ruei-Jiun Hung,et al.  Mical links semaphorins to F-actin disassembly , 2010, Nature.

[150]  S. Siegelbaum,et al.  12-Lipoxygenase Regulates Hippocampal Long-Term Potentiation by Modulating L-Type Ca2+ Channels , 2010, The Journal of Neuroscience.

[151]  J. Nadler,et al.  12-Lipoxygenase Products Reduce Insulin Secretion and {beta}-Cell Viability in Human Islets. , 2010, The Journal of clinical endocrinology and metabolism.

[152]  J. Fischer,et al.  Genotypic and clinical spectrum of self-improving collodion ichthyosis: ALOX12B, ALOXE3, and TGM1 mutations in Scandinavian patients. , 2010, The Journal of investigative dermatology.

[153]  D. Fairlie,et al.  Inflammatory lipid mediators in adipocyte function and obesity , 2010, Nature Reviews Endocrinology.

[154]  K. Arai,et al.  Increased Nuclear Apoptosis-Inducing Factor after Transient Focal Ischemia: A 12/15-Lipoxygenase-dependent Organelle Damage Pathway , 2010, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[155]  B. Fagerberg,et al.  15‐Lipoxygenase‐2 is expressed in macrophages in human carotid plaques and regulated by hypoxia‐inducible factor‐1α , 2010, European journal of clinical investigation.

[156]  P. Reddanna,et al.  Applicability of the Triad Concept for the Positional Specificity of Mammalian Lipoxygenases* , 2009, The Journal of Biological Chemistry.

[157]  Sreeparna Banerjee,et al.  15‐Lipoxygenase‐1 expression suppresses the invasive properties of colorectal carcinoma cell lines HCT‐116 and HT‐29 , 2009, Cancer science.

[158]  C. Serhan,et al.  Resolvin E1 Receptor Activation Signals Phosphorylation and Phagocytosis* , 2009, The Journal of Biological Chemistry.

[159]  K. Arai,et al.  12/15‐Lipoxygenase targets neuronal mitochondria under oxidative stress , 2009, Journal of neurochemistry.

[160]  Elizabeth L. Cureton,et al.  Lipoxin a(4) attenuates microvascular fluid leak during inflammation. , 2009, The Journal of surgical research.

[161]  C. Pace-Asciak.  The hepoxilins and some analogues: a review of their biology , 2009, British journal of pharmacology.

[162]  Dorothy D. Sears,et al.  12/15-Lipoxygenase Is Required for the Early Onset of High Fat Diet-Induced Adipose Tissue Inflammation and Insulin Resistance in Mice , 2009, PloS one.

[163]  Joshua D Deschamps,et al.  Kinetic and structural investigations of the allosteric site in human epithelial 15-lipoxygenase-2. , 2009, Biochemistry.

[164]  T. Holman,et al.  Substrate specificity effects of lipoxygenase products and inhibitors on soybean lipoxygenase-1. , 2009, Bioorganic & medicinal chemistry.

[165]  S. Keller,et al.  12/15‐Lipoxygenase Products Induce Inflammation and Impair Insulin Signaling in 3T3‐L1 Adipocytes , 2009, Obesity.

[166]  L. Joosten,et al.  12/15-Lipoxygenase Counteracts Inflammation and Tissue Damage in Arthritis , 2009, The Journal of Immunology.

[167]  W. Campbell,et al.  Role of arachidonic acid lipoxygenase metabolites in the regulation of vascular tone. , 2009, American journal of physiology. Heart and circulatory physiology.

[168]  T. Holman,et al.  Mechanistic investigations of human reticulocyte 15- and platelet 12-lipoxygenases with arachidonic acid. , 2009, Biochemistry.

[169]  A. Parwani,et al.  Prostate tumor growth can be modulated by dietarily targeting the 15-lipoxygenase-1 and cyclooxygenase-2 enzymes. , 2009, Neoplasia.

[170]  Jesse C. Gatlin,et al.  Dynamic adhesions and MARCKS in melanoma cells , 2009, Journal of Cell Science.

[171]  R. Murphy,et al.  Dual 12/15- and 5-Lipoxygenase Deficiency in Macrophages Alters Arachidonic Acid Metabolism and Attenuates Peritonitis and Atherosclerosis in ApoE Knock-out Mice* , 2009, The Journal of Biological Chemistry.

[172]  H. Hennies,et al.  Molecular analysis of 250 patients with autosomal recessive congenital ichthyosis: evidence for mutation hotspots in ALOXE3 and allelic heterogeneity in ALOX12B. , 2009, The Journal of investigative dermatology.

[173]  A. Heller,et al.  Anticancer actions of omega-3 fatty acids--current state and future perspectives. , 2009, Anti-cancer agents in medicinal chemistry.

[174]  I. Feussner,et al.  Biosynthesis of oxylipins in non-mammals. , 2009, Progress in lipid research.

[175]  S. Gnyawali,et al.  Glutathione disulfide induces neural cell death via a 12-lipoxygenase pathway , 2009, Cell Death and Differentiation.

[176]  Downregulation of vascular endothelial growth factor and induction of tumor dormancy by 15‐lipoxygenase‐2 in prostate cancer , 2009, International journal of cancer.

[177]  D. Steinberg.  The LDL modification hypothesis of atherogenesis: an update Published, JLR Papers in Press, November 15, 2009. , 2009, Journal of Lipid Research.

[178]  O. Hurtado,et al.  Synthesis of Lipoxin A4 by 5-Lipoxygenase Mediates PPARγ-Dependent, Neuroprotective Effects of Rosiglitazone in Experimental Stroke , 2009, The Journal of Neuroscience.

[179]  R. Bataller,et al.  Increased susceptibility to exacerbated liver injury in hypercholesterolemic ApoE-deficient mice: potential involvement of oxysterols. , 2009, American journal of physiology. Gastrointestinal and liver physiology.

[180]  W. Campbell,et al.  Chronic hypoxia enhances 15-lipoxygenase-mediated vasorelaxation in rabbit arteries. , 2009, American journal of physiology. Heart and circulatory physiology.

[181]  G. Schett,et al.  The 12/15-lipoxygenase pathway promotes osteoclast development and differentiation , 2009, Autoimmunity.

[182]  Harry Martin.  Role of PPAR-gamma in inflammation. Prospects for therapeutic intervention by food components. , 2009, Mutation research.

[183]  J. Brandner,et al.  The skin: an indispensable barrier , 2008, Experimental dermatology.

[184]  W. Campbell,et al.  Hypercholesterolemia Enhances 15-Lipoxygenase–Mediated Vasorelaxation and Acetylcholine-Induced Hypotension , 2008, Arteriosclerosis, thrombosis, and vascular biology.

[185]  R. Yoshimura,et al.  The target of arachidonic acid pathway is a new anticancer strategy for human prostate cancer , 2008, Biologics : targets & therapy.

[186]  C. Serhan,et al.  Atherosclerosis: evidence for impairment of resolution of vascular inflammation governed by specific lipid mediators , 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[187]  Meng Chen,et al.  12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by Western diet. , 2008, American journal of physiology. Endocrinology and metabolism.

[188]  N. Plesnila,et al.  Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death. , 2008, Cell metabolism.

[189]  D. Bentrem,et al.  Overexpression of 5-Lipoxygenase in Colon Polyps and Cancer and the Effect of 5-LOX Inhibitors In vitro and in a Murine Model , 2008, Clinical Cancer Research.

[190]  K. Arai,et al.  Protecting Against Cerebrovascular Injury: Contributions of 12/15-Lipoxygenase to Edema Formation After Transient Focal Ischemia , 2008, Stroke.

[191]  G. Mei,et al.  Structural properties of plant and mammalian lipoxygenases. Temperature-dependent conformational alterations and membrane binding ability. , 2008, Biochemistry.

[192]  Joshua D Deschamps,et al.  Substrate specificity changes for human reticulocyte and epithelial 15-lipoxygenases reveal allosteric product regulation. , 2008, Biochemistry.

[193]  J. Borén,et al.  15-Lipoxygenase-2 expression in human macrophages induces chemokine secretion and T cell migration. , 2008, Atherosclerosis.

[194]  Jeffrey S. Morris,et al.  Therapeutic molecular targeting of 15-lipoxygenase-1 in colon cancer. , 2008, Molecular therapy : the journal of the American Society of Gene Therapy.

[195]  T. Meitinger,et al.  Genetic Variation in Members of the Leukotriene Biosynthesis Pathway Confer an Increased Risk of Ischemic Stroke: A Replication Study in Two Independent Populations , 2008, Stroke.

[196]  T. Wisniewski,et al.  5‐Lipoxygenase gene disruption reduces amyloid‐β pathology in a mouse model of Alzheimer's disease , 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[197]  K. Arai,et al.  Novel lipoxygenase inhibitors as neuroprotective reagents , 2008, Journal of neuroscience research.

[198]  Sangsoo Kim,et al.  Conformational flexibility in mammalian 15S‐lipoxygenase: Reinterpretation of the crystallographic data , 2008, Proteins.

[199]  D. Svergun,et al.  Human platelet 12-lipoxygenase, new findings about its activity, membrane binding and low-resolution structure. , 2008, Journal of molecular biology.

[200]  Jilly F. Evans,et al.  What's all the FLAP about?: 5-lipoxygenase-activating protein inhibitors for inflammatory diseases. , 2008, Trends in pharmacological sciences.

[201]  G. Weisinger,et al.  Lipoxygenase-derived metabolites are regulators of peroxisome proliferator-activated receptor gamma-2 expression in human vascular smooth muscle cells. , 2008, American journal of hypertension.

[202]  W. Campbell,et al.  Endothelial 15-Lipoxygenase-1 Overexpression Increases Acetylcholine-Induced Hypotension and Vasorelaxation in Rabbits , 2008, Hypertension.

[203]  R. Neve,et al.  Hyperoxia Causes Maturation-Dependent Cell Death in the Developing White Matter , 2008, The Journal of Neuroscience.

[204]  J. Haeggström,et al.  Human CMV infection induces 5-lipoxygenase expression and leukotriene B4 production in vascular smooth muscle cells , 2008, The Journal of experimental medicine.

[205]  S. Tersey,et al.  Nonobese Diabetic (NOD) Mice Congenic for a Targeted Deletion of 12/15-Lipoxygenase Are Protected From Autoimmune Diabetes , 2008, Diabetes.

[206]  Yan Lu,et al.  Candida albicans Modulates Host Defense by Biosynthesizing the Pro-Resolving Mediator Resolvin E1 , 2007, PloS one.

[207]  J. Gulcher,et al.  PDE4D and ALOX5AP genetic variants and risk for Ischemic Cerebrovascular Disease in Sweden , 2007, Journal of the Neurological Sciences.

[208]  H. Kuhn,et al.  15-Lipoxygenase-2 is differentially expressed in normal and neoplastic ovary , 2007, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation.

[209]  H. Kuhn,et al.  Arachidonic Acid Metabolites in the Cardiovascular System: The Role of Lipoxygenase Isoforms in Atherogenesis With Particular Emphasis on Vascular Remodeling , 2007, Journal of cardiovascular pharmacology.

[210]  A. Hoffman,et al.  Leukotriene B4 receptor antagonists as therapeutics for inflammatory disease: preclinical and clinical developments , 2007, Expert opinion on investigational drugs.

[211]  M. Vidal,et al.  Reticulocyte-secreted exosomes bind natural IgM antibodies: involvement of a ROS-activatable endosomal phospholipase iPLA2. , 2007, Blood.

[212]  A. Bonfigli,et al.  Increased expression of 5-lipoxygenase is common in clear cell renal cell carcinoma. , 2007, Histology and histopathology.

[213]  L. Ghibelli,et al.  Involvement of 5-lipoxygenase in survival of Epstein-Barr virus (EBV)-converted B lymphoma cells. , 2007, Cancer letters.

[214]  G. Rogler,et al.  13-Oxo-ODE is an endogenous ligand for PPARγ in human colonic epithelial cells , 2007 .

[215]  M. Hersberger,et al.  The two faces of the 15-lipoxygenase in atherosclerosis. , 2007, Prostaglandins, leukotrienes, and essential fatty acids.

[216]  C. Funk,et al.  Angiotensin II-induced abdominal aortic aneurysm occurs independently of the 5-lipoxygenase pathway in apolipoprotein E-deficient mice. , 2007, Prostaglandins & other lipid mediators.

[217]  S. Nigam,et al.  Structure, biochemistry and biology of hepoxilins , 2007, The FEBS journal.

[218]  O. Werz,et al.  5-Lipoxygenase: regulation of expression and enzyme activity. , 2007, Trends in biochemical sciences.

[219]  R. Gerszten,et al.  Inhibited Aortic Aneurysm Formation in BLT1-Deficient Mice1 , 2007, The Journal of Immunology.

[220]  A. Brash,et al.  The hepoxilin connection in the epidermis , 2007, The FEBS journal.

[221]  Y. Kawahito,et al.  Overexpression of cysteinyl LT1 receptor in prostate cancer and CysLT1R antagonist inhibits prostate cancer cell growth through apoptosis. , 2007, Oncology reports.

[222]  E. Abel,et al.  Diabetic cardiomyopathy revisited. , 2007, Circulation.

[223]  G. Schmitz,et al.  12R-lipoxygenase deficiency disrupts epidermal barrier function , 2007, The Journal of cell biology.

[224]  W. Berger,et al.  Zileuton: clinical implications of 5‐Lipoxygenase inhibition in severe airway disease , 2007, International journal of clinical practice.

[225]  J. Broderick,et al.  Association of ALOX5AP with ischemic stroke: a population-based case-control study , 2007, Human Genetics.

[226]  S. Hammes-Schiffer,et al.  Proton-coupled electron transfer in soybean lipoxygenase: dynamical behavior and temperature dependence of kinetic isotope effects. , 2007, Journal of the American Chemical Society.

[227]  W. Campbell,et al.  Abstract 650: Adenoviral Expression of 15-Lipoxygenase-1 in Rabbit Aortic Endothelium: Role in Arachidonic Acid-Induced Relaxation , 2006 .

[228]  R. Schneider-Broussard,et al.  15-lipoxygenase 2 (15-LOX2) is a functional tumor suppressor that regulates human prostate epithelial cell differentiation, senescence, and growth (size). , 2007, Prostaglandins & other lipid mediators.

[229]  G. Rogler,et al.  13-Oxo-ODE is an endogenous ligand for PPARgamma in human colonic epithelial cells. , 2007, Biochemical pharmacology.

[230]  D. Heydeck,et al.  Regulation of cellular 15-lipoxygenase activity on pretranslational, translational, and posttranslational levels , 2007, Lipids.

[231]  Hirokazu Takahashi,et al.  Blockade of leukotriene B4 signaling pathway induces apoptosis and suppresses cell proliferation in colon cancer. , 2007, Journal of pharmacological sciences.

[232]  K. Arai,et al.  Baicalein and 12/15-Lipoxygenase in the Ischemic Brain , 2006, Stroke.

[233]  A. Brash,et al.  Human and mouse eLOX3 have distinct substrate specificities: implications for their linkage with lipoxygenases in skin. , 2006, Archives of biochemistry and biophysics.

[234]  Luc Kestens,et al.  Human schistosomiasis , 2006, The Lancet.

[235]  A. Sabichi,et al.  15-Lipoxygenase-2 gene regulation by its product 15-(S)-hydroxyeicosatetraenoic acid through a negative feedback mechanism that involves peroxisome proliferator-activated receptor γ , 2006, Oncogene.

[236]  T. Shirahama,et al.  Inhibition of 5‐lipoxygenase pathway suppresses the growth of bladder cancer cells , 2006, International journal of urology : official journal of the Japanese Urological Association.

[237]  W. D. Martin,et al.  Conditional expression of human 15-lipoxygenase-1 in mouse prostate induces prostatic intraepithelial neoplasia: the FLiMP mouse model. , 2006, Neoplasia.

[238]  Anders Gabrielsen,et al.  Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[239]  M. Akiyama.  Harlequin ichthyosis and other autosomal recessive congenital ichthyoses: the underlying genetic defects and pathomechanisms. , 2006, Journal of dermatological science.

[240]  M. Romano.  Lipid mediators: lipoxin and aspirin-triggered 15-epi-lipoxins. , 2006, Inflammation & allergy drug targets.

[241]  M. Mangino,et al.  Lipoxin biosynthesis in inflammatory bowel disease. , 2006, Prostaglandins & other lipid mediators.

[242]  H. Kuhn,et al.  15-Lipoxygenase-mediated modification of high-density lipoproteins impairs SR-BI- and ABCA1-dependent cholesterol efflux from macrophages. , 2006, Biochimica et biophysica acta.

[243]  H. Kuhn,et al.  Reticulocyte 15-Lipoxygenase-I Is Important in Acetylcholine-Induced Endothelium-Dependent Vasorelaxation in Rabbit Aorta , 2006, Arteriosclerosis, thrombosis, and vascular biology.

[244]  D. Rader,et al.  12/15-Lipoxygenase gene disruption and vitamin E administration diminish atherosclerosis and oxidative stress in apolipoprotein E deficient mice through a final common pathway. , 2005, Prostaglandins & other lipid mediators.

[245]  P. Reddanna,et al.  Sequence Determinants for the Reaction Specificity of Murine (12R)-Lipoxygenase , 2005, Journal of Biological Chemistry.

[246]  H. Kühn,et al.  The role of lipoxygenase-isoforms in atherogenesis. , 2005, Molecular nutrition & food research.

[247]  Charles N Serhan,et al.  A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease. , 2005, The Journal of clinical investigation.

[248]  H. Hennies,et al.  Mutation spectrum and functional analysis of epidermis‐type lipoxygenases in patients with autosomal recessive congenital ichthyosis , 2005, Human mutation.

[249]  J. Trojanowski,et al.  Elevation of 12/15 lipoxygenase products in AD and mild cognitive impairment , 2005, Annals of neurology.

[250]  C. Sen,et al.  Neuroprotective Properties of the Natural Vitamin E &agr;-Tocotrienol , 2005, Stroke.

[251]  A. Sher,et al.  Host control of Mycobacterium tuberculosis is regulated by 5-lipoxygenase-dependent lipoxin production. , 2005, The Journal of clinical investigation.

[252]  P. Vachette,et al.  Structural stability of soybean lipoxygenase-1 in solution as probed by small angle X-ray scattering. , 2005, Journal of molecular biology.

[253]  R. Newman,et al.  Cell-autonomous induction of functional tumor suppressor 15-lipoxygenase 2 (15-LOX2) contributes to replicative senescence of human prostate progenitor cells , 2005, Oncogene.

[254]  Rainer Schmidt,et al.  The cornified envelope: a model of cell death in the skin , 2005, Nature Reviews Molecular Cell Biology.

[255]  J. Nadler,et al.  Activation of 12-lipoxygenase in proinflammatory cytokine-mediated beta cell toxicity , 2005, Diabetologia.

[256]  E. Lo,et al.  Proteasome inhibition protects HT22 neuronal cells from oxidative glutamate toxicity , 2005, Journal of neurochemistry.

[257]  M. J. Smith.  Biological activities of leukotriene B4 , 1981, Agents and Actions.

[258]  Mark S. Anderson,et al.  The NOD mouse: a model of immune dysregulation. , 2005, Annual review of immunology.

[259]  Hong Wang,et al.  Peroxynitrite-Induced Neuronal Apoptosis Is Mediated by Intracellular Zinc Release and 12-Lipoxygenase Activation , 2004, The Journal of Neuroscience.

[260]  A. Krettek,et al.  Hypoxia Increases LDL Oxidation and Expression of 15-Lipoxygenase-2 in Human Macrophages , 2004, Arteriosclerosis, thrombosis, and vascular biology.

[261]  M. Hammel,et al.  Structural flexibility of the N-terminal beta-barrel domain of 15-lipoxygenase-1 probed by small angle X-ray scattering. Functional consequences for activity regulation and membrane binding. , 2004, Journal of molecular biology.

[262]  K. Ley,et al.  Critical Role of Macrophage 12/15-Lipoxygenase for Atherosclerosis in Apolipoprotein E–Deficient Mice , 2004, Circulation.

[263]  Pamela L. Follett,et al.  12‐Lipoxygenase plays a key role in cell death caused by glutathione depletion and arachidonic acid in rat oligodendrocytes , 2004, The European journal of neuroscience.

[264]  W. Wu,et al.  The Modulating Role of Nuclear Factor-κB in the Action of α7-Nicotinic Acetylcholine Receptor and Cross-Talk between 5-Lipoxygenase and Cyclooxygenase-2 in Colon Cancer Growth Induced by 4-(N-Methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone , 2004, Journal of Pharmacology and Experimental Therapeutics.

[265]  R. Neve,et al.  Nitric oxide‐induced cell death in developing oligodendrocytes is associated with mitochondrial dysfunction and apoptosis‐inducing factor translocation , 2004, The European journal of neuroscience.

[266]  S. LeVine,et al.  Experimental allergic encephalomyelitis is exacerbated in mice deficient for 12/15-lipoxygenase or 5-lipoxygenase , 2004, Brain Research.

[267]  S. Friedman,et al.  Evidence that Sp1 positively and Sp3 negatively regulate and androgen does not directly regulate functional tumor suppressor 15-lipoxygenase 2 (15-LOX2) gene expression in normal human prostate epithelial cells , 2004, Oncogene.

[268]  Jilly F. Evans,et al.  The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia-dependent aortic aneurysm , 2004, Nature Medicine.

[269]  F. Terro,et al.  Blockade of 12-lipoxygenase expression protects cortical neurons from apoptosis induced by β-amyloid peptide , 2004, Cell Death and Differentiation.

[270]  J. Eisman,et al.  Genetic determinants of bone mass , 2004, Current opinion in rheumatology.

[271]  Lei Zhao,et al.  Lipoxygenase pathways in atherogenesis. , 2004, Trends in cardiovascular medicine.

[272]  J. Trojanowski,et al.  12/15-lipoxygenase is increased in Alzheimer's disease: possible involvement in brain oxidative stress. , 2004, The American journal of pathology.

[273]  M. Hori,et al.  Cerebral ischemia in 5-lipoxygenase knockout mice , 2004, Brain Research.

[274]  J. Gulcher,et al.  The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke , 2004, Nature Genetics.

[275]  M. Balazy,et al.  Drugs that target lipoxygenases and leukotrienes as emerging therapies for asthma and cancer. , 2004, Current drug targets. Inflammation and allergy.

[276]  J. Suttles,et al.  Role of Leukotriene B4 Receptors in the Development of Atherosclerosis: Potential Mechanisms , 2004, Arteriosclerosis, thrombosis, and vascular biology.

[277]  R. DuBois,et al.  15-LOX-1 inhibits p21 (Cip/WAF 1) expression by enhancing MEK-ERK 1/2 signaling in colon carcinoma cells. , 2003, Prostaglandins & other lipid mediators.

[278]  R. DuBois,et al.  15-LOX-1 inhibits p21 (Cip/WAF 1) expression by enhancing MEK-ERK1/2 signaling in colon carcinoma cells , 2004 .

[279]  G. Hicks,et al.  Anti-leukotriene agents compared to inhaled corticosteroids in the management of recurrent and/or chronic asthma in adults and children. , 2004, The Cochrane database of systematic reviews.

[280]  Béatrice Desvergne,et al.  Peroxisome-proliferator-activated receptors and cancers: complex stories , 2004, Nature Reviews Cancer.

[281]  D. Grignon,et al.  Increased metastatic potential in human prostate carcinoma cells by overexpression of arachidonate 12-lipoxygenase , 2004, Clinical & Experimental Metastasis.

[282]  S. Siegelbaum,et al.  12-Lipoxygenase Metabolites of Arachidonic Acid Mediate Metabotropic Glutamate Receptor-Dependent Long-Term Depression at Hippocampal CA3-CA1 Synapses , 2003, The Journal of Neuroscience.

[283]  Chuan-zhen Lu,et al.  Metabolic changes of arachidonic acid after cerebral ischemia–reperfusion in diabetic rats , 2003, Experimental Neurology.

[284]  K. Kristiansen,et al.  Adipocyte differentiation of 3T3-L1 preadipocytes is dependent on lipoxygenase activity during the initial stages of the differentiation process. , 2003, The Biochemical journal.

[285]  Praveen M. Bahadduri,et al.  Molecular Basis of Vitamin E Action , 2003, Journal of Biological Chemistry.

[286]  Jeffrey S. Morris,et al.  The 15-lipoxygenase-1 product 13-S-hydroxyoctadecadienoic acid down-regulates PPAR-δ to induce apoptosis in colorectal cancer cells , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[287]  J. Ghosh.  Inhibition of arachidonate 5-lipoxygenase triggers prostate cancer cell death through rapid activation of c-Jun N-terminal kinase. , 2003, Biochemical and biophysical research communications.

[288]  L. Marnett,et al.  The lipoxygenase gene ALOXE3 implicated in skin differentiation encodes a hydroperoxide isomerase , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[289]  R. DuBois,et al.  Leukotriene A4 signaling, inflammation, and cancer. , 2003, Journal of the National Cancer Institute.

[290]  K. Honn,et al.  Overexpression of platelet-type 12-lipoxygenase promotes tumor cell survival by enhancing alpha(v)beta(3) and alpha(v)beta(5) integrin expression. , 2003, Cancer research.

[291]  R. Newman,et al.  Subcellular Localization and Tumor-suppressive Functions of 15-Lipoxygenase 2 (15-LOX2) and Its Splice Variants* , 2003, Journal of Biological Chemistry.

[292]  D. Nie,et al.  Platelet-type 12-lipoxygenase activates NF-κB in prostate cancer cells , 2003 .

[293]  G. Melino,et al.  Mechanisms of free‐radical induction in relation to fenretinide‐induced apoptosis of neuroblastoma , 2003, Journal of cellular biochemistry.

[294]  M. Poo,et al.  Cyclic AMP/GMP-dependent modulation of Ca2+ channels sets the polarity of nerve growth-cone turning , 2003, Nature.

[295]  Santiago Canals,et al.  Nitric Oxide Triggers the Toxicity due to Glutathione Depletion in Midbrain Cultures through 12-Lipoxygenase* , 2003, Journal of Biological Chemistry.

[296]  C. Serhan,et al.  Novel Docosatrienes and 17S-Resolvins Generated from Docosahexaenoic Acid in Murine Brain, Human Blood, and Glial Cells , 2003, The Journal of Biological Chemistry.

[297]  E. Hoffman,et al.  Gene profiling in spinal cord injury shows role of cell cycle in neuronal death , 2003, Annals of neurology.

[298]  S. Lippman,et al.  Reduced 15S-lipoxygenase-2 expression in esophageal cancer specimens and cells and upregulation in vitro by the cyclooxygenase-2 inhibitor, NS398. , 2003, Neoplasia.

[299]  C. Clish,et al.  Lipoxin A4 and Aspirin-Triggered 15-epi-Lipoxin A4 Inhibit Human Neutrophil Migration: Comparisons Between Synthetic 15 Epimers in Chemotaxis and Transmigration with Microvessel Endothelial Cells and Epithelial Cells 1 , 2003, The Journal of Immunology.

[300]  D. Nie,et al.  Platelet-type 12-lipoxygenase activates NF-kappaB in prostate cancer cells. , 2003, Prostaglandins & other lipid mediators.

[301]  C. Gerth,et al.  Transient experimental anemia in cholesterol-fed rabbits induces systemic overexpression of the reticulocyte-type 15-lipoxygenase and protects from aortic lipid deposition. , 2002, Prostaglandins, leukotrienes, and essential fatty acids.

[302]  C. Funk,et al.  Cysteinyl leukotriene receptors. , 2002, Biochemical pharmacology.

[303]  T. Eling,et al.  Opposing Effects of 15-Lipoxygenase-1 and -2 Metabolites on MAPK Signaling in Prostate , 2002, The Journal of Biological Chemistry.

[304]  G. Melino,et al.  GADD153 and 12-lipoxygenase mediate fenretinide-induced apoptosis of neuroblastoma. , 2002, Cancer research.

[305]  Lei Zhao,et al.  Lipoxygenase genes and their targeted disruption. , 2002, Prostaglandins & other lipid mediators.

[306]  K. Mikule,et al.  Growth Cone Collapse Induced by Semaphorin 3A Requires 12/15-Lipoxygenase , 2002, The Journal of Neuroscience.

[307]  D. Sgroi,et al.  Genetic Regulation of Metabolic Pathways in β-Cells Disrupted by Hyperglycemia* , 2002, The Journal of Biological Chemistry.

[308]  Pavel V Baranov,et al.  Recoding: translational bifurcations in gene expression. , 2002, Gene.

[309]  D. Sgroi,et al.  Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia. , 2002, The Journal of biological chemistry.

[310]  U. Kelavkar,et al.  15-lipoxygenase-1 overexpression in prostate adenocarcinoma. , 2002, Advances in experimental medicine and biology.

[311]  U. Kelavkar,et al.  Overexpression of 15-lipoxygenase-1 in PC-3 human prostate cancer cells increases tumorigenesis. , 2001, Carcinogenesis.

[312]  Lei Zhao,et al.  12/15-Lipoxygenase Gene Disruption Attenuates Atherogenesis in LDL Receptor–Deficient Mice , 2001, Circulation.

[313]  W. Rostène,et al.  Baicalein protects cortical neurons from β-amyloid (25-35) induced toxicity , 2001 .

[314]  D. Rader,et al.  Absence of 12/15-Lipoxygenase Expression Decreases Lipid Peroxidation and Atherogenesis in Apolipoprotein E—Deficient Mice , 2001, Circulation.

[315]  D. Bostwick,et al.  Lipoxygenase‐5 is overexpressed in prostate adenocarcinoma , 2001, Cancer.

[316]  C. Funk,et al.  Role of 'platelet-type' 12-lipoxygenase in skin carcinogenesis. , 2001, Cancer letters.

[317]  R. Duvoisin,et al.  Inhibition of 15‐lipoxygenase leads to delayed organelle degradation in the reticulocyte , 2001, FEBS letters.

[318]  Rajnish A. Gupta,et al.  15S-Hydroxyeicosatetraenoic acid activates peroxisome proliferator-activated receptor gamma and inhibits proliferation in PC3 prostate carcinoma cells. , 2001, Cancer research.

[319]  W. Rostène,et al.  Baicalein protects cortical neurons from beta-amyloid (25-35) induced toxicity. , 2001, Neuroreport.

[320]  D. Steinberg,et al.  The oxidative modification hypothesis of atherogenesis: an overview. , 2000, Free radical biology & medicine.

[321]  D. Conrad,et al.  Regulation of human 12/15-lipoxygenase by Stat6-dependent transcription. , 2000, American journal of respiratory cell and molecular biology.

[322]  R. Kim,et al.  Identification of Amino Acid Determinants of the Positional Specificity of Mouse 8S-Lipoxygenase and Human 15S-Lipoxygenase-2* , 2000, The Journal of Biological Chemistry.

[323]  K. Mikule,et al.  Thrombin causes pseudopod detachment via a pathway involving cytosolic phospholipase A2 and 12/15-lipoxygenase products. , 2000, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[324]  R. Fletterick,et al.  Shape and Specificity in Mammalian 15-Lipoxygenase Active Site , 1999, The Journal of Biological Chemistry.

[325]  K. Mikule,et al.  Thrombin-Induced Growth Cone Collapse: Involvement of Phospholipase A2 and Eicosanoid Generation , 1999, The Journal of Neuroscience.

[326]  Y. Kaneda,et al.  Transfection of rat kidney with human 15-lipoxygenase suppresses inflammation and preserves function in experimental glomerulonephritis. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[327]  L. Horrocks,et al.  Health benefits of docosahexaenoic acid (DHA) , 1999, Pharmacological research.

[328]  T. Willson,et al.  Interleukin-4-dependent production of PPAR-γ ligands in macrophages by 12/15-lipoxygenase , 1999, Nature.

[329]  A. Brash,et al.  15-lipoxygenase-2 (15-LOX-2) is expressed in benign prostatic epithelium and reduced in prostate adenocarcinoma. , 1999, The American journal of pathology.

[330]  C. Funk,et al.  Basal transepidermal water loss is increased in platelet-type 12-lipoxygenase deficient mice. , 1999, The Journal of investigative dermatology.

[331]  F. Marks,et al.  cDNA cloning, genomic structure, and chromosomal localization of a novel murine epidermis-type lipoxygenase. , 1999, Genomics.

[332]  D. Rader,et al.  Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice. , 1999, The Journal of clinical investigation.

[333]  D. Bleich,et al.  Resistance to type 1 diabetes induction in 12-lipoxygenase knockout mice. , 1999, The Journal of clinical investigation.

[334]  M. Paparella,et al.  Pneumococcus activation of the 5-lipoxygenase pathway and production of glycoproteins in the middle ear of rats. , 1999, The Journal of infectious diseases.

[335]  J. Mulshine,et al.  Relationship of arachidonic acid metabolizing enzyme expression in epithelial cancer cell lines to the growth effect of selective biochemical inhibitors. , 1999, Cancer research.

[336]  P. Steinert,et al.  Bricks and mortar of the epidermal barrier , 1999, Experimental & Molecular Medicine.

[337]  B. Thiele,et al.  Cloning of the mouse phospholipid hydroperoxide glutathione peroxidase gene 1 , 1999, FEBS letters.

[338]  H. Kuhn,et al.  Inverse regulation of lipid‐peroxidizing and hydroperoxyl lipid‐reducing enzymes by interleukins 4 and 13 , 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[339]  T. Willson,et al.  Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase. , 1999, Nature.

[340]  T. Murohara,et al.  Platelet-derived 12-hydroxyeicosatetraenoic acid plays an important role in mediating canine coronary thrombosis by regulating platelet glycoprotein IIb/IIIa activation. , 1998, Circulation.

[341]  P. Patel,et al.  Human 12(R)-Lipoxygenase and the Mouse Ortholog , 1998, The Journal of Biological Chemistry.

[342]  J. Falck,et al.  Identification of the 11,14,15- and 11,12,15-Trihydroxyeicosatrienoic Acids as Endothelium-derived Relaxing Factors of Rabbit Aorta* , 1998, The Journal of Biological Chemistry.

[343]  C. Myers,et al.  Inhibition of arachidonate 5-lipoxygenase triggers massive apoptosis in human prostate cancer cells. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[344]  J. Ihle,et al.  Interleukin-4 and -13 induce upregulation of the murine macrophage 12/15-lipoxygenase activity: evidence for the involvement of transcription factor STAT6. , 1998, Blood.

[345]  R. Duvoisin,et al.  A function for lipoxygenase in programmed organelle degradation , 1998, Nature.

[346]  D. Grignon,et al.  Platelet-type 12-lipoxygenase in a human prostate carcinoma stimulates angiogenesis and tumor growth. , 1998, Cancer research.

[347]  H. Kühn,et al.  The Rabbit 15-Lipoxygenase Preferentially Oxygenates LDL Cholesterol Esters, and This Reaction Does Not Require Vitamin E* , 1998, The Journal of Biological Chemistry.

[348]  T. Wynn,et al.  Mice deficient for 5-lipoxygenase, but not leukocyte-type 12-lipoxygenase, display altered immune responses during infection with Schistosoma mansoni. , 1998, Prostaglandins & other lipid mediators.

[349]  J. Vanderhoek,et al.  Mono (S) hydroxy fatty acids: novel ligands for cytosolic actin. , 1998, Journal of lipid research.

[350]  M. Yacoub,et al.  Differential leukotriene constrictor responses in human atherosclerotic coronary arteries. , 1998, Circulation.

[351]  R. Kim,et al.  A 12R-lipoxygenase in human skin: mechanistic evidence, molecular cloning, and expression. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[352]  B. Thiele,et al.  Simultaneous expression of leukocyte-type 12-lipoxygenase and reticulocyte-type 15-lipoxygenase in rabbits. , 1998, Journal of molecular biology.

[353]  C. Funk,et al.  Increased platelet sensitivity to ADP in mice lacking platelet-type 12-lipoxygenase. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[354]  A. Nasjletti,et al.  Arthur C. Corcoran Memorial Lecture. The role of eicosanoids in angiotensin-dependent hypertension. , 1998, Hypertension.

[355]  D. Bleich,et al.  The role of 12-lipoxygenase in pancreatic -cells (Review). , 1998, International journal of molecular medicine.

[356]  K. Schnurr,et al.  Membrane translocation of 15-lipoxygenase in hematopoietic cells is calcium-dependent and activates the oxygenase activity of the enzyme. , 1998, Blood.

[357]  Robert Fletterick,et al.  The structure of mammalian 15-lipoxygenase reveals similarity to the lipases and the determinants of substrate specificity , 1997, Nature Structural Biology.

[358]  F. Sarkar,et al.  Production of 13-hydroxyoctadecadienoic acid (13-HODE) by prostate tumors and cell lines. , 1997, Biochemical and biophysical research communications.

[359]  R. Kim,et al.  Molecular Cloning and Functional Expression of a Phorbol Ester-inducible 8S-Lipoxygenase from Mouse Skin* , 1997, The Journal of Biological Chemistry.

[360]  A. Brash,et al.  Discovery of a second 15S-lipoxygenase in humans. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[361]  J. Gosselin,et al.  Epstein-Barr virus modulates 5-lipoxygenase product synthesis in human peripheral blood mononuclear cells. , 1997, Blood.

[362]  R. D. Dyer,et al.  Attenuation of diet‐induced atherosclerosis in rabbits with a highly selective 15‐lipoxygenase inhibitor lacking significant antioxidant properties , 1997, British journal of pharmacology.

[363]  D. Heydeck,et al.  In vivo action of 15-lipoxygenase in early stages of human atherogenesis. , 1997, The Journal of clinical investigation.

[364]  R. Kuban,et al.  Phenylalanine 353 is a primary determinant for the positional specificity of mammalian 15-lipoxygenases. , 1996, Journal of molecular biology.

[365]  J. Cornhill,et al.  Macrophage-mediated 15-lipoxygenase expression protects against atherosclerosis development. , 1996, The Journal of clinical investigation.

[366]  C. Funk,et al.  Disruption of 12/15-Lipoxygenase Expression in Peritoneal Macrophages , 1996, The Journal of Biological Chemistry.

[367]  H. Kühn,et al.  Biosynthesis, metabolization and biological importance of the primary 15-lipoxygenase metabolites 15-hydro(pero)XY-5Z,8Z,11Z,13E-eicosatetraenoic acid and 13-hydro(pero)XY-9Z,11E-octadecadienoic acid. , 1996, Progress in lipid research.

[368]  M. Baudry,et al.  Involvement of the 12-lipoxygenase pathway of arachidonic acid metabolism in homosynaptic long-term depression of the rat hippocampus , 1996, Brain Research.

[369]  J. Falgueyret,et al.  Characterization of the arachidonate and ATP binding sites of human 5-lipoxygenase using photoaffinity labeling and enzyme immobilization. , 1995, Biochemistry.

[370]  V. A. Folcik,et al.  Lipoxygenase contributes to the oxidation of lipids in human atherosclerotic plaques. , 1995, The Journal of clinical investigation.

[371]  S. Wohlfeil,et al.  Involvement of 15-lipoxygenase in early stages of atherogenesis , 1994, The Journal of experimental medicine.

[372]  N. Copeland,et al.  cDNA cloning, expression, mutagenesis of C-terminal isoleucine, genomic structure, and chromosomal localizations of murine 12-lipoxygenases. , 1994, The Journal of biological chemistry.

[373]  S. Yamamoto,et al.  Arachidonate 12-lipoxygenase of rat pineal glands: catalytic properties and primary structure deduced from its cDNA. , 1994, Biochimica et biophysica acta.

[374]  H. Chan,et al.  Overexpression, purification and characterization of human recombinant 15-lipoxygenase. , 1993, Biochimica et biophysica acta.

[375]  J. Rossi,et al.  Elevated glucose and angiotensin II increase 12-lipoxygenase activity and expression in porcine aortic smooth muscle cells. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[376]  T. Watanabe,et al.  Rat 12-lipoxygenase: mutations of amino acids implicated in the positional specificity of 15- and 12-lipoxygenases. , 1993, Biochemical and biophysical research communications.

[377]  D. Dewitt,et al.  Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal anti-inflammatory drugs. , 1993, The Journal of biological chemistry.

[378]  T. Watanabe,et al.  Molecular cloning of a 12-lipoxygenase cDNA from rat brain. , 1993, European journal of biochemistry.

[379]  M. Rosolowsky,et al.  Role of PGI2 and epoxyeicosatrienoic acids in relaxation of bovine coronary arteries to arachidonic acid. , 1993, The American journal of physiology.

[380]  W. Campbell,et al.  Arachidonic acid- and acetylcholine-induced relaxations of rabbit aorta. , 1992, Hypertension.

[381]  W. Finkbeiner,et al.  Cloning of human airway 15-lipoxygenase: identity to the reticulocyte enzyme and expression in epithelium. , 1992, The American journal of physiology.

[382]  E. Sigal,et al.  Cloning and expression of an airway epithelial 12-lipoxygenase. , 1992, The American journal of physiology.

[383]  H. Kuhn,et al.  Specific inflammatory cytokines regulate the expression of human monocyte 15-lipoxygenase. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[384]  C. Craik,et al.  A primary determinant for lipoxygenase positional specificity , 1991, Nature.

[385]  D. Piomelli.  Metabolism of arachidonic acid in nervous system of marine mollusk Aplysia californica. , 1991, The American journal of physiology.

[386]  R. Wiesner,et al.  The oxygenation of cholesterol esters by the reticulocyte lipoxygenase , 1991, FEBS letters.

[387]  R. Dixon,et al.  Expression of cloned human 15-lipoxygenase in eukaryotic and prokaryotic systems. , 1991, Advances in prostaglandin, thromboxane, and leukotriene research.

[388]  M. Nishiyama,et al.  Localization of arachidonate 12-lipoxygenase in canine brain tissues. , 1991, Journal of neurochemistry.

[389]  D. Steinberg,et al.  Role of oxidised low density lipoprotein in atherogenesis. , 1993, British heart journal.

[390]  A. Brash,et al.  Oxygenation of biological membranes by the pure reticulocyte lipoxygenase. , 1990, The Journal of biological chemistry.

[391]  G. FitzGerald,et al.  Molecular cloning, primary structure, and expression of the human platelet/erythroleukemia cell 12-lipoxygenase. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[392]  S. Yamamoto,et al.  Cloning and sequence analysis of the cDNA for arachidonate 12-lipoxygenase of porcine leukocytes. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[393]  A. Brash,et al.  Occurrence of lipoxygenase products in membranes of rabbit reticulocytes. Evidence for a role of the reticulocyte lipoxygenase in the maturation of red cells. , 1990, The Journal of biological chemistry.

[394]  S Hoshiko,et al.  Characterization of the human 5-lipoxygenase gene. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[395]  M. Moskowitz,et al.  A flavonoid inhibitor of 5-lipoxygenase inhibits leukotriene production following ischemia in gerbil brain. , 1989, Stroke.

[396]  M. Moskowitz,et al.  Blood components contribute to rise in gerbil brain levels of leukotriene-like immunoreactivity after ischemia and reperfusion. , 1988, Stroke.

[397]  C. Craik,et al.  Arachidonate 15-lipoxygenase from human eosinophil-enriched leukocytes: partial purification and properties. , 1988, Biochemical and biophysical research communications.

[398]  R. de Caterina,et al.  Leukotriene B4 production in human atherosclerotic plaques. , 1988, Biomedica biochimica acta.

[399]  J. Rokach,et al.  Formation of lipoxin B by the pure reticulocyte lipoxygenase via sequential oxygenation of the substrate. , 1987, European journal of biochemistry.

[400]  E. Shapiro,et al.  Metabolites of arachidonic acid in the nervous system of Aplysia: possible mediators of synaptic modulation , 1987, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[401]  S. Dahlén,et al.  Leukotrienes and lipoxins: structures, biosynthesis, and biological effects. , 1987, Science.

[402]  E. Kandel,et al.  Lipoxygenase metabolites of arachidonic acid as second messengers for presynaptic inhibition of Aplysia sensory cells , 1987, Nature.

[403]  S. Rapoport,et al.  Enzymology and physiology of reticulocyte lipoxygenase: comparison with other lipoxygenases. , 2006, Advances in enzymology and related areas of molecular biology.

[404]  S. Rapoport,et al.  The maturational breakdown of mitochondria in reticulocytes. , 1986, Biochimica et biophysica acta.

[405]  J. Salmon,et al.  Supplementation of the diet with eicosapentaenoic acid: a possible approach to the treatment of thrombosis and inflammation , 1985, Proceedings of the Nutrition Society.

[406]  S. Rapoport,et al.  Proteolysis during in vitro-maturation of rabbit reticulocytes. , 1985, Biomedica biochimica acta.

[407]  J. Shelhamer,et al.  Human respiratory mucus. , 1986, The Journal of allergy and clinical immunology.

[408]  T. Steck,et al.  Maturation of the reticulocyte in vitro. , 1984, Journal of cell science.

[409]  M. Moskowitz,et al.  Synthesis of compounds with properties of leukotrienes C4 and D4 in gerbil brains after ischemia and reperfusion. , 1984, Science.

[410]  R. Fishman,et al.  Induction of brain edema following intracerebral injection of arachidonic acid , 1983, Annals of neurology.

[411]  S. Rapoport,et al.  In vitro maturation of rabbit reticulocytes. III. Response of lipoxygenase. , 1983, Biomedica biochimica acta.

[412]  P. Piper,et al.  THE EFFECT OF LEUKOTRIENE C4 ON MUCIN RELEASE INTO THE CAT TRACHEA in vivo AND in vitro , 1982, British journal of pharmacology.

[413]  J. Palmblad,et al.  Leukotriene B4 is a potent and stereospecific stimulator of neutrophil chemotaxis and adherence. , 1981, Blood.

[414]  S. Dahlén,et al.  Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[415]  S. Rapoport,et al.  Lipoxygenase from rabbit reticulocytes. , 1981, Methods in enzymology.

[416]  Bengt Samuelsson,et al.  Leukotrienes are potent constrictors of human bronchi , 1980, Nature.

[417]  C. Tannert,et al.  The Lipoxygenase of Reticulocytes , 1979 .

[418]  C. Tannert,et al.  The lipoxygenase of reticulocytes. Purification, characterization and biological dynamics of the lipoxygenase; its identity with the respiratory inhibitors of the reticulocyte. , 1979, European journal of biochemistry.

[419]  P. Chan,et al.  Brain edema: induction in cortical slices by polyunsaturated fatty acids. , 1978, Science.

[420]  S. Rapoport,et al.  Degradation of mitochondria by cytosolic factors in reticulocytes. , 1977, Acta biologica et medica Germanica.

[421]  S. Rapoport,et al.  A lipoxygenase in rabbit reticulocytes which attacks phospholipids and intact mitochondria , 1975, FEBS letters.

[422]  M. Hamberg,et al.  Prostaglandin endoperoxides. Novel transformations of arachidonic acid in human platelets. , 1974, Proceedings of the National Academy of Sciences of the United States of America.

[423]  N. Bazan,et al.  Effects of ischemia and electroconvulsive shock on free fatty acid pool in the brain. , 1970, Biochimica et biophysica acta.

[424]  G. Kent,et al.  Autophagic vacuoles in human red cells. , 1966, The American journal of pathology.