Designs for Mixture Experiments Involving Process Variables

Published procedures for mixture experimentation in the presence of process variables arc reviewed. Procedures which inscribe figures in the mixture space result in lower numbers of experiments but are limited because they do not permit full exploration of the mixture space. In this paper, alternative procedures which minimize the loss of the mixture space are presented. Eight cases representing all combinations of the following are considered: three and four mixture variables, with and without a center point of interest in the mixture space, and with and without constraints on compositions. Solutions are lists of coordinates of the vertices of the cuboidal regions inscribed in the mixture space. Transformations which facilitate linking the mixture space with the factor space of the independent variables are also presented.

[1]  N. G. Becker Regression Problems When the Predictor Variables are Proportions , 1969 .

[2]  J. W. Gorman Fitting Equations to Mixture Data with Restraints on Compositions , 1970 .

[3]  John A. Cornell,et al.  Experiments with Mixtures: An Update and Bibliography , 1979 .

[4]  Ronald D. Snee Techniques for the Analysis of Mixture Data , 1973 .

[5]  Raymond H. Myers,et al.  Response Surface Designs for Experiments with Mixtures , 1968 .

[6]  H. Scheffé The Simplex‐Centroid Design for Experiments with Mixtures , 1963 .

[7]  H. Scheffé Experiments with Mixtures , 1958 .

[8]  John A. Cornell,et al.  Process Variables in the Mixture Problem for Categorized Components , 1971 .

[9]  Norman R. Draper,et al.  Mixture Designs for Three Factors , 1965 .

[10]  P. J. Claringbold USE OF THE SIMPLEX DESIGN IN THE STUDY OF JOINT ACTION OF RELATED HORMONES , 1955 .

[11]  John W. Gorman,et al.  Simplex Lattice Designs for Multicomponent Systems , 1962 .

[12]  David R. Cox,et al.  A note on polynomial response functions for mixtures , 1971 .

[13]  N. G. Becker Models for the Response of a Mixture , 1968 .

[14]  A. K. Nigam,et al.  Block Designs for Mixture Experiments , 1970 .

[15]  John A. Cornell,et al.  The Mixture Problem for Categorized Components , 1970 .

[16]  N. Draper,et al.  A Mixtures Model with Inverse Terms , 1977 .

[17]  John A. Cornell,et al.  EXPERIMENTS WITH MIXTURES: A REVIEW , 1973 .

[18]  M. N. Das,et al.  Design and Analysis of Experiments with Mixtures , 1968 .