Management of cervicofacial nontuberculous lymphadenitis in children

Purpose of reviewTo review the body of literature on the treatment options for nontuberculous cervicofacial lymphadenitis in children, focusing on the most recent reports describing outcomes utilizing either observation alone, medical therapy or various forms of surgical intervention. Recent findingsLarge studies have defined the time course of the disease and the safety and efficacy in treating nontuberculosis cervicofacial lymphadenitis with a wait-and-see approach. SummaryNontuberculosis cervicofacial lymphadenitis is a disease with several stages that provides for various treatment options. All treatment regimens – wait-and-see approach, medical therapy, and surgical excision – have their risks and benefits. The current body of literature allows the otolaryngologist an assortment of treatment choices that permits him to tailor the treatment with an individualized approach for each family's preferences.

[1]  J. Cherry,et al.  Feigin and Cherry's textbook of pediatric infectious diseases , 2013 .

[2]  R. Wallace,,et al.  Antimicrobial Susceptibility Testing, Drug Resistance Mechanisms, and Therapy of Infections with Nontuberculous Mycobacteria , 2012, Clinical Microbiology Reviews.

[3]  E. Harley,et al.  Nontuberculous mycobacterial cervicofacial lymphadenitis--a review and proposed classification system. , 2011, International journal of pediatric otorhinolaryngology.

[4]  Jerome A Lindeboom,et al.  Conservative wait-and-see therapy versus antibiotic treatment for nontuberculous mycobacterial cervicofacial lymphadenitis in children. , 2011, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[5]  G. Eliopoulos,et al.  The Sanford guide to antimicrobial therapy , 2010 .

[6]  J. Buwalda,et al.  Treatment of non‐tuberculous mycobacterial cervicofacial lymphadenitis in children: critical appraisal of the literature , 2008, Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery.

[7]  Z. Samra,et al.  Management of Nontuberculous Mycobacteria-Induced Cervical Lymphadenitis With Observation Alone , 2008, The Pediatric infectious disease journal.

[8]  H. Kubba,et al.  Atypical mycobacterial infection of the head and neck in children: A 5-year retrospective review , 2008, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[9]  R. Wallace Mycobacterium Species Non-tuberculosis , 2008 .

[10]  J. Prins,et al.  Surgical excision versus antibiotic treatment for nontuberculous mycobacterial cervicofacial lymphadenitis in children: a multicenter, randomized, controlled trial. , 2007, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[11]  H. Jafri,et al.  Antibiotic Therapy for Nontuberculous Mycobacterial Cervicofacial Lymphadenitis , 2005, The Laryngoscope.

[12]  E. Claas,et al.  Mycobacterium haemophilum and Lymphadenitis in Children , 2005, Emerging infectious diseases.

[13]  S. Pransky,et al.  Nontuberculous mycobacterial infections of the head and neck. , 2003, Pediatric clinics of North America.

[14]  E. Wald,et al.  Management of nontuberculous mycobacterial cervical lymphadenitis. , 2003, Archives of otolaryngology--head & neck surgery.

[15]  K. Higgins,et al.  Nontuberculous Mycobacterial Cervical Adenitis: A Ten‐Year Retrospective Review , 2003, The Laryngoscope.

[16]  B. Tapiéro,et al.  Nontuberculous Mycobacterial Adenitis of the Head and Neck in Children: Experience From a Tertiary Care Pediatric Center , 2001, The Laryngoscope.

[17]  J. Graybill,et al.  Disseminated Mycobacterium simiae infection in patients with AIDS. , 2000, The Journal of infection.

[18]  J. Starke Management of nontuberculous mycobacterial cervical adenitis. , 2000, The Pediatric infectious disease journal.

[19]  J. de Lange,et al.  Clarithromycin as a single-modality treatment in mycobacterial avium-intracellular infections. , 1999, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

[20]  C. Robson,et al.  Lymphadenitis due to nontuberculous mycobacteria in children: presentation and response to therapy. , 1999, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[21]  R. Wetmore,et al.  Nontuberculous Mycobacterial Cervical Adenitis , 1997, Clinical pediatrics.

[22]  D. Nadal,et al.  Treatment of nontuberculous mycobacterial lymphadenitis with clarithromycin plus rifabutin. , 1996, The Journal of pediatrics.

[23]  T. Kennedy Curettage of nontuberculous mycobacterial cervical lymphadenitis. , 1992, Archives of otolaryngology--head & neck surgery.

[24]  N. R. Olson Nontuberculous mycobacterial infections of the face and neck — Practical considerations , 1981, The Laryngoscope.

[25]  G. Mccracken,et al.  Management of atypical mycobacterial lymphadenitis in childhood: a review based on 380 cases. , 1979, The Journal of pediatrics.