FTY720 induces ferroptosis and autophagy via PP2A/AMPK pathway in multiple myeloma cells.
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Y. Zhong | Zhuogang Liu | Huihan Wang | F. Tian | Wei Yang | A. Liao | Huanxin Ma
[1] Z. Xia,et al. Diabetes aggravates myocardial ischaemia reperfusion injury via activating Nox2‐related programmed cell death in an AMPK‐dependent manner , 2020, Journal of cellular and molecular medicine.
[2] Stephen A. Sastra,et al. Cysteine depletion induces pancreatic tumor ferroptosis in mice , 2020, Science.
[3] Jitendra Kumar Meena,et al. Energy stress-mediated AMPK activation inhibits ferroptosis , 2020, Nature Cell Biology.
[4] D. Krysko,et al. Ferroptosis at the crossroads of cancer-acquired drug resistance and immune evasion , 2019, Nature Reviews Cancer.
[5] X. Ao,et al. Molecular mechanisms of ferroptosis and its role in cancer therapy , 2019, Journal of cellular and molecular medicine.
[6] T. Vanden Berghe,et al. Targeting Ferroptosis to Iron Out Cancer. , 2019, Cancer cell.
[7] A. Chinnaiyan,et al. CD8+ T cells regulate tumor ferroptosis during cancer immunotherapy , 2019, Nature.
[8] W. Fan,et al. DHA inhibits proliferation and induces ferroptosis of leukemia cells through autophagy dependent degradation of ferritin , 2019, Free radical biology & medicine.
[9] Wei Li,et al. BAP1 links metabolic regulation of ferroptosis to tumor suppression , 2018, Nature Cell Biology.
[10] D. Klionsky,et al. AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc – Activity , 2018, Current Biology.
[11] G. J. Yoshida. Comment on “Targeting AMPK, mTOR and β-Catenin by Combined Metformin and Aspirin Therapy in HCC: An Appraisal in Egyptian HCC Patients” , 2018, Molecular Diagnosis & Therapy.
[12] R. Shaw,et al. AMPK: guardian of metabolism and mitochondrial homeostasis , 2017, Nature Reviews Molecular Cell Biology.
[13] B. Stockwell,et al. Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease , 2017, Cell.
[14] C. Chiu,et al. FTY720 Induces Autophagy-Associated Apoptosis in Human Oral Squamous Carcinoma Cells, in Part, through a Reactive Oxygen Species/Mcl-1-Dependent Mechanism , 2017, Scientific Reports.
[15] G. J. Yoshida. Therapeutic strategies of drug repositioning targeting autophagy to induce cancer cell death: from pathophysiology to treatment , 2017, Journal of Hematology & Oncology.
[16] Q. Pan,et al. Ferroptosis is an autophagic cell death process , 2016, Cell Research.
[17] M. Lotze,et al. Autophagy promotes ferroptosis by degradation of ferritin , 2016, Autophagy.
[18] W. Gu,et al. Ferroptosis as a p53-mediated activity during tumour suppression , 2015, Nature.
[19] H. Tseng,et al. Involvement of vacuolar H+‐ATPase in killing of human melanoma cells by the sphingosine kinase analogue FTY720 , 2015, Pigment cell & melanoma research.
[20] A. Walch,et al. Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice , 2014, Nature Cell Biology.
[21] Matthew E. Welsch,et al. Regulation of Ferroptotic Cancer Cell Death by GPX4 , 2014, Cell.
[22] Han-dong Wang,et al. FTY720 for cancer therapy (Review). , 2013, Oncology reports.
[23] D. Perrotti,et al. Protein phosphatase 2A: a target for anticancer therapy. , 2013, The Lancet. Oncology.
[24] M. R. Lamprecht,et al. Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death , 2012, Cell.
[25] Zhuogang Liu,et al. Autophagy induced by FTY720 promotes apoptosis in U266 cells. , 2012, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[26] J. Byrd,et al. FTY720 increases CD74 expression and sensitizes mantle cell lymphoma cells to milatuzumab-mediated cell death. , 2011, Blood.
[27] C. Wallington-Beddoe,et al. FTY720 produces caspase-independent cell death of acute lymphoblastic leukemia cells , 2011, Autophagy.
[28] Nicholas H Oberlies,et al. Fingolimod (FTY720): a recently approved multiple sclerosis drug based on a fungal secondary metabolite. , 2011, Journal of natural products.
[29] Y. Qi,et al. FTY720 induces necrotic cell death and autophagy in ovarian cancer cells: A protective role of autophagy , 2010, Autophagy.
[30] V. Janssens,et al. PP2A holoenzyme assembly: in cauda venenum (the sting is in the tail). , 2008, Trends in biochemical sciences.
[31] Guido Kroemer,et al. Autophagy in the Pathogenesis of Disease , 2008, Cell.
[32] M. Ikekita,et al. A novel immunosuppressive agent FTY720 induced Akt dephosphorylation in leukemia cells , 2003, British journal of pharmacology.
[33] A. Nairn,et al. Identification of calmodulin-dependent protein kinase III and its major Mr 100,000 substrate in mammalian tissues. , 1985, Proceedings of the National Academy of Sciences of the United States of America.