Adiponectin negatively regulates pigmentation, Wnt/β-catenin and HGF/c-Met signalling within human scalp hair follicles ex vivo

[1]  A. Schulte-Mecklenbeck,et al.  Resident human dermal γδT-cells operate as stress-sentinels: Lessons from the hair follicle. , 2021, Journal of autoimmunity.

[2]  John P. Cole,et al.  AIRMESS – Academy of International Regenerative Medicine & Surgery Societies: recommendations in the use of platelet-rich plasma (PRP), autologous stem cell-based therapy (ASC-BT) in androgenetic alopecia and wound healing , 2021, Expert opinion on biological therapy.

[3]  R. Paus,et al.  Dermal adipose tissue secretes HGF to promote human hair growth and pigmentation. , 2021, The Journal of investigative dermatology.

[4]  A. Pawlik,et al.  Role of Adiponectin in the Pathogenesis of Rheumatoid Arthritis , 2020, International journal of molecular sciences.

[5]  P. Park,et al.  Recent insights on modulation of inflammasomes by adipokines: a critical event for the pathogenesis of obesity and metabolism-associated diseases , 2020, Archives of Pharmacal Research.

[6]  D. Tobin,et al.  The biology of human hair greying , 2020, Biological reviews of the Cambridge Philosophical Society.

[7]  A. Schulte-Mecklenbeck,et al.  Pro-inflammatory Vδ1+T-cells infiltrates are present in and around the hair bulbs of non-lesional and lesional alopecia areata hair follicles. , 2020, Journal of dermatological science.

[8]  Thi Mong Diep Nguyen.  Adiponectin: Role in Physiology and Pathophysiology , 2020, International journal of preventive medicine.

[9]  J. E. Lee,et al.  Adiponectin: The Potential Regulator and Therapeutic Target of Obesity and Alzheimer’s Disease , 2020, International journal of molecular sciences.

[10]  J. Szepietowski,et al.  Adipokines as Biomarkers of Atopic Dermatitis in Adults , 2020, Journal of clinical medicine.

[11]  M. Dalamaga,et al.  Deciphering the Association Between Psoriasis and Obesity: Current Evidence and Treatment Considerations , 2020, Current Obesity Reports.

[12]  Kyung-Eun Lee,et al.  Caviar Extract and Its Constituent DHA Inhibits UVB-Irradiated Skin Aging by Inducing Adiponectin Production , 2020, International journal of molecular sciences.

[13]  C. Collet,et al.  Mutltifaceted biological roles of adiponectin. , 2020, Annales de biologie clinique.

[14]  R. Paus,et al.  Deciphering the molecular morphology of the human hair cycle: Wnt signalling during the telogen–anagen transformation , 2020, The British journal of dermatology.

[15]  P. Gentile,et al.  Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil®, Finasteride®, and Adult Stem Cell-Based Therapy , 2020, International journal of molecular sciences.

[16]  P. Gentile,et al.  Autologous activated platelet-rich plasma (AA-PRP) and non-activated (A-PRP) in hair growth: a retrospective, blinded, randomized evaluation in androgenetic alopecia , 2020, Expert opinion on biological therapy.

[17]  K. Kim,et al.  Multifaceted Physiological Roles of Adiponectin in Inflammation and Diseases , 2020, International journal of molecular sciences.

[18]  P. Gentile,et al.  Autologous Micrografts from Scalp Tissue: Trichoscopic and Long-Term Clinical Evaluation in Male and Female Androgenetic Alopecia , 2020, BioMed research international.

[19]  P. Gentile,et al.  Impact of the Different Preparation Methods to Obtain Autologous Non-Activated Platelet-Rich Plasma (A-PRP) and Activated Platelet-Rich Plasma (AA-PRP) in Plastic Surgery: Wound Healing and Hair Regrowth Evaluation , 2020, International journal of molecular sciences.

[20]  P. Scherer,et al.  Dermal adipose tissue has high plasticity and undergoes reversible dedifferentiation in mice. , 2019, The Journal of clinical investigation.

[21]  P. Gentile.  Autologous Cellular Method Using Micrografts of Human Adipose Tissue Derived Follicle Stem Cells in Androgenic Alopecia , 2019, International journal of molecular sciences.

[22]  R. Paus,et al.  Human perifollicular macrophages undergo apoptosis, express Wnt ligands and switch their polarisation during catagen. , 2019, The Journal of investigative dermatology.

[23]  Pietro Gentile,et al.  Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth-Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development , 2019, Cells.

[24]  P. Gentile,et al.  Platelet-Rich Plasma and Micrografts Enriched with Autologous Human Follicle Mesenchymal Stem Cells Improve Hair Re-Growth in Androgenetic Alopecia. Biomolecular Pathway Analysis and Clinical Evaluation , 2019, Biomedicines.

[25]  R. Paus,et al.  Hair growth control by innate immunocytes: Perifollicular macrophages revisited , 2019, Experimental dermatology.

[26]  P. Scherer,et al.  Metabolic Messengers: adiponectin , 2019, Nature Metabolism.

[27]  M. Czyz,et al.  HGF/c-MET Signaling in Melanocytes and Melanoma , 2018, International journal of molecular sciences.

[28]  D. Tobin.  Early evidence for opposing effects of full versus fragmented adiponectin on melanogenesis in human epidermal melanocytes , 2018, The British journal of dermatology.

[29]  J. Varga,et al.  An orally-active adiponectin receptor agonist mitigates cutaneous fibrosis, inflammation and microvascular pathology in a murine model of systemic sclerosis , 2018, Scientific Reports.

[30]  S. Lee,et al.  Globular adiponectin acts as a melanogenic signal in human epidermal melanocytes , 2018, The British journal of dermatology.

[31]  X. Lim,et al.  Identifying novel strategies for treating human hair loss disorders: Cyclosporine A suppresses the Wnt inhibitor, SFRP1, in the dermal papilla of human scalp hair follicles , 2018, PLoS biology.

[32]  P. Gentile,et al.  Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia. , 2018, Journal of visualized experiments : JoVE.

[33]  B. Seliger,et al.  Adiponectin and Its Receptors Are Differentially Expressed in Human Tissues and Cell Lines of Distinct Origin , 2017, Obesity Facts.

[34]  R. Paus,et al.  Characterisation of cell cycle arrest and terminal differentiation in a maximally proliferative human epithelial tissue: Lessons from the human hair follicle matrix. , 2017, European journal of cell biology.

[35]  W. Tourtellotte,et al.  Adiponectin is an endogenous anti-fibrotic mediator and therapeutic target , 2017, Scientific Reports.

[36]  Han Liu,et al.  Adiponectin Is Involved in Connective Tissue Growth Factor-Induced Proliferation, Migration and Overproduction of the Extracellular Matrix in Keloid Fibroblasts , 2017, International journal of molecular sciences.

[37]  A. Mortazavi,et al.  Regeneration of fat cells from myofibroblasts during wound healing , 2017, Science.

[38]  John P. Cole,et al.  Evaluation of Not-Activated and Activated PRP in Hair Loss Treatment: Role of Growth Factor and Cytokine Concentrations Obtained by Different Collection Systems , 2017, International journal of molecular sciences.

[39]  Jeung-Hoon Lee,et al.  Adiponectin Signaling Regulates Lipid Production in Human Sebocytes , 2017, PloS one.

[40]  Y. Hsu,et al.  Hair follicles’ transit-amplifying cells govern concurrent dermal adipocyte production through Sonic Hedgehog , 2016, Genes & development.

[41]  M. Cree‐Green,et al.  Ethnic and Sex Differences in Adiponectin: From Childhood to Adulthood. , 2016, The Journal of clinical endocrinology and metabolism.

[42]  Mi-Kyung Lee,et al.  Adiponectin corrects premature cellular senescence and normalizes antimicrobial peptide levels in senescent keratinocytes. , 2016, Biochemical and biophysical research communications.

[43]  Mi-Kyung Lee,et al.  Adiponectin Suppresses UVB-Induced Premature Senescence and hBD2 Overexpression in Human Keratinocytes , 2016, PloS one.

[44]  Chien-Liang Fang,et al.  Dermal Lipogenesis Inhibits Adiponectin Production in Human Dermal Fibroblasts while Exogenous Adiponectin Administration Prevents against UVA-Induced Dermal Matrix Degradation in Human Skin , 2016, International journal of molecular sciences.

[45]  P. Scherer,et al.  Adiponectin, the past two decades. , 2016, Journal of molecular cell biology.

[46]  C. Zouboulis,et al.  Sebocytes differentially express and secrete adipokines , 2016, Experimental dermatology.

[47]  J. Varga,et al.  Adiponectin inhibits Wnt co-receptor, Lrp6, phosphorylation and β-catenin signaling. , 2016, Biochemical and biophysical research communications.

[48]  R. Paus,et al.  Human hair follicle organ culture: theory, application and perspectives , 2015, Experimental dermatology.

[49]  B. Andersen,et al.  Resting no more: re‐defining telogen, the maintenance stage of the hair growth cycle , 2015, Biological reviews of the Cambridge Philosophical Society.

[50]  P. Gentile,et al.  The Effect of Platelet‐Rich Plasma in Hair Regrowth: A Randomized Placebo‐Controlled Trial , 2015, Stem cells translational medicine.

[51]  R. Paus,et al.  Re-Evaluating Cyclosporine A as a Hair Growth-Promoting Agent in Human Scalp Hair Follicles. , 2015, The Journal of investigative dermatology.

[52]  T. Kadowaki,et al.  Adiponectin regulates psoriasiform skin inflammation by suppressing IL-17 production from γδ-T cells , 2015, Nature Communications.

[53]  D. Tobin,et al.  The peripheral clock regulates human pigmentation. , 2015, The Journal of investigative dermatology.

[54]  Y. Tsai,et al.  Leptin of dermal adipose tissue is differentially expressed during the hair cycle and contributes to adipocyte‐mediated growth inhibition of anagen‐phase vibrissa hair , 2015, Experimental dermatology.

[55]  P. Gentile,et al.  The Effect of Autologous Activated Platelet Rich Plasma (AA-PRP) Injection on Pattern Hair Loss: Clinical and Histomorphometric Evaluation , 2014, BioMed research international.

[56]  R. Paus,et al.  Human epithelial hair follicle stem cells and their progeny: Current state of knowledge, the widening gap in translational research and future challenges , 2014, BioEssays : news and reviews in molecular, cellular and developmental biology.

[57]  S. Inui,et al.  Hair cycle control by leptin as a new anagen inducer , 2014, Experimental dermatology.

[58]  P. Płonka,et al.  HGF/SF Increases Number of Skin Melanocytes but Does Not Alter Quality or Quantity of Follicular Melanogenesis , 2013, PloS one.

[59]  E. Sprecher,et al.  Topobiology of human pigmentation: P-cadherin selectively stimulates hair follicle melanogenesis. , 2013, The Journal of investigative dermatology.

[60]  R. Paus,et al.  Loss of γδ T Cells Results in Hair Cycling Defects. , 2013, The Journal of investigative dermatology.

[61]  S. H. Shin,et al.  Hair growth-promoting effects of adiponectin in vitro. , 2012, The Journal of investigative dermatology.

[62]  M. Quon,et al.  Globular adiponectin counteracts VCAM-1-mediated monocyte adhesion via AdipoR1/NF-κB/COX-2 signaling in human aortic endothelial cells. , 2011, American journal of physiology. Endocrinology and metabolism.

[63]  R. Paus,et al.  Thyrotropin-releasing hormone selectively stimulates human hair follicle pigmentation. , 2011, The Journal of investigative dermatology.

[64]  V. Horsley,et al.  Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling , 2011, Cell.

[65]  Takashi Sato,et al.  Adiponectin resides in mouse skin and upregulates hyaluronan synthesis in dermal fibroblasts , 2011, Connective tissue research.

[66]  S. Yusuf,et al.  Ethnic Variation in Adiponectin and Leptin Levels and Their Association With Adiposity and Insulin Resistance , 2010, Diabetes Care.

[67]  R. Paus,et al.  Methods in hair research: how to objectively distinguish between anagen and catagen in human hair follicle organ culture , 2010, Experimental dermatology.

[68]  V. Hearing,et al.  Physiological factors that regulate skin pigmentation , 2009, BioFactors.

[69]  S. Nishimoto,et al.  Effects of adiponectin on growth and differentiation of human keratinocytes--implication of impaired wound healing in diabetes. , 2008, Biochemical and biophysical research communications.

[70]  P. Maini,et al.  Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration , 2008, Nature.

[71]  B. Gower,et al.  Adiponectin is lower among African Americans and is independently related to insulin sensitivity in children and adolescents. , 2005, Diabetes.

[72]  T. Kadowaki,et al.  Adiponectin and adiponectin receptors. , 2005, Endocrine reviews.

[73]  R. Henry,et al.  Adiponectin: more than just another fat cell hormone? , 2003, Diabetes care.

[74]  G. Merlino,et al.  Involvement of hepatocyte growth factor/scatter factor and Met receptor signaling in hair follicle morphogenesis and cycling , 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[75]  W. Pavan,et al.  Hepatocyte growth factor/scatter factor-MET signaling in neural crest-derived melanocyte development. , 1999, Pigment cell research.

[76]  S. Eichmüller,et al.  Distribution and changing density of gamma‐delta T cells in murine skin during the induced hair cycle , 1994, The British journal of dermatology.

[77]  G. Reaven,et al.  Ethnic differences in the relationship between adiponectin and insulin sensitivity in South Asian and Caucasian women. Diabetes Care 31:798-801, 2008 , 2008 .

[78]  R. Halaban,et al.  Met and hepatocyte growth factor/scatter factor signal transduction in normal melanocytes and melanoma cells. , 1992, Oncogene.