Continuous depth-of-interaction encoding using phosphor-coated scintillators

We investigate a novel detector using a lutetium oxyorthosilicate (LSO) scintillator and YGG (yttrium-aluminum-gallium oxide:cerium, Y(3)(Al,Ga)(5)O(12):Ce) phosphor to construct a detector with continuous depth-of-interaction (DOI) information. The far end of the LSO scintillator is coated with a thin layer of YGG phosphor powder which absorbs some fraction of the LSO scintillation light and emits wavelength-shifted photons with a characteristic decay time of approximately 50 ns. The near end of the LSO scintillator is directly coupled to a photodetector. The photodetector detects a mixture of the LSO light and the light emitted by YGG. With appropriate placement of the coating, the ratio of the light converted from the YGG coating with respect to the unconverted LSO light can be made to depend on the interaction depth. DOI information can then be estimated by inspecting the overall light pulse decay time. Experiments were conducted to optimize the coating method. 19 ns decay time differences across the length of the detector were achieved experimentally when reading out a 1.5 x 1.5 x 20 mm(3) LSO crystal with unpolished surfaces and half-coated with YGG phosphor. The same coating scheme was applied to a 4 x 4 LSO array. Pulse shape discrimination (PSD) methods were studied to extract DOI information from the pulse shape changes. The DOI full-width-half-maximum (FWHM) resolution was found to be approximately 8 mm for this 2 cm thick array.

[1]  W. Worstell,et al.  Scintillator crystal readout with wavelength-shifting optical fibers , 1994, Proceedings of 1994 IEEE Nuclear Science Symposium - NSS'94.

[2]  Simon R Cherry,et al.  Measurements of wavelength shifting (WLS) fibre readout for a highly multiplexed, depth-encoding PET detector , 2007, Physics in medicine and biology.

[3]  Jinyi Qi,et al.  A Prototype PET Scanner with DOI-Encoding Detectors , 2008, Journal of Nuclear Medicine.

[4]  William W. Moses,et al.  Design studies for a PET detector module using a PIN photodiode to measure depth of interaction , 1994 .

[5]  H. Murayama,et al.  A four-layer depth of interaction detector block for small animal PET , 2003, 2003 IEEE Nuclear Science Symposium. Conference Record (IEEE Cat. No.03CH37515).

[6]  Huafeng Liu,et al.  Development of a depth of interaction detector for γ-rays , 2001 .

[7]  Bernd J Pichler,et al.  Evaluation of high performance data acquisition boards for simultaneous sampling of fast signals from PET detectors , 2005, Physics in medicine and biology.

[8]  K. Shah,et al.  A reexamination of silicon avalanche photodiode gain and quantum efficiency , 2005, IEEE Nuclear Science Symposium Conference Record, 2005.

[9]  Jurgen Seidel,et al.  Performance evaluation of the GE healthcare eXplore VISTA dual-ring small-animal PET scanner. , 2006, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[10]  Michael V. Green,et al.  Depth identification accuracy of a three layer phoswich PET detector module , 1999 .

[11]  T. Devol,et al.  Comparison of Pulse Shape Discrimination Methods for Phoswich and CsI:Tl Detectors , 2007, IEEE Transactions on Nuclear Science.

[12]  Gerald Entine,et al.  Depth of interaction resolution measurements for a high resolution PET detector using position sensitive avalanche photodiodes , 2006, Physics in medicine and biology.

[13]  Yiping Shao,et al.  Simple charge division readouts for imaging scintillator arrays using a multi-channel PMT , 1995, 1995 IEEE Nuclear Science Symposium and Medical Imaging Conference Record.

[14]  S. Cherry,et al.  Comparison of four depth-encoding PET detector modules with wavelength shifting (WLS) and optical fiber read-out , 2008, Physics in medicine and biology.

[15]  T. Lewellen,et al.  Design of a depth of interaction (DOI) PET detector module , 1997, 1997 IEEE Nuclear Science Symposium Conference Record.

[16]  H. Kudrolli,et al.  Design and performance of a prototype whole-body PET/CT scanner with fiber optic readout , 2004, IEEE Symposium Conference Record Nuclear Science 2004..

[17]  Dominique Sappey-Marinier,et al.  Raytest ClearPET™, a new generation small animal PET scanner , 2007 .

[18]  Thomas K. Lewellen,et al.  Design of a depth of interaction (DOI) PET detector module , 1997 .