Congress of the European Crohn ’ s and Colitis Organisation ( ECCO ) in Vienna , Austria Chairperson :

Disclosure: Prof Panaccione has acted as a consultant and/or advisory board member for Abbott, AbbVie, ActoGeniX, AGI Therapeutics, Alba Therapeutics Albireo, Alfa Wasserman, Amgen, AM-Pharma BV, Anaphore, Aptalis, Astellas, AstraZeneca, Athersys, Atlantic Healthcare, Baxter, BioBalance, Biogen Idec, Boehringer Ingelheim, Bristol-Myers Squibb, Celgene, Celek, Cellerix, Cerimon, ChemoCentryx, CoMentis, Cosmo Technologies, Coronado Biosciences, Cubist, Cytokine PharmaSciences, Eagle, Eisai Medical Research, Elan, EnGene, Eli Lilly, Enteromedics, Exagen Diagnostics, Ferring, Flexion Therapeutics, Funxional Therapeutics, Genentech, Genzyme, Gilead, Given Imaging, GlaxoSmithKline, Hospira, Human Genome Sciences, Ironwood, Janssen, KaloBios, Lexicon, Lycera, Meda, Merck & Co., Merck Research Laboratories, MerckSerono, Millennium, Nisshin Kyorin, Novo Nordisk, NPS Pharmaceuticals, Optimer, Orexigen, PDL Biopharma, Pfizer, Procter and Gamble, Prometheus Laboratories, ProtAb, Purgenesis Technologies, Receptos, Relypsa, Salient, Salix, Santarus, Shire Pharmaceuticals, Sigmoid Pharma, Sirtris (a GSK company), S.L.A. Pharma (UK), Targacept, Takeda, Teva, Therakos, Tillotts, TxCell SA, UCB Pharma, Vascular Biogenics, Viamet, and Warner Chilcott UK; and as a speaker for AbbVie, Aptalis, AstraZeneca, Ferring, Janssen, Merck, Prometheus, Shire, and Takeda. Dr Halfvarson has acted as a consultant and/or received speaker fees from AbbVie, Celgene, Hospira, Janssen, Medivir, MSD, Pfizer, Renapharma-Vifor, Sandoz, Shire, Takeda, and Tillotts. Dr Bossuyt has received advisory board and/or speaker fees from AbbVie, Dr Falk Benelux, Hospira, Janssen, MSD, Mundipharma, Pfizer, Roche, Takeda, and Vifor Pharma.

[1]  G. D'Haens,et al.  325 - Factors Driving Treatment Escalation in Crohn's Disease in the Calm Trial , 2018 .

[2]  S. Travis,et al.  Su1796 - Biomarker Correlation with Endoscopic Outcomes in Patients with Crohn's Disease: Data from Calm , 2018 .

[3]  G. D'Haens,et al.  DOP065 Long-term cost-effectiveness of tight control for Crohn’s disease with adalimumab-based treatment: economic evaluation beyond 48 weeks of CALM trial , 2018 .

[4]  G. D'Haens,et al.  DOP071 Tight control with adalimumab-based treatment is associated with improved quality of life outcomes in patients with moderate to severely active Crohn’s disease: data from CALM , 2018 .

[5]  D. Hommes,et al.  Effect of tight control management on Crohn's disease (CALM): a multicentre, randomised, controlled phase 3 trial , 2017, The Lancet.

[6]  P. Rutgeerts,et al.  A Treat to Target Approach Decreases the Rate of CD-Related Adverse Outcomes versus a Clinical Approach in Patients With Moderate to Severely Active Crohnʼs Disease: Data From CALM 2017 ACG Governors Award for Excellence in Clinical Research: 598 , 2017 .

[7]  C. Langner,et al.  Third European Evidence-based Consensus on Diagnosis and Management of Ulcerative Colitis. Part 1: Definitions, Diagnosis, Extra-intestinal Manifestations, Pregnancy, Cancer Surveillance, Surgery, and Ileo-anal Pouch Disorders. , 2017, Journal of Crohn's & colitis.

[8]  C. Siegel,et al.  Real-World Treatment Pathway Visualizations Show Low Use of Biologic Therapies in Crohn's Disease and Ulcerative Colitis in the United States , 2017 .

[9]  P. Rutgeerts,et al.  Superior Endoscopic and Deep Remission Outcomes in Adults with Moderate to Severe Crohn's Disease Managed with Treat to Target Approach Versus Clinical Symptoms: Data from Calm , 2017 .

[10]  M. Dubinsky,et al.  Fecal Calprotectin Levels Predict Histological Healing in Ulcerative Colitis , 2016, Inflammatory bowel diseases.

[11]  H. Tilg,et al.  3rd European Evidence-based Consensus on the Diagnosis and Management of Crohn’s Disease 2016: Part 1 Diagnosis and Medical Management , 2017, Journal of Crohn's & colitis.

[12]  S. Ng,et al.  Understanding and Preventing the Global Increase of Inflammatory Bowel Disease. , 2017, Gastroenterology.

[13]  L. Peyrin-Biroulet,et al.  Management Strategies to Improve Outcomes of Patients With Inflammatory Bowel Diseases. , 2017, Gastroenterology.

[14]  M. Regueiro,et al.  Silent Crohn's Disease Predicts Increased Bowel Damage During Multiyear Follow-up: The Consequences of Under-reporting Active Inflammation , 2016, Inflammatory bowel diseases.

[15]  J. Halfvarson,et al.  The prognostic significance of faecal calprotectin in patients with inactive inflammatory bowel disease , 2016, Alimentary pharmacology & therapeutics.

[16]  J. Sung,et al.  Asia Pacific Consensus Statements on Crohn's disease. Part 1: Definition, diagnosis, and epidemiology , 2016, Journal of gastroenterology and hepatology.

[17]  A. Bitton,et al.  Early combined immunosuppression for the management of Crohn's disease (REACT): a cluster randomised controlled trial , 2015, The Lancet.

[18]  T. Murdoch,et al.  Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE): Determining Therapeutic Goals for Treat-to-Target , 2015, The American Journal of Gastroenterology.

[19]  Steven J Brown,et al.  Measurement of fecal calprotectin improves monitoring and detection of recurrence of Crohn's disease after surgery. , 2015, Gastroenterology.

[20]  Subrata Ghosh Inflammatory bowel disease: Appreciating disability and impact of disease. , 2015, Canadian journal of gastroenterology & hepatology.

[21]  L. Öhman,et al.  The intra-individual variability of faecal calprotectin: a prospective study in patients with active ulcerative colitis. , 2014, Journal of Crohn's & colitis.

[22]  W. Sandborn,et al.  Endoscopic assessment and treating to target increase the likelihood of mucosal healing in patients with Crohn's disease. , 2014, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[23]  G. D'Haens,et al.  Comparison of six different calprotectin assays for the assessment of inflammatory bowel disease , 2014, United European gastroenterology journal.

[24]  J. Belaiche,et al.  Consecutive Fecal Calprotectin Measurements to Predict Relapse in Patients with Ulcerative Colitis Receiving Infliximab Maintenance Therapy , 2013, Inflammatory bowel diseases.

[25]  S. Ng,et al.  First Prospective, Population-Based Inflammatory Bowel Disease Incidence Study in Mainland of China: The Emergence of “Western” Disease , 2013, Inflammatory bowel diseases.

[26]  A. M’Koma,et al.  Inflammatory Bowel Disease: An Expanding Global Health Problem , 2013, Clinical medicine insights. Gastroenterology.

[27]  R. Porcher,et al.  Maintenance of remission among patients with Crohn's disease on antimetabolite therapy after infliximab therapy is stopped. , 2012, Gastroenterology.

[28]  V. Chouraki,et al.  The changing pattern of Crohn’s disease incidence in northern France: a continuing increase in the 10‐ to 19‐year‐old age bracket (1988–2007) , 2011, Alimentary pharmacology & therapeutics.

[29]  K. Kolho,et al.  Faecal calprotectin in children with clinically quiescent inflammatory bowel disease , 2010, Scandinavian journal of gastroenterology.

[30]  J. Mate,et al.  Fecal calprotectin and lactoferrin for the prediction of inflammatory bowel disease relapse , 2009, Inflammatory bowel diseases.

[31]  H. R. Nunes,et al.  Incidence and prevalence rates of inflammatory bowel diseases, in midwestern of São Paulo State, Brazil. , 2009, Arquivos de gastroenterologia.

[32]  R. D'Incà,et al.  Can Calprotectin Predict Relapse Risk in Inflammatory Bowel Disease? , 2008, The American Journal of Gastroenterology.

[33]  M. Bottai,et al.  Calprotectin is a stronger predictive marker of relapse in ulcerative colitis than in Crohn’s disease , 2005, Gut.

[34]  A. Røseth,et al.  Normalization of faecal calprotectin: a predictor of mucosal healing in patients with inflammatory bowel disease , 2004, Scandinavian journal of gastroenterology.

[35]  M. Bala,et al.  Annual cost of care for Crohn's disease: a payor perspective , 2000, American Journal of Gastroenterology.

[36]  I. Bjarnason,et al.  Surrogate markers of intestinal inflammation are predictive of relapse in patients with inflammatory bowel disease. , 2000, Gastroenterology.