Measurement of the base number of DNA using a special calliper made of a split G-quadruplex.

A special DNA calliper made of a split G-quadruplex was constructed to measure the length of DNA in a single-digit base number range between two selected sequences. The enhanced fluorescence of PPIX changed with the distance between two G-rich segments.

[1]  Jiangtao Ren,et al.  Contribution of potassium ion and split modes of G-quadruplex to the sensitivity and selectivity of label-free sensor toward DNA detection using fluorescence. , 2012, Biosensors & bioelectronics.

[2]  Tao Li,et al.  A lead(II)-driven DNA molecular device for turn-on fluorescence detection of lead(II) ion with high selectivity and sensitivity. , 2010, Journal of the American Chemical Society.

[3]  M. Bowers,et al.  B-DNA Helix Stability in a Solvent-Free Environment , 2007, Journal of the American Society for Mass Spectrometry.

[4]  Xiang Zhou,et al.  Highly effective colorimetric and visual detection of nucleic acids using an asymmetrically split peroxidase DNAzyme. , 2008, Journal of the American Chemical Society.

[5]  B. Révet,et al.  Short unligated sticky ends enable the observation of circularised DNA by atomic force and electron microscopies. , 1998, Nucleic acids research.

[6]  P. Bolton,et al.  Fluorescent dyes specific for quadruplex DNA. , 1998, Nucleic acids research.

[7]  Afshin Beheshti,et al.  DNA electrophoresis in agarose gels: A simple relation describing the length dependence of mobility , 2002, Electrophoresis.

[8]  Yiider Tseng,et al.  Effect of length, topology, and concentration on the microviscosity and microheterogeneity of DNA solutions. , 2002, Journal of molecular biology.

[9]  E. Wang,et al.  G-quadruplex DNAzyme based molecular catalytic beacon for label-free colorimetric logic gates. , 2011, Biomaterials.

[10]  C. J. Avers,et al.  Nuclear and mitochondrial DNA from wild-type and petite yeast: circularity, length, and buoyant density. , 1969, Proceedings of the National Academy of Sciences of the United States of America.

[11]  A Paul Alivisatos,et al.  A nanoplasmonic molecular ruler for measuring nuclease activity and DNA footprinting , 2006, Nature nanotechnology.

[12]  Dipankar Sen,et al.  A catalytic DNA for porphyrin metallation , 1996, Nature Structural Biology.

[13]  Tao Li,et al.  Parallel G-quadruplex-specific fluorescent probe for monitoring DNA structural changes and label-free detection of potassium ion. , 2010, Analytical chemistry.

[14]  Yingfu Li,et al.  Recognition of anionic porphyrins by DNA aptamers. , 1996, Biochemistry.

[15]  Yingfu Li,et al.  DNA-enhanced peroxidase activity of a DNA-aptamer-hemin complex. , 1998, Chemistry & biology.

[16]  W. Gilbert,et al.  Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis , 1988, Nature.

[17]  S. Weiss.  Fluorescence spectroscopy of single biomolecules. , 1999, Science.

[18]  A. Skalka,et al.  Characterization of the Self Association of Avian Sarcoma Virus Integrase by Analytical Ultracentrifugation* , 1999, The Journal of Biological Chemistry.

[19]  Wei Yang,et al.  Peroxidase activity-structure relationship of the intermolecular four-stranded G-quadruplex-hemin complexes and their application in Hg2+ ion detection. , 2009, Talanta.