A Cdt1–geminin complex licenses chromatin for DNA replication and prevents rereplication during S phase in Xenopus
暂无分享,去创建一个
[1] M. DePamphilis,et al. Regulating the licensing of DNA replication origins in metazoa. , 2006, Current opinion in cell biology.
[2] A. Giordano,et al. Role of geminin: from normal control of DNA replication to cancer formation and progression? , 2006, Cell Death and Differentiation.
[3] Anindya Dutta,et al. PCNA Is a Cofactor for Cdt1 Degradation by CUL4/DDB1-mediated N-terminal Ubiquitination* , 2006, Journal of Biological Chemistry.
[4] K. Nakayama,et al. Two E3 ubiquitin ligases, SCF‐Skp2 and DDB1‐Cul4, target human Cdt1 for proteolysis , 2006, The EMBO journal.
[5] Y. Xiong,et al. An Evolutionarily Conserved Function of Proliferating Cell Nuclear Antigen for Cdt1 Degradation by the Cul4-Ddb1 Ubiquitin Ligase in Response to DNA Damage* , 2006, Journal of Biological Chemistry.
[6] M. Méchali,et al. Mitotic Remodeling of the Replicon and Chromosome Structure , 2005, Cell.
[7] Anindya Dutta,et al. Right Place, Right Time, and Only Once: Replication Initiation in Metazoans , 2005, Cell.
[8] K. Kroll,et al. Geminin regulates neuronal differentiation by antagonizing Brg1 activity. , 2005, Genes & development.
[9] M. Kessel,et al. The regulation of embryonic patterning and DNA replication by geminin , 2005, Cellular and Molecular Life Sciences CMLS.
[10] J. Blow,et al. Cdt1 downregulation by proteolysis and geminin inhibition prevents DNA re‐replication in Xenopus , 2005, The EMBO journal.
[11] M. Méchali,et al. Recombinant Cdt1 Induces Rereplication of G2 Nuclei in Xenopus Egg Extracts , 2005, Current Biology.
[12] J. Blow,et al. Functional domains of the Xenopus replication licensing factor Cdt1 , 2005, Nucleic acids research.
[13] Kazumasa Yoshida,et al. Intrinsic nuclear import activity of geminin is essential to prevent re‐initiation of DNA replication in Xenopus eggs , 2004, Genes to cells : devoted to molecular & cellular mechanisms.
[14] J. Walter,et al. Replication-dependent destruction of Cdt1 limits DNA replication to a single round per cell cycle in Xenopus egg extracts. , 2005, Genes & development.
[15] T. McGarry,et al. Geminin Has Dimerization, Cdt1-binding, and Destruction Domains That Are Required for Biological Activity* , 2004, Journal of Biological Chemistry.
[16] A. Bielinsky,et al. Mcm10 regulates the stability and chromatin association of DNA polymerase-alpha. , 2004, Molecular cell.
[17] K. Stoeber,et al. Molecular structure of human geminin , 2004, Nature Structural &Molecular Biology.
[18] Michael A. Gonzalez,et al. Geminin predicts adverse clinical outcome in breast cancer by reflecting cell‐cycle progression , 2004, The Journal of pathology.
[19] C. Dumas,et al. Crystal structure of the coiled-coil dimerization motif of geminin: structural and functional insights on DNA replication regulation. , 2004, Journal of molecular biology.
[20] Yunje Cho,et al. Structural basis for inhibition of the replication licensing factor Cdt1 by geminin , 2004, Nature.
[21] K. Helin,et al. Human Geminin promotes pre‐RC formation and DNA replication by stabilizing CDT1 in mitosis , 2004, The EMBO journal.
[22] Anindya Dutta,et al. Rereplication by Depletion of Geminin Is Seen Regardless of p53 Status and Activates a G2/M Checkpoint , 2004, Molecular and Cellular Biology.
[23] D. Takeda,et al. A dimerized coiled-coil domain and an adjoining part of geminin interact with two sites on Cdt1 for replication inhibition. , 2004, Molecular cell.
[24] T. Nishimoto,et al. Proteolysis of DNA Replication Licensing Factor Cdt1 in S-phase Is Performed Independently of Geminin through Its N-terminal Region* , 2004, Journal of Biological Chemistry.
[25] J. Bartek,et al. Loss of Geminin induces rereplication in the presence of functional p53 , 2004, The Journal of cell biology.
[26] Y. Tatsumi,et al. Cdt1 Phosphorylation by Cyclin A-dependent Kinases Negatively Regulates Its Function without Affecting Geminin Binding* , 2004, Journal of Biological Chemistry.
[27] Xiaohua Wu,et al. Cyclin-dependent Kinases Phosphorylate Human Cdt1 and Induce Its Degradation* , 2004, Journal of Biological Chemistry.
[28] M. Méchali,et al. Cell cycle regulation of the licensing activity of Cdt1 in Xenopus laevis. , 2004, Experimental cell research.
[29] J. Nevins,et al. The Regulated Association of Cdt1 with Minichromosome Maintenance Proteins and Cdc6 in Mammalian Cells* , 2004, Journal of Biological Chemistry.
[30] Filippo Del Bene,et al. Direct interaction of geminin and Six3 in eye development , 2004, Nature.
[31] M. Kessel,et al. The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactions , 2004, Nature.
[32] N. Walworth,et al. Phosphorylation activates Chk1 and is required for checkpoint-mediated cell cycle arrest , 2002, Journal of Cell Science.
[33] T. Mizuno,et al. Mouse Geminin Inhibits Not Only Cdt1-MCM6 Interactions but Also a Novel Intrinsic Cdt1 DNA Binding Activity* , 2002, The Journal of Biological Chemistry.
[34] T. McGarry. Geminin deficiency causes a Chk1-dependent G2 arrest in Xenopus. , 2002, Molecular biology of the cell.
[35] J. Kutok,et al. Expression of geminin as a marker of cell proliferation in normal tissues and malignancies. , 2002, The American journal of pathology.
[36] J. Blow,et al. Geminin Becomes Activated as an Inhibitor of Cdt1/RLF-B Following Nuclear Import , 2002, Current Biology.
[37] Seiji Tanaka,et al. Interdependent nuclear accumulation of budding yeast Cdt1 and Mcm2–7 during G1 phase , 2002, Nature Cell Biology.
[38] Ueli Aebi,et al. Modular self‐assembly of a Y‐shaped multiprotein complex from seven nucleoporins , 2002, The EMBO journal.
[39] Anindya Dutta,et al. DNA replication in eukaryotic cells. , 2002, Annual review of biochemistry.
[40] Zoi Lygerou,et al. The Human Licensing Factor for DNA Replication Cdt1 Accumulates in G1 and Is Destabilized after Initiation of S-phase* , 2001, The Journal of Biological Chemistry.
[41] T. McGarry,et al. The Drosophila Geminin homolog: roles for Geminin in limiting DNA replication, in anaphase and in neurogenesis. , 2001, Genes & development.
[42] M. Méchali,et al. Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin , 2001, Nature Cell Biology.
[43] J A Wohlschlegel,et al. Inhibition of eukaryotic DNA replication by geminin binding to Cdt1. , 2000, Science.
[44] A. Kumagai,et al. Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts. , 2000, Genes & development.
[45] S. Elledge,et al. Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint. , 2000, Genes & development.
[46] J. Moreau,et al. XCDT1 is required for the assembly of pre-replicative complexes in Xenopus laevis , 2000, Nature.
[47] M. Méchali,et al. Stepwise Regulated Chromatin Assembly of MCM2–7 Proteins* , 2000, The Journal of Biological Chemistry.
[48] M. Kirschner,et al. Geminin, an Inhibitor of DNA Replication, Is Degraded during Mitosis , 1998, Cell.
[49] J. Blow,et al. A role for the nuclear envelope in controlling DNA replication within the cell cycle , 1988, Nature.