论文信息 - A Geometric Model for the Lumen of Blood Vessels in X-ray Angiography

A Geometric Model for the Lumen of Blood Vessels in X-ray Angiography

We have developed a model for representing the image of segments of blood vessels in x-ray angiograms, and a software package for generating the model from digitized angiograms. The model is based on projections of linearly tapering cylinders and is suitable for the analysis of vessel lumen position, size and shape. This is of interest for research into the disease atherosclerosis. The system has been validated using a set of post mortem samples. The accuracy of representation of the lumen radius is between + 0% and +10% (95% confidence limits) and the accuracy of simple shape information is 81%.

David J. Hawkes | Alan C. F. Colchester | Charles R. Hardingham

[1] D C Levin,et al. Significance of the Angiographic Morphology of Localized Coronary Stenoses: Histopathologic Correlations , 1982, Circulation.

[2] V. Fuster,et al. Angiographic evolution of coronary artery morphology in unstable angina. , 1986, Journal of the American College of Cardiology.

[3] D J Hawkes,et al. Matching of geometric models in the analysis of lumen shape in digital X-ray angiography. , 1991, Progress in clinical and biological research.

[4] Dana H. Ballard,et al. Computer Vision , 1982 .

[5] B G Brown,et al. Coronary Vasospasm: Observations Linking the Clinical Spectrum of Ischemic Heart Disease to the Dynamic Pathology of Coronary Atherosclerosis , 1981 .

[6] Riccardo Guzzardi. Physics and engineering of medical imaging , 1987 .