Traffic-related air pollution associated with prevalence of asthma and COPD / chronic bronchitis . A cross-sectional study in Southern Sweden

Background: There is growing evidence that air pollution from traffic has adverse long-term effects on chronic respiratory disease in children, but there are few studies and more inconclusive results in adults. We examined associations between residential traffic and asthma and COPD in adults in southern Sweden. A postal questionnaire in 2000 (n = 9319, 18–77 years) provided disease status, and self-reported exposure to traffic. A Geographical Information System (GIS) was used to link geocoded residential addresses to a Swedish road database and an emission database for NOx. Results: Living within 100 m of a road with >10 cars/minute (compared with having no heavy road within this distance) was associated with prevalence of asthma diagnosis (OR = 1.40, 95% CI = 1.04–1.89), and COPD diagnosis (OR = 1.64, 95%CI = 1.11–2.4), as well as asthma and chronic bronchitis symptoms. Self-reported traffic exposure was associated with asthma diagnosis and COPD diagnosis, and with asthma symptoms. Annual average NOx was associated with COPD diagnosis and symptoms of asthma and chronic bronchitis. Conclusion: Living close to traffic was associated with prevalence of asthma diagnosis, COPD diagnosis, and symptoms of asthma and bronchitis. This indicates that traffic-related air pollution has both long-term and short-term effects on chronic respiratory disease in adults, even in a region with overall low levels of air pollution. Background Traffic-related air pollution is well known to have shortterm effects on chronic respiratory disease, exacerbating symptoms and increasing hospital admissions for respiratory causes [1]. Strong effects on symptoms have also been observed in areas with relatively low background pollution [2]. Long-term effects have been disputed, but there is growing evidence that traffic-related air pollution is related, at least among children, to asthma incidence [37], decreased lung function development [8,9], and incidence of bronchitic symptoms [4,10]. Published: 20 January 2009 International Journal of Health Geographics 2009, 8:2 doi:10.1186/1476-072X-8-2 Received: 2 October 2008 Accepted: 20 January 2009 This article is available from: http://www.ij-healthgeographics.com/content/8/1/2 © 2009 Lindgren et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

[1]  D. Jarvis,et al.  Home Outdoor NO2 and New Onset of Self-Reported Asthma in Adults , 2009, Epidemiology.

[2]  C. Löfdahl,et al.  Specific nasal symptoms and symptom‐provoking factors may predict increased risk of developing COPD , 2008, Clinical physiology and functional imaging.

[3]  Kiros Berhane,et al.  Traffic-Related Air Pollution and Asthma Onset in Children: A Prospective Cohort Study with Individual Exposure Measurement , 2008, Environmental health perspectives.

[4]  Abigail S. Hoats,et al.  Residential Traffic and Children’s Respiratory Health , 2008, Environmental health perspectives.

[5]  Mats Gustafsson,et al.  Properties and toxicological effects of particles from the interaction between tyres, road pavement and winter traction material. , 2008, The Science of the total environment.

[6]  J. Halonen,et al.  Urban air pollution, and asthma and COPD hospital emergency room visits , 2008, Thorax.

[7]  Bert Brunekreef,et al.  Residential Outdoor Air Pollution and Lung Function in Schoolchildren , 2008, Epidemiology.

[8]  Frank D Gilliland,et al.  Recent evidence for adverse effects of residential proximity to traffic sources on asthma , 2008, Current opinion in pulmonary medicine.

[9]  B. Forsberg,et al.  Perceived annoyance and asthmatic symptoms in relation to vehicle exhaust levels outside home: a cross-sectional study , 2007, Environmental health : a global access science source.

[10]  D. Mannino,et al.  Global burden of COPD: risk factors, prevalence, and future trends , 2007, The Lancet.

[11]  U. Ackermann-Liebrich,et al.  Characterization of Source-Specific Air Pollution Exposure for a Large Population-Based Swiss Cohort (SAPALDIA) , 2007, Environmental health perspectives.

[12]  Mats Gustafsson,et al.  Wear particles generated from studded tires and pavement induces inflammatory reactions in mouse macrophage cells. , 2007, Chemical research in toxicology.

[13]  Jonathan I Levy,et al.  Factors influencing the spatial extent of mobile source air pollution impacts: a meta-analysis , 2007, BMC public health.

[14]  D. Postma,et al.  Air pollution and development of asthma, allergy and infections in a birth cohort , 2007, European Respiratory Journal.

[15]  Yifang Zhu,et al.  In-cabin commuter exposure to ultrafine particles on Los Angeles freeways. , 2007, Environmental science & technology.

[16]  Kiros Berhane,et al.  Effect of exposure to traffic on lung development from 10 to 18 years of age: a cohort study , 2007, The Lancet.

[17]  Christian Schindler,et al.  Living near main streets and respiratory symptoms in adults: the Swiss Cohort Study on Air Pollution and Lung Diseases in Adults. , 2006, American journal of epidemiology.

[18]  D. Jarvis,et al.  Chronic bronchitis and urban air pollution in an international study. , 2006, Occupational and environmental medicine.

[19]  Giovanni Viegi,et al.  Epidemiology of chronic obstructive pulmonary disease: Health effects of air pollution , 2006, Respirology.

[20]  U Gehring,et al.  Respiratory health and individual estimated exposure to traffic-related air pollutants in a cohort of young children , 2006, Occupational and Environmental Medicine.

[21]  B. Forsberg,et al.  Vehicle exhaust exposure in an incident case–control study of adult asthma , 2006, European Respiratory Journal.

[22]  Joachim Heinrich,et al.  Long-term air pollution exposure and living close to busy roads are associated with COPD in women , 2005, Respiratory research.

[23]  P. Pilesjö,et al.  Are associations between socio-economic characteristics and exposure to air pollution a question of study area size? An example from Scania, Sweden , 2005, International Journal of Health Geographics.

[24]  D. Johns,et al.  Biological dust exposure in the workplace is a risk factor for chronic obstructive pulmonary disease , 2005, Thorax.

[25]  F. Forastiere,et al.  Self report and GIS based modelling as indicators of air pollution exposure: is there a gold standard? , 2005, Occupational and Environmental Medicine.

[26]  Joachim Heinrich,et al.  Traffic at residential address, respiratory health, and atopy in adults: the National German Health Survey 1998. , 2005, Environmental research.

[27]  Bert Brunekreef,et al.  Air pollution from traffic and the development of respiratory infections and asthmatic and allergic symptoms in children. , 2002, American journal of respiratory and critical care medicine.

[28]  R. de Marco,et al.  The impact of climate and traffic‐related NO2 on the prevalence of asthma and allergic rhinitis in Italy , 2002, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[29]  L. Lindholm,et al.  Prevalence of obstructive lung diseases and respiratory symptoms in relation to living environment and socio-economic group. , 2001, Respiratory medicine.

[30]  N. Künzli,et al.  Long-term health effects of particulate and other ambient air pollution: research can progress faster if we want it to. , 2000, Environmental health perspectives.

[31]  U Ackermann-Liebrich,et al.  Exposure to motor vehicle traffic and allergic sensitization. The Swiss Study on Air Pollution and Lung Diseases in Adults (SAPALDIA) Team. , 2000, Epidemiology.

[32]  U Ackermann-Liebrich,et al.  Long-term ambient air pollution and respiratory symptoms in adults (SAPALDIA study). The SAPALDIA Team. , 1999, American journal of respiratory and critical care medicine.

[33]  C. Kirby,et al.  Temporal and Spatial Variations in Nitrogen Dioxide Concentrations Across an Urban Landscape: Cambridge, UK , 1998 .

[34]  Bert Brunekreef,et al.  Air Pollution from Truck Traffic and Lung Function in Children Living near Motorways , 1997, Epidemiology.

[35]  S Greenland,et al.  Modeling and variable selection in epidemiologic analysis. , 1989, American journal of public health.

[36]  张锺儒,et al.  对急性哮喘加剧的成年患者两种不同教育干预的评价[英]/Co^^té J…∥Am J Respir Crit Care Med , 2002 .

[37]  Uppbyggnad Och Validering Av Emissionsdatabas Avseende Luftföroreningar För Skåne Med Basår 2001 , 2022 .