Studying the oxidative stress paradigm in vitro: a theoretical and practical perspective.

[1]  O. Schmid,et al.  Realistic Exposure Methods for Investigating the Interaction of Nanoparticles with the Lung at the Air-Liquid Interface In Vitro , 2011 .

[2]  Craig A. Poland,et al.  Asbestos, carbon nanotubes and the pleural mesothelium: a review of the hypothesis regarding the role of long fibre retention in the parietal pleura, inflammation and mesothelioma , 2010, Particle and Fibre Toxicology.

[3]  Christian Mühlfeld,et al.  In vitro models of the human epithelial airway barrier to study the toxic potential of particulate matter , 2008, Expert opinion on drug metabolism & toxicology.

[4]  Craig A. Poland,et al.  Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study. , 2008, Nature nanotechnology.

[5]  David M. Brown,et al.  The effect of oxidative stress on macrophages and lung epithelial cells: the role of phosphodiesterases 1 and 4. , 2007, Toxicology letters.

[6]  Roel P F Schins,et al.  Genotoxicity of Poorly Soluble Particles , 2007, Inhalation toxicology.

[7]  David M. Brown,et al.  Proinflammogenic Effects of Low-Toxicity and Metal Nanoparticles In Vivo and In Vitro: Highlighting the Role of Particle Surface Area and Surface Reactivity , 2007, Inhalation toxicology.

[8]  Catrin Albrecht,et al.  Cellular responses to nanoparticles: Target structures and mechanisms , 2007 .

[9]  Lang Tran,et al.  Safe handling of nanotechnology , 2006, Nature.

[10]  Mark R Wiesner,et al.  Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm. , 2006, Nano letters.

[11]  Robert N Grass,et al.  Oxide nanoparticle uptake in human lung fibroblasts: effects of particle size, agglomeration, and diffusion at low concentrations. , 2005, Environmental science & technology.

[12]  J. Heyder,et al.  Instillation of Six Different Ultrafine Carbon Particles Indicates a Surface Area Threshold Dose for Acute Lung Inflammation in Mice , 2005, Environmental health perspectives.

[13]  G. Oberdörster,et al.  Nanotoxicology: An Emerging Discipline Evolving from Studies of Ultrafine Particles , 2005, Environmental health perspectives.

[14]  Barbara Thorand,et al.  Cardiovascular effects of fine and ultrafine particles. , 2005, Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine.

[15]  J Schwartz,et al.  The effects of particulate air pollution on daily deaths: a multi-city case crossover analysis , 2004, Occupational and Environmental Medicine.

[16]  A Plasencia,et al.  Apheis: public health impact of PM10 in 19 European cities , 2004, Journal of Epidemiology and Community Health.

[17]  David M. Brown,et al.  Calcium and ROS-mediated activation of transcription factors and TNF-alpha cytokine gene expression in macrophages exposed to ultrafine particles. , 2003, American journal of physiology. Lung cellular and molecular physiology.

[18]  J. Schwartz,et al.  The temporal pattern of respiratory and heart disease mortality in response to air pollution. , 2003, Environmental health perspectives.

[19]  Vicki Stone,et al.  Oxidative stress and calcium signaling in the adverse effects of environmental particles (PM10). , 2003, Free radical biology & medicine.

[20]  A. Nel,et al.  Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage. , 2002, Environmental health perspectives.

[21]  K. Donaldson,et al.  Interactions between ultrafine particles and transition metals in vivo and in vitro. , 2002, Toxicology and applied pharmacology.

[22]  W. MacNee,et al.  Oxidative stress and lung inflammation in airways disease. , 2001, European journal of pharmacology.

[23]  David M. Brown,et al.  Size-dependent proinflammatory effects of ultrafine polystyrene particles: a role for surface area and oxidative stress in the enhanced activity of ultrafines. , 2001, Toxicology and applied pharmacology.

[24]  Ken Donaldson,et al.  Education: Ultrafine Particles , 2001 .

[25]  David M. Brown,et al.  Increased inflammation and intracellular calcium caused by ultrafine carbon black is independent of transition metals or other soluble components , 2000, Occupational and environmental medicine.

[26]  David M. Brown,et al.  Increased calcium influx in a monocytic cell line on exposure to ultrafine carbon black. , 2000, The European respiratory journal.

[27]  David M. Brown,et al.  Ultrafine Particle-Mediated Activation of Macrophages: Intracellular Calcium Signaling and Oxidative Stress , 2000, Inhalation toxicology.

[28]  David M. Brown,et al.  The role of oxidative stress in the prolonged inhibitory effect of ultrafine carbon black on epithelial cell function. , 1998, Toxicology in vitro : an international journal published in association with BIBRA.

[29]  W. MacNee,et al.  In vivo and in vitro proinflammatory effects of particulate air pollution (PM10). , 1997, Environmental health perspectives.

[30]  A. Peters,et al.  Respiratory effects are associated with the number of ultrafine particles. , 1997, American journal of respiratory and critical care medicine.

[31]  W. MacNee,et al.  Particulate air pollution and acute health effects , 1995, The Lancet.

[32]  K. Schulze-Osthoff,et al.  Functions of glutathione and glutathione disulfide in immunology and immunopathology , 1994, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[33]  D. Dockery,et al.  An association between air pollution and mortality in six U.S. cities. , 1993, The New England journal of medicine.

[34]  G. Oberdörster,et al.  Pulmonary retention of ultrafine and fine particles in rats. , 1992, American journal of respiratory cell and molecular biology.

[35]  A. Abbas,et al.  Cellular and Molecular Immunology , 1991 .

[36]  R. Tsien,et al.  A new generation of Ca2+ indicators with greatly improved fluorescence properties. , 1985, The Journal of biological chemistry.

[37]  R. Hilf,et al.  A fluorometric method for determination of oxidized and reduced glutathione in tissues. , 1976, Analytical biochemistry.

[38]  Martin J. D. Clift,et al.  Nanotoxicology: a perspective and discussion of whether or not in vitro testing is a valid alternative , 2010, Archives of Toxicology.

[39]  Andrew D Maynard,et al.  Nanotechnology: the next big thing, or much ado about nothing? , 2007, The Annals of occupational hygiene.

[40]  Dana Loomis,et al.  Work in Brief , 2006 .

[41]  David M. Brown,et al.  The Importance of Surface Area and Specific Reactivity in the Acute Pulmonary Inflammatory Response to Particles , 2002 .

[42]  W. MacNee,et al.  Short-term inflammatory responses following intratracheal instillation of fine and ultrafine carbon black in rats. , 1999, Inhalation toxicology.

[43]  P. Morrow,et al.  Volumetric loading of alveolar macrophages (AM): a possible basis for diminished AM-mediated particle clearance. , 1992, Experimental lung research.