A Computer Simulation Approach to Assessing Therapeutic Intervention Points for the Prevention of Cytokine-Induced Cartilage Breakdown
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A. Rowan | T. Cawston | CJ Proctor | C Macdonald | JM Milner | AD Rowan | TE Cawston | T. Cawston | C. Macdonald | J. Milner | Cj Proctor | A. Rowan | Jm Milner | Christopher D. Macdonald | Carole J. Proctor
[1] M Kashiwagi,et al. TIMP-3 Is a Potent Inhibitor of Aggrecanase 1 (ADAM-TS4) and Aggrecanase 2 (ADAM-TS5)* , 2001, The Journal of Biological Chemistry.
[2] J. Dudhia,et al. JAK/STAT but Not ERK1/ERK2 Pathway Mediates Interleukin (IL)-6/Soluble IL-6R Down-regulation of Type II Collagen, Aggrecan Core, and Link Protein Transcription in Articular Chondrocytes , 2003, The Journal of Biological Chemistry.
[3] K. Tanzawa,et al. Inhibition of ADAMTS4 (aggrecanase‐1) by tissue inhibitors of metalloproteinases (TIMP‐1, 2, 3 and 4) , 2001, FEBS letters.
[4] Sang-Gu Hwang,et al. c-Jun/Activator Protein-1 Mediates Interleukin-1β-induced Dedifferentiation but Not Cyclooxygenase-2 Expression in Articular Chondrocytes* , 2005, Journal of Biological Chemistry.
[5] Samik Ghosh,et al. Erratum: The Systems Biology Graphical Notation , 2009, Nature Biotechnology.
[6] A. Schmidt,et al. Characterization and Functional Analysis of the Promoter of RAGE, the Receptor for Advanced Glycation End Products* , 1997, The Journal of Biological Chemistry.
[7] John C. Lee,et al. Actions of IL-1 are selectively controlled by p38 mitogen-activated protein kinase: regulation of prostaglandin H synthase-2, metalloproteinases, and IL-6 at different levels. , 1997, Journal of immunology.
[8] R. Finke,et al. Protein aggregation kinetics, mechanism, and curve-fitting: a review of the literature. , 2009, Biochimica et biophysica acta.
[9] N. Kikuchi,et al. CellDesigner 3.5: A Versatile Modeling Tool for Biochemical Networks , 2008, Proceedings of the IEEE.
[10] Darren J. Wilkinson,et al. Tools for the SBML Community , 2006, Bioinform..
[11] B. Bresnihan,et al. Treatment of rheumatoid arthritis with interleukin 1 receptor antagonist , 1999, Annals of the rheumatic diseases.
[12] U Klingmüller,et al. Predictive mathematical models of cancer signalling pathways , 2012, Journal of internal medicine.
[13] J. Rutter,et al. Synergistic induction of matrix metalloproteinase 1 by interleukin-1alpha and oncostatin M in human chondrocytes involves signal transducer and activator of transcription and activator protein 1 transcription factors via a novel mechanism. , 2001, Arthritis and rheumatism.
[14] A. Rowan,et al. Adenoviral gene transfer of interleukin-1 in combination with oncostatin M induces significant joint damage in a murine model. , 2003, The American journal of pathology.
[15] J. Heath,et al. Synergistic effects of glycoprotein 130 binding cytokines in combination with interleukin-1 on cartilage collagen breakdown. , 2001, Arthritis and rheumatism.
[16] G. Lisignoli,et al. Paradoxical effects of tissue inhibitor of metalloproteinases 1 gene transfer in collagen-induced arthritis. , 2001, Arthritis and rheumatism.
[17] R. Wait,et al. Induction of interleukin-1 in articular cartilage by explantation and cutting. , 2004, Arthritis and rheumatism.
[18] W. Ferrell,et al. Matriptase is a novel initiator of cartilage matrix degradation in osteoarthritis. , 2010, Arthritis and rheumatism.
[19] Melanie I. Stefan,et al. BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models , 2010, BMC Systems Biology.
[20] Mudita Singhal,et al. COPASI - a COmplex PAthway SImulator , 2006, Bioinform..
[21] D. Hochbaum,et al. Phosphorylation of c-Fos by Members of the p38 MAPK Family , 2005, Journal of Biological Chemistry.
[22] J. Raynauld,et al. Quantitative imaging of the structural changes of osteoarthritis: An exciting challenge for the new millennium , 2001, Current rheumatology reports.
[23] D. Zukor,et al. Role of interleukin-1 and tumor necrosis factor alpha in matrix degradation of human osteoarthritic cartilage. , 2005, Arthritis and rheumatism.
[24] P. Linsley,et al. Identification and characterization of cellular receptors for the growth regulator, oncostatin M. , 1989, The Journal of biological chemistry.
[25] Hadley Wickham,et al. ggplot2 - Elegant Graphics for Data Analysis (2nd Edition) , 2017 .
[26] M. Goldring,et al. The role of oncostatin M in animal and human connective tissue collagen turnover and its localization within the rheumatoid joint. , 1998, Arthritis and rheumatism.
[27] Sarala M. Wimalaratne,et al. The Systems Biology Graphical Notation , 2009, Nature Biotechnology.
[28] T E Cawston,et al. Activation of procollagenases is a key control point in cartilage collagen degradation: interaction of serine and metalloproteinase pathways. , 2001, Arthritis and rheumatism.
[29] A. Rowan,et al. Collagenase gene regulation by pro-inflammatory cytokines in cartilage. , 2007, Frontiers in bioscience : a journal and virtual library.
[30] C. Brinckerhoff,et al. Matrix metalloproteinases: role in arthritis. , 2006, Frontiers in bioscience : a journal and virtual library.
[31] Darren J. Wilkinson. Stochastic Modelling for Systems Biology , 2006 .
[32] M. Sporn,et al. The triterpenoid CDDO inhibits expression of matrix metalloproteinase-1, matrix metalloproteinase-13 and Bcl-3 in primary human chondrocytes , 2003, Arthritis research & therapy.
[33] A. Rowan,et al. Synergistic Collagenase Expression and Cartilage Collagenolysis Are Phosphatidylinositol 3-Kinase/Akt Signaling-dependent* , 2008, Journal of Biological Chemistry.
[34] Hiroaki Kitano,et al. The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models , 2003, Bioinform..
[35] T. Cawston,et al. Matrix metalloproteinase knockout studies and the potential use of matrix metalloproteinase inhibitors in the rheumatic diseases. , 2005, Current drug targets. Inflammation and allergy.
[36] C. Sen,et al. Antioxidant and redox regulation of gene transcription , 1996, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[37] A. Rowan,et al. Interleukin-1 in combination with oncostatin M up-regulates multiple genes in chondrocytes: implications for cartilage destruction and repair. , 2006, Arthritis and rheumatism.
[38] D. Edwards,et al. The Human Tissue Inhibitor of Metalloproteinases (TIMP)-1 Gene Contains Repressive Elements within the Promoter and Intron 1* , 2000, The Journal of Biological Chemistry.
[39] D. Noble. Modeling the Heart--from Genes to Cells to the Whole Organ , 2002, Science.
[40] D. Gillespie. Exact Stochastic Simulation of Coupled Chemical Reactions , 1977 .
[41] P. Heinrich,et al. Oncostatin M Receptor-mediated Signal Transduction Is Negatively Regulated by SOCS3 through a Receptor Tyrosine-independent Mechanism* , 2006, Journal of Biological Chemistry.