Interactions of the pineal and exposure to continuous light on organ weights of female rats.

Either exposure to constant light for 80 days or pinealectomy produced similar changes in the weights of the ovaries and adrenals of female rats. These were not additive when both procedures were employed. Pinealectomy did not share with light-exposure the capacity to induce uterine hypertrophy. Rats exposed to constant light for 56 days had lighter pineals than animals kept in darkness; this decrease was not affected by administration of bovine pineal extracts. The increase in ovarian weight produced in rats by exposure to light for 56 days was prevented by bovine pineal extracts, but these extracts were without effect on the uterine hypertrophy produced under the same conditions. These data suggest that the effect of light upon the weight of the ovary is mediated via the pineal. Many observers have shown that the onset of gonadal maturation and the degree of gonadal activity can be affected in normal animals in at least two ways: a) Environmental factors may be varied: Food, temperature, humidity, light, the presence of eggs or young, and the presence of a companion or mate have all been found to influence gonadal function in different species (Harris