AL amyloidosis, hypothyroidism and reduced tissue availability of thyroid hormones by thyroid hormone‐binding immunoglobulin: a new possible perspective

We read the interesting article by Muchtar et al. [1] on the prevalence of hypothyroidism in AL amyloidosis and its association with survival disadvantage. Particularly, hypothyroid patients had more frequent renal and hepatic involvement by amyloidosis, and a higher light chain burden than euthyroid patients. Uncited in their paper is that primary hypothyroidism is associated with increasing mortality [2], also in renal diseases. We hope to offer the authors a new perspective of viewing and interpreting their data. This article is protected by copyright. All rights reserved.